Staphylococcus aureus bacteremia in pediatric patients with cancer

The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S.aureus (MSSA) in children with cancer has not been well studied. A total of 10 MRSA and 42 MSSA isolates from bacteremic episodes were collected from cancer patients from 2000 through 2007. Seventeen...

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Bibliographic Details
Published inThe Pediatric infectious disease journal Vol. 29; no. 2; p. 172
Main Authors Srinivasan, Ashok, Seifried, Steven, Zhu, Liang, Srivastava, Deo K, Flynn, Patricia M, Bankowski, Matthew J, Shenep, Jerry L, Hayden, Randall T
Format Journal Article
LanguageEnglish
Published United States 01.02.2010
Subjects
Adolescent
Bacteremia - epidemiology
Bacteremia - microbiology
Bacterial Typing Techniques
Catheter-Related Infections - epidemiology
Catheter-Related Infections - microbiology
Child
Child, Preschool
Cluster Analysis
DNA Fingerprinting
DNA, Bacterial - genetics
Female
Genotype
Humans
Infant
Male
Methicillin Resistance
Neoplasms - complications
Staphylococcal Infections - epidemiology
Staphylococcal Infections - microbiology
Staphylococcus aureus - isolation & purification
Young Adult
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Summary:The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S.aureus (MSSA) in children with cancer has not been well studied. A total of 10 MRSA and 42 MSSA isolates from bacteremic episodes were collected from cancer patients from 2000 through 2007. Seventeen patients (33%) suffered from complications. Thirty-eight (73%) of the bacteremic episodes were catheter-related. Methicillin resistance was associated with increased catheter removal (P = 0.003), but no increase in complications or adverse outcomes was seen.
ISSN:1532-0987
DOI:10.1097/INF.0b013e3181b9a363