Radical gastrectomy with hepatoarterial catheter implantation for late-stage gastric cancer

• Published in: World journal of gastroenterology : WJG Vol. 21; no. 9; pp. 2754 - 2758
• Main Authors: Yao, Guo-Liang, Fan, Yong-Gang, Zhai, Jing-Ming, Lu, Bao-Sai, Liu, Kai-Long
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Inc 07.03.2015
• Subjects: Adult; Aged; Aged, 80 and over; Antineoplastic Agents - administration & dosage; Antineoplastic Agents - adverse effects; cancer;Hepatic; Catheterization - adverse effects; Catheterization - instrumentation; Catheterization - mortality; Catheters, Indwelling; Chemotherapy, Adjuvant; China; Female; Gastrectomy - adverse effects; Gastrectomy - methods; Gastrectomy - mortality; Gastric; Hepatectomy - adverse effects; Hepatectomy - mortality; Hepatic Artery; Humans; Infusions, Intra-Arterial; Kaplan-Meier Estimate; Liver Neoplasms - drug therapy; Liver Neoplasms - mortality; Liver Neoplasms - pathology; Liver Neoplasms - surgery; Male; metastases;Cumulative; Middle Aged; Neoplasm Staging; Palliative Care; Retrospective Studies; Retrospective Study; Stomach Neoplasms - mortality; Stomach Neoplasms - pathology; Stomach Neoplasms - surgery; survi; Time Factors; Treatment Outcome; Young Adult; China; Palliative gastrectomy; Hepatic metastases; Radical gastrectomy; Gastric cancer; Cumulative survival curve
• ISSN: 1007-9327; 2219-2840
• DOI: 10.3748/wjg.v21.i9.2754

AIM:To determine the optimal type of surgery for latestage gastric cancer with hepatic metastases.METHODS:We retrospectively analyzed 49 gastrectomies for late-stage gastric cancer conducted in the FirstHospital Affiliated to Henan University of Science and Technology between September 2003 and September 2010.All gastrectomy operations were divided into two groups:radical resection(gastrectomy and simultaneous resection of hepatic metastases,n =31),and palliative resection(gastrectomy without hepatic resection,n =18).All 49 patients had chemotherapy catheter implantation in the hepatic artery via the gastroduodenal artery.Postoperative complications and cumulative survival rates of the two groups were compared and analyzed.RESULTS:There was no significant difference in the number of perioperative complications between the radical and palliative resection groups(6 and 3 cases,respectively,P > 0.05).The incidence of long-term complications including ileus(3 in the radical resection and 2 in the palliative resection groups) and anastomosis(2 cases in each group) was not significantly different(P > 0.05).The cumulative survival rate was significantly lower in the palliative resection group(P < 0.05).CONCLUSION:Radical gastrectomy with resection of hepatic metastases and hepatoarterial catheter implantation is the recommended surgery for late-stage gastric cancer patients with hepatic metastases.