Virilizing Adrenocortical Oncocytoma in a Child: A Case Report

• Published in: Journal of Korean medical science Vol. 25; no. 7; pp. 1077 - 1079
• Main Authors: Lim, Yeon-Jung, Lee, Se-Min, Shin, Jae-Hun, Koh, Hyun-Chul, Lee, Young-Ho
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Academy of Medical Sciences 01.07.2010; 대한의학회
• Subjects: Adenoma, Oxyphilic - complications; Adenoma, Oxyphilic - metabolism; Adenoma, Oxyphilic - pathology; Adenoma, Oxyphilic - surgery; Adolescent; Adrenal Cortex Neoplasms - complications; Adrenal Cortex Neoplasms - metabolism; Adrenal Cortex Neoplasms - pathology; Adrenal Cortex Neoplasms - surgery; Adrenalectomy; Adult; Case Report; Female; Humans; Male; Middle Aged; Virilism - etiology; Virilism - pathology; Virilism - surgery; 의학일반; Adrenal Cortex Neoplasms; Adenoma, Oxyphilic; Child; Virilism
• ISSN: 1011-8934; 1598-6357; 1598-6357
• DOI: 10.3346/jkms.2010.25.7.1077

Functioning adrenocortical oncocytomas are extremely rare and most reported patients are 40-60 yr of age. To our knowledge, only 2 cases of functioning adrenocortical oncocytomas have been reported in childhood. We report a case of functioning adrenocortical oncocytoma in a 14-yr-old female child presenting with virilization. She presented with deepening of the voice and excessive hair growth, and elevation of plasma testosterone and dehydroepiandrosterone sulfate. She had an adrenalectomy. The completely resected tumor composed predominantly of oncocytes without atypical mitosis and necrosis. A discussion of this case and a review of the literature on this entity are presented.