Evaluation of developmental toxicity data: a discussion of some pertinent factors and a proposal
There is currently no well-accepted standard method for evaluation of developmental toxicity data. This paper presents one approach to the evaluation of developmental toxicity data. We initially identify some pertinent factors that influence the interpretation of animal data and summarize the litera...
Saved in:
| Published in | Risk analysis Vol. 8; no. 1; p. 59 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
01.03.1988
|
| Subjects | |
| Online Access | Get more information |
Cover
Loading…
| Abstract | There is currently no well-accepted standard method for evaluation of developmental toxicity data. This paper presents one approach to the evaluation of developmental toxicity data. We initially identify some pertinent factors that influence the interpretation of animal data and summarize the literature pertaining to these factors. Such factors include the quality and quantity of data and the relationship between maternal and developmental toxicity. We proceed with a discussion of quantitative assessment of data and propose schemes for qualitative and quantitative developmental hazard assessments. |
|---|---|
| AbstractList | There is currently no well-accepted standard method for evaluation of developmental toxicity data. This paper presents one approach to the evaluation of developmental toxicity data. We initially identify some pertinent factors that influence the interpretation of animal data and summarize the literature pertaining to these factors. Such factors include the quality and quantity of data and the relationship between maternal and developmental toxicity. We proceed with a discussion of quantitative assessment of data and propose schemes for qualitative and quantitative developmental hazard assessments. |
| Author | Bell, R H Hart, W L Ely, T S Raleigh, R L Krasavage, W J Reynolds, R C |
| Author_xml | – sequence: 1 givenname: W L surname: Hart fullname: Hart, W L organization: Eastman Kodak Company, Health and Environment Laboratories, Rochester, New York 14650 – sequence: 2 givenname: R C surname: Reynolds fullname: Reynolds, R C – sequence: 3 givenname: W J surname: Krasavage fullname: Krasavage, W J – sequence: 4 givenname: T S surname: Ely fullname: Ely, T S – sequence: 5 givenname: R H surname: Bell fullname: Bell, R H – sequence: 6 givenname: R L surname: Raleigh fullname: Raleigh, R L |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/3287508$$D View this record in MEDLINE/PubMed |
| BookMark | eNotj8tqwzAURLVISZO0n1AQ3dvVw7bk7kpI00Kgm3adXslX4GBbxpJD8vcVNLMZBg7DzJosBj8gIc-c5Tzp5ZTzUtZZVYsi57XWeTSM87LILwuyYkKJrJBS3JN1CCfGOGOlWpKlFFqVTK_I7-4M3Qyx9QP1jjZ4xs6PPQ4ROhr9pbVtvNIGIrxSoE0b7BzCDQ6-RzriFNsh8dSBjX4KFIYmoePkRx-geyB3DrqAjzffkJ_33ff2Izt87T-3b4fMFlKn_agkyoJJUFwbJqSUNhnXAlIwyjlXVgKgBuactUbVyjDECk0iGmnEhjz9946z6bE5jlPbw3Q93p6KP9x2Wcg |
| CitedBy_id | crossref_primary_10_1016_0273_2300_92_90057_G crossref_primary_10_1080_10807039509379983 crossref_primary_10_1016_0273_2300_88_90004_9 crossref_primary_10_3109_10915819109078653 crossref_primary_10_1016_S0890_6238_97_00014_2 crossref_primary_10_1016_0890_6238_93_90069_J crossref_primary_10_1016_0273_2300_89_90050_0 crossref_primary_10_1007_BF00626344 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM |
| DOI | 10.1111/j.1539-6924.1988.tb01154.x |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) |
| DatabaseTitleList | MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Engineering Mathematics |
| ExternalDocumentID | 3287508 |
| Genre | Journal Article Review |
