Cardiovascular risk assessment in kidney transplantation

Cardiovascular disease (CVD) remains the most common cause of death after kidney transplantation worldwide, with the highest event rate in the early postoperative period. In an attempt to address this issue, screening for CVD prior to transplant is common, but the clinical utility of screening asymp...

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Bibliographic Details
Published inKidney international Vol. 87; no. 3; pp. 527 - 534
Main Authors Hart, Allyson, Weir, Matthew R., Kasiske, Bertram L.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.03.2015
Elsevier Limited
Subjects
Asymptomatic Diseases
cardiovascular
Coronary Angiography
Coronary Artery Disease - complications
Coronary Artery Disease - diagnosis
Coronary Artery Disease - surgery
Cost-Benefit Analysis
Exercise Test
Humans
Kidney Transplantation - adverse effects
Myocardial Infarction - etiology
Myocardial Infarction - prevention & control
Percutaneous Coronary Intervention
Predictive Value of Tests
Renal Insufficiency, Chronic - surgery
Risk Assessment
Risk Factors
transplantation
Waiting Lists
cardiovascular
risk assessment
transplantation
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Summary:Cardiovascular disease (CVD) remains the most common cause of death after kidney transplantation worldwide, with the highest event rate in the early postoperative period. In an attempt to address this issue, screening for CVD prior to transplant is common, but the clinical utility of screening asymptomatic transplant candidates remains unclear. A large degree of variation exists among both transplant center practice patterns and clinical practice guidelines regarding who should be screened, and opinions are based on mixed observational data with great potential for bias. In this review, we discuss the potential risks, benefits, and evidence for screening for CVD in kidney transplant candidates, and also the next steps to better evaluate and treat asymptomatic kidney transplant candidates.
ISSN:0085-2538
1523-1755
DOI:10.1038/ki.2014.335