Measurement of muscle mass in sarcopenia: from imaging to biochemical markers

Sarcopenia encompasses the loss of muscle mass and strength/function during aging. Several methods are available for the estimation of muscle or lean body mass. Popular assessment tools include body imaging techniques (e.g., magnetic resonance imaging, computed tomography, dual X-ray absorptiometry,...

Full description

Saved in:
Bibliographic Details
Published inAging clinical and experimental research Vol. 29; no. 1; pp. 19 - 27
Main Authors Tosato, Matteo, Marzetti, Emanuele, Cesari, Matteo, Savera, Giulia, Miller, Ram R., Bernabei, Roberto, Landi, Francesco, Calvani, Riccardo
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 01.02.2017
Springer Nature B.V
Subjects
Absorptiometry, Photon
Aged
Aged, 80 and over
Aging - physiology
Anthropometry - methods
Biomarkers - blood
Biomarkers - urine
Body Composition
Creatine - analysis
Geriatrics/Gerontology
Humans
Magnetic Resonance Imaging
Medicine
Medicine & Public Health
Muscle Strength
Muscle, Skeletal - chemistry
Muscle, Skeletal - diagnostic imaging
Muscle, Skeletal - pathology
Muscle, Skeletal - physiopathology
Myography - methods
Potassium - analysis
Review Article
Sarcopenia
Sarcopenia - diagnosis
Sarcopenia - physiopathology
Tomography, X-Ray Computed
Body imaging
Muscle strength
Biomarkers
Diagnosis
DXA
Physical function
Appendicular lean mass
Online AccessGet full text

Cover

More Information
Summary:Sarcopenia encompasses the loss of muscle mass and strength/function during aging. Several methods are available for the estimation of muscle or lean body mass. Popular assessment tools include body imaging techniques (e.g., magnetic resonance imaging, computed tomography, dual X-ray absorptiometry, ultrasonography), bioelectric impedance analysis, anthropometric parameters (e.g., calf circumference, mid-arm muscle circumference), and biochemical markers (total or partial body potassium, serum and urinary creatinine, deuterated creatine dilution method). The heterogeneity of the populations to be evaluated as well as the setting in which sarcopenia is investigated impacts the definition of “gold standard” assessment techniques. The aim of this article is to critically review available methods for muscle mass estimation, highlighting strengths and weaknesses of each of them as well as their proposed field of application.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
ISSN:1720-8319
1594-0667
1720-8319
DOI:10.1007/s40520-016-0717-0