Connexin43 Expression in the Testis of Frog Rana Esculenta: Sex Hormonal Regulation

Spermatogenesis is the process of proliferating and differentiating germ cells that require highly coordinated cellular interactions. Intercellular junctions are important in maintaining communication between testicular cells. In particular, gap junctions play an important role in this event. Connex...

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Published inAnnals of the New York Academy of Sciences Vol. 1163; no. 1; pp. 425 - 427
Main Authors Izzo, G., Ferrara, D., Delrio, G., D'Istria, M., Minucci, S.
Format Journal Article
LanguageEnglish
Published Malden, USA Blackwell Publishing Inc 01.04.2009
Subjects
Animals
Connexin 43 - genetics
Connexin 43 - metabolism
connexin43
Gene Expression Regulation - genetics
Gonadal Steroid Hormones - metabolism
Male
Rana esculenta
Rana esculenta - metabolism
sexual hormones
testis
Testis - metabolism
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Summary:Spermatogenesis is the process of proliferating and differentiating germ cells that require highly coordinated cellular interactions. Intercellular junctions are important in maintaining communication between testicular cells. In particular, gap junctions play an important role in this event. Connexin43 (Cx43) is the most abundant protein forming a gap junction in a vertebrate testis. It is expressed in several cells types of Rana esculenta testes. The use of reverse transcriptase‐PCR analysis demonstrates that expression levels of Cx43 are regulated by estradiol and testosterone in both in vivo and in vitro experiments.
Bibliography:istex:4469B6EB33DC7DC4EFD39EC7D78C593F59115865
ArticleID:NYAS03651
ark:/67375/WNG-XX4TGXWB-P
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0077-8923
1749-6632
1930-6547
DOI:10.1111/j.1749-6632.2008.03651.x