A new hemostatic clip for endoscopic surgery that can maintain blood flow after clipping

AIM: To develop a new hemostatic device for endoscopic surgery that can control the bleeding without completely occluding the bleeding vessel. METHODS: A hemostatic clip and its applier that can stanch bleeding while maintaining blood flow through the clipped vessel was introduced, and the performan...

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Published inWorld journal of gastroenterology : WJG Vol. 20; no. 5; pp. 1325 - 1331
Main Authors Nam, Kyoung Won, Lee, Sang Bong, Kim, In Young, Kim, Kwang Gi, Park, Sang Jae
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Co., Limited 07.02.2014
Subjects
Animals
bleeding
Blood Flow Velocity
Blood Loss, Surgical - prevention & control
Brief
clip
Equipment Design
Female
Hemostasis
Hemostatic
Iliac Vein - diagnostic imaging
Iliac Vein - surgery
Laparos
Laparoscopy - instrumentation
Male
Materials Testing
Models, Anatomic
Models, Animal
Models, Cardiovascular
Rats
Regional Blood Flow
Splenic Artery - diagnostic imaging
Splenic Artery - surgery
Splenic Vein - diagnostic imaging
Splenic Vein - surgery
Surgical Instruments
Swine
Time Factors
Ultrasonography, Doppler, Color
Vena Cava, Inferior - diagnostic imaging
Vena Cava, Inferior - surgery
Vessel
Endoscopic surgery
Laparoscopic surgery
Hemostatic clip
Hemostasis
Vessel bleeding
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Summary:AIM: To develop a new hemostatic device for endoscopic surgery that can control the bleeding without completely occluding the bleeding vessel. METHODS: A hemostatic clip and its applier that can stanch bleeding while maintaining blood flow through the clipped vessel was introduced, and the performance of the proposed clip was evaluated using in vitro and in vivo experiments. RESULTS: During in vitro experiments, no leakage was found after clipping at cuts made in artificial vessels, and flow was maintained through the clipped artificial vessels. In experiments on rats, all the implanted clips occluded the target vessels successfully, and no bleeding or tissue damage was observed at the operative site after the rats were euthanized on postoperative day 7. In experiments on pigs, bleeding stopped immediately after partial clipping of a damaged vessel, and some amount of blood flow was consistently maintained through the clipped vessel after hemostasis. CONCLUSION: We believe that the proposed hemostatic clip and clip applier can enhance patient safety during laparoscopic surgery.
Bibliography:Kyoung Won Nam;Sang Bong Lee;In Young Kim;Kwang Gi Kim;Sang Jae Park;Department of Biomedical Engineering, Hanyang University;Biomedical Engineering Branch, National Cancer Center;Center for Liver Cancer, National Cancer Center
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SourceType-Scholarly Journals-1
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Correspondence to: Sang Jae Park, PhD, Center for Liver Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si, Goyang 410-769, South Korea. spark@ncc.re.kr
Telephone: +82-31-9201640 Fax: +82-31-9202006
Author contributions: Kim KG and Park SJ equally contributed to this paper; Nam KW and Lee SB designed the device and performed the research; Kim IY, Park SJ and Kim KG designed the research and contributed to the writing of the paper.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v20.i5.1325