Relaxin Receptor LGR7 (RXFP1) Is Regulated by Estrogen
Estrogen regulates LGR7 (RXFP1) mRNA expression in an in vitro model of human term pregnancy cervix that utilizes lower uterine segment fibroblasts. LGR7 mRNA levels were increased by estradiol to mean levels of 152%± 5.9% above those in untreated control cells. Therefore, estradiol may amplify rela...
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Published in | Annals of the New York Academy of Sciences Vol. 1160; no. 1; pp. 91 - 92 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Malden, USA
Blackwell Publishing Inc
01.04.2009
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Subjects | |
Online Access | Get full text |
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Summary: | Estrogen regulates LGR7 (RXFP1) mRNA expression in an in vitro model of human term pregnancy cervix that utilizes lower uterine segment fibroblasts. LGR7 mRNA levels were increased by estradiol to mean levels of 152%± 5.9% above those in untreated control cells. Therefore, estradiol may amplify relaxin's actions in the cervix. |
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Bibliography: | istex:46BBF6ACDDB0A06535D2924EB3A001D93098E34E ark:/67375/WNG-F2CK13S1-9 ArticleID:NYAS04048 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
ISSN: | 0077-8923 1749-6632 |
DOI: | 10.1111/j.1749-6632.2009.04048.x |