Interference of apoptosis in the pathophysiology of subarachnoid hemorrhage

Programmed cell death is crucial for the correct development of the organism and the clearance of harmful cells like tumor cells or autoreactive immune cells. Apoptosis is initiated by the activation of cell death receptors and in most cases it is associated with the activation of the cysteine prote...

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Bibliographic Details
Published inAsian journal of neurosurgery Vol. 8; no. 2; pp. 106 - 111
Main Authors Palade, C, Ciurea, Alexandru, Nica, D, Savu, R, Moisa, Horatiu
Format Journal Article
LanguageEnglish
Published A-12, 2nd Floor, Sector 2, Noida-201301 UP, India Thieme Medical and Scientific Publishers Pvt. Ltd 01.04.2013
Annals of Cardiac Anaesthesia
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt Ltd
Subjects
Apoptosis
Causes of
Physiology, Pathological
Review
REVIEW ARTICLE
Subarachnoid hemorrhage
Sudden death
India
programmed cell death
subarachnoid hemorrhage
cell death receptors
Apoptosis
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Summary:Programmed cell death is crucial for the correct development of the organism and the clearance of harmful cells like tumor cells or autoreactive immune cells. Apoptosis is initiated by the activation of cell death receptors and in most cases it is associated with the activation of the cysteine proteases, which lead to apoptotic cell death. Cells shrink, chromatin clumps and forms a large, sharply demarcated, crescent-shaped or round mass; the nucleus condenses, apoptotic bodies are formed and eventually dead cells are engulfed by a neighboring cell or cleared by phagocytosis. The authors have summarized the most important data concerning apoptosis in subarachnoid hemorrhage that have been issued in the medical literature in the last 20 years.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:1793-5482
2248-9614
DOI:10.4103/1793-5482.116389