Quantitative Radiographic Study of New Bone Formed Around The Implant Using a Parametric X-ray Method

• Published in: Journal of Hard Tissue Biology Vol. 16; no. 3; pp. 139 - 141
• Main Authors: Suwa, Taketoshi, Sakae, Toshiro, Nakada, Hiroshi, Numata, Yasuko, Sato, Isamu
• Format: Journal Article
• Language: English
• Published: THE SOCIETY FOR HARD TISSUE REGENERATIVE BIOLOGY 01.01.2007; The Society for Hard Tissue Regenerative Biology
• Subjects: Implants; LEBRA-PXR; Rabbit tibia
• ISSN: 1341-7649; 1880-828X
• DOI: 10.2485/jhtb.16.139

Bone formed around implant was characterized and grouped into three categories by Nakada et al.1,2) and Suwa et al.3) In order to clarify these bone tissues, we have utilized radiography with a newly developed wavelength tunable and highly parallel Parametric X-ray (PXR) in the Laboratory for Electron Beam Research and Application (LEBRA) of Nihon University. Methods: Ti-alloy implants modified with coating or blasting were used in this study. These materials were implanted in the tibia of rabbits. After 1, 2 and 4 weeks of implantation, non-demineralized polished thin sections were cut. PXR was generated by a LINAC in the LEBRA of Nihon University. X-ray wavelength was tuned from 7 KeV, 0.177 nm to 16 KeV, 0.0775 nm; irradiation: 900 sec; sample-detector distance: 7.5 mm and recording film: Fuji Film Imaging Plate. The obtained images were processed by NIH image analyzer. Results: PXR radiography showed the clear difference between the newly formed bone and the compact bone. Estimated percentage for the newly formed and pre-existing bone were 8.27 % and 20.9 %, respectively. Conclusion: LEBRA-PXR could be a good tool for the quantitative analysis of bone formation.