HLA-B SNA antigen: a BW6 associated B locus antigen belonging to the B5 CREG
A new B locus antigen has been found in members of two unrelated families and in a patient originating from Morocco belonging to the Berber population. A complete analysis has been performed with antisera from the 9th and 10th IHWS defining the B5 CREG antigens. Serology, absorption experiments and...
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Published in | Tissue antigens Vol. 33; no. 3; p. 400 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
England
01.03.1989
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Subjects | |
Online Access | Get more information |
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Summary: | A new B locus antigen has been found in members of two unrelated families and in a patient originating from Morocco belonging to the Berber population. A complete analysis has been performed with antisera from the 9th and 10th IHWS defining the B5 CREG antigens. Serology, absorption experiments and family studies indicate that SNA antigen is a Bw6 associated subtype of B5 antigen closely related to but clearly distinct from each of the B5 CREG antigens. One-dimensional isoelectric focusing study (1D-IEF) confirms that the SNA antigen precipitates as a B locus gene product and has an isoelectric point identical to that of Bw52 and one of the charge variants of B51. |
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ISSN: | 0001-2815 |
DOI: | 10.1111/j.1399-0039.1989.tb01683.x |