Clinical impact of surveillance for head and neck cancer in patients with esophageal squamous cell carcinoma
AIM To evaluate the clinical impact of surveillance for head and neck(HN) region with narrow band imaging(NBI) in patients with esophageal squamous cell carcinoma(ESCC).METHODS Since 2006, we introduced the surveillance for HN region using NBI for all patients with ESCC beforetreatment, and each fol...
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Published in | World journal of gastroenterology : WJG Vol. 23; no. 6; pp. 1051 - 1058 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Baishideng Publishing Group Inc
14.02.2017
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Subjects | |
Online Access | Get full text |
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Summary: | AIM To evaluate the clinical impact of surveillance for head and neck(HN) region with narrow band imaging(NBI) in patients with esophageal squamous cell carcinoma(ESCC).METHODS Since 2006, we introduced the surveillance for HN region using NBI for all patients with ESCC beforetreatment, and each follow-up. The patients with newly diagnosed stage Ⅰ to Ⅲ ESCC were enrolled and classified into two groups as follows: Group A(no surveillance for HN region); between 1992 and 2000), and Group B (surveillance for HN region with NBI; between 2006 and 2008). We comparatively evaluated the detection rate of superficial head and neck squamous cell carcinoma (HNSCC), and the serious events due to metachronous advanced HNSCC during the follow-up.RESULTS A total 561 patients(group A: 254, group B: 307) were enrolled. Synchronous superficial HNSCC was detected in 1 patient (0.3%) in group A, and in 12 (3.9%) in group B (P=0.008). During the follow up period, metachronous HNSCC were detected in 10 patients(3.9%) in group A and in 30 patients(9.8%) in group B(P = 0.008). All metachronous lesions in group B were early stage, and 26 patients underwent local resection, however, 6 of 10 patients (60%) in group A lost their laryngeal function and died with metachronous HNSCC.CONCLUSION Surveillance for the HN region by using NBI endoscopy increase the detection rate of early HNSCC in patients with ESCC, and led to decrease serious events related to advanced metachronous HNSCC. |
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Bibliography: | Hiroyuki Morimoto;Tomonori Yano;Yusuke Yoda;Yasuhiro Oono;Hiroaki Ikematsu;Ryuichi Hayashi;Atsushi Ohtsu;Kazuhiro Kaneko;Department of Gastroenterology and Endoscopy,National Cancer Center Hospital East;Course of Advanced Clinical Research of Cancer,Juntendo University Graduate School of Medicine;Department of Head and Neck Surgery,National Cancer Center Hospital East;National Cancer Center Hospital East;Division of Science and Technology for Endoscopy,National Cancer Center Hospital East ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Telephone: +81-4-71331111 Fax: +81-4-71314724 Author contributions: Morimoto H and Yano T contributed equally to this work; Morimoto H and Yano T designed the research; Morimoto H, Yano T, Yoda Y, Oono Y, Ikematsu H and Kaneko K acquired data and performed the research; Morimoto H, Yano T and Kaneko K wrote the draft; Hayashi R and Ohtsu A supervised the report. Correspondence to: Tomonori Yano, MD, Chief, Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Kashiwanoha 6-5-1, Kashiwa, Chiba 277-8577, Japan. toyano@east.ncc.go.jp |
ISSN: | 1007-9327 2219-2840 |
DOI: | 10.3748/wjg.v23.i6.1051 |