The European mesothelioma epidemic

• Published in: British journal of cancer Vol. 79; no. 3-4; pp. 666 - 672
• Main Authors: PETO, J, DECARLI, A, LA VECCHIA, C, LEVIS, F, NEGRI, E
• Format: Journal Article
• Language: English
• Published: Basingstoke Nature Publishing Group 01.02.1999
• Subjects: Adult; Aged; Asbestos - adverse effects; Biological and medical sciences; Disease Outbreaks - statistics & numerical data; Epidemiology; Europe - epidemiology; Forecasting; Humans; Incidence; Male; Medical sciences; Mesothelioma - mortality; Middle Aged; Mortality - trends; Pleural Neoplasms - mortality; Pneumology; Regular; Risk Assessment; Tumors; Tumors of the respiratory system and mediastinum; Europe; Epidemic; Respiratory disease; Age criterion; Mesothelioma; Malignant tumor; Epidemiology; Modeling; Incidence; Malignant mesothelioma; Risk factor; Pleural disease; Tumor; Pleura
• ISSN: 0007-0920; 1532-1827
• DOI: 10.1038/sj.bjc.6690105

Projections for the period 1995-2029 suggest that the number of men dying from mesothelioma in Western Europe each year will almost double over the next 20 years, from 5000 in 1998 to about 9000 around 2018, and then decline, with a total of about a quarter of a million deaths over the next 35 years. The highest risk will be suffered by men born around 1945-50, of whom about 1 in 150 will die of mesothelioma. Asbestos use in Western Europe remained high until 1980, and substantial quantities are still used in several European countries. These projections are based on the fit of a simple age and birth cohort model to male pleural cancer mortality from 1970 to 1989 for six countries (Britain, France, Germany, Italy, The Netherlands and Switzerland) which together account for three-quarters of the population of Western Europe. The model was tested by comparing observed and predicted numbers of deaths for the period 1990-94. The ratio of mesothelioma to recorded pleural cancer mortality has been 1.6:1 in Britain but was assumed to be 1:1 in other countries.