| GroupedDBID | --- .3N .86 .GA .Y3 05W 0R~ 0U7 10A 123 1OB 1OC 29P 31~ 33P 36B 4.4 50Y 50Z 51W 51Y 52M 52O 52Q 52S 52T 52U 52W 53G 5HH 5LA 5VS 66C 6KP 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 8V8 8WZ 930 A04 A6W A8Z AABNI AAESR AAHHS AAIAL AAONW AAOUF AASGY AAXRX AAYZH AAZKR ABCQN ABCUV ABEFU ABEML ABIVO ABJNI ABPVW ABSOO ACAHQ ACBKW ACBWZ ACCFJ ACCZN ACFBH ACGFS ACHQT ACIWK ACPOU ACPRK ACSCC ACXQS ADBBV ADEMA ADEOM ADINQ ADIZJ ADKYN ADMGS ADQRH ADXAS ADZMN AEEZP AEIGN AEIMD AEMOZ AENEX AEQDE AEUQT AEUYR AFBPY AFEBI AFFNX AFFPM AFGKR AFKFF AFPWT AFRAH AFZJQ AHBTC AHBYD AHEFC AHSBF AIFKG AIURR AIWBW AJBDE AKVCP ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN AMBMR AMKLP AMYDB ASPBG ASTYK AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BGNMA BMKGK BMXJE BNVMJ BQESF BROTX BRXPI BY8 CAG CGR COF CS3 CUY CVF D-C D-D DC6 DCZOG DL5 DPXWK DR2 DRFUL DRSSH DU5 DXH EBA EBC EBD EBE EBO EBR EBS EBU ECM EDH EHE EIF EJD EMB EMK EMOBN ESTFP F00 F01 F3I F5P FEDTE FIL G-S G.N G50 GODZA HG6 HGLYW HVGLF HZI HZ~ I09 IHE IX1 J0M K1G KDC LAK LATKE LC2 LC4 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES M4Y MEWTI MK4 MRFUL MRSSH MSFUL MSSSH MXFUL MXSSH N04 N06 N9A NF~ NPM NU0 O66 O9- OIG OVD P2P P2W P2Y P4C PALCI PQQKQ Q.N Q11 QB0 R.K RIWAO RJQFR RNI ROL RPX RSV RX1 RZC RZD SAMSI SDH SEV SUPJJ SV3 TEORI TH9 TN5 TSK U2A U5U UB1 V8K W8V W99 WBKPD WEBCB WH7 WIH WII WOHZO WQZ WRC WSUWO WXSBR XG1 XSW Y6R YHZ YNT ZGI ZXP ZZTAW ~02 ~IA ~KM ~WP |
| ID | FETCH-LOGICAL-c4389-6e73e3403a718b02333cb02182a023b7fff562aa9a0ffccb797b0ee6eb82ad3b2 |
| ISSN | 0272-4332 |
| IngestDate | Tue Oct 15 23:14:09 EDT 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c4389-6e73e3403a718b02333cb02182a023b7fff562aa9a0ffccb797b0ee6eb82ad3b2 |
| PMID | 3287508 |
| ParticipantIDs | pubmed_primary_3287508 |
| PublicationCentury | 1900 |
| PublicationDate | March 1988 |
| PublicationDateYYYYMMDD | 1988-03-01 |
| PublicationDate_xml | – month: 03 year: 1988 text: March 1988 |
| PublicationDecade | 1980 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Risk analysis |
| PublicationTitleAlternate | Risk Anal |
| PublicationYear | 1988 |
| SSID | ssj0010057 |
| Score | 1.3729718 |
| SecondaryResourceType | review_article |
| Snippet | There is currently no well-accepted standard method for evaluation of developmental toxicity data. This paper presents one approach to the evaluation of... |
| SourceID | pubmed |
| SourceType | Index Database |
| StartPage | 59 |
| SubjectTerms | Animals Female Fetus - drug effects Humans Occupational Diseases - chemically induced Pregnancy Prenatal Exposure Delayed Effects Risk Toxicology - methods |
| Title | Evaluation of developmental toxicity data: a discussion of some pertinent factors and a proposal |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/3287508 |
| Volume | 8 |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LS8QwEA4-EPQgPvFNDt6kUk368iayIooeZJf1pkmagKDbxV1F_fXOJGnja0W9lG0b2t3O1-Gb2ZlvCNlmvMwh8EmiwhgIUEyZRwKYRJQmGt69mJnSzow8v0hPOvz0KrkKOV3bXTKUu-r1276S_1gVjoFdsUv2D5ZtLgoH4DPYF7ZgYdj-ysatRqobOV8Z6n-wgrx6vlVIsbEG1LU0YwfuI1a92uWD6l6javEQeCYKNPnBO1a8Fcu2-tXA37_W78YqdOFFTILncj0_3Z0mi3ypX3rVXelSOCELe_YgBuJJuFHu3fB3VMvNum77JGzpWvLyPJRgeUe1n9nOqw9eNf8CHuchnf73aMedMAAKBIW7eCfMW6NekCvpfGfR_r01KYN4L7G6ED-f_CSp7c-Mk_EsR994gRmeeupF7NRh69_khWp99deIbzdNpvw1P0UnlqW058isDy_oocPKPBnTvQUy8050EvbOG6XewSK5CRiilaEfMERrDFHE0AEVNCAIFyOCaIMg6hFEAUGwtEbQEukct9pHJ5GfuhEpDuw1SnXGNOMxE0BbJFA6xpS0Qv8CdmRmjAHOLEQhYmOUklmRyVjrVEtYUTK5v0wmelVPrxC6x3VcxCo1hUx4pqU0CthrqQWXXHCmVsmye1jXfSetcu2f4tqoE-tkOiBwg0waeJP1JtDCodyydnwDK3lfww |
| link.rule.ids | 783 |
| linkProvider | National Library of Medicine |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Evaluation+of+developmental+toxicity+data%3A+a+discussion+of+some+pertinent+factors+and+a+proposal&rft.jtitle=Risk+analysis&rft.au=Hart%2C+W+L&rft.au=Reynolds%2C+R+C&rft.au=Krasavage%2C+W+J&rft.au=Ely%2C+T+S&rft.date=1988-03-01&rft.issn=0272-4332&rft.volume=8&rft.issue=1&rft.spage=59&rft_id=info:doi/10.1111%2Fj.1539-6924.1988.tb01154.x&rft_id=info%3Apmid%2F3287508&rft_id=info%3Apmid%2F3287508&rft.externalDocID=3287508 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0272-4332&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0272-4332&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0272-4332&client=summon |