SnapShot: Extracellular Vesicles

Cells release a variety of extracellular vesicles (EVs; including exosomes, microvesicles, and many others) into their environment. EVs can bud in endosomes or directly at the plasma membrane, carrying a selection of components from the cell and displaying various functional properties. Different te...

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Published inCell Vol. 182; no. 1; pp. 262 - 262.e1
Main Authors Cocozza, Federico, Grisard, Eleonora, Martin-Jaular, Lorena, Mathieu, Mathilde, Théry, Clotilde
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 09.07.2020
Elsevier
Subjects
Endosomes - metabolism
Extracellular Vesicles - metabolism
Humans
Life Sciences
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Summary:Cells release a variety of extracellular vesicles (EVs; including exosomes, microvesicles, and many others) into their environment. EVs can bud in endosomes or directly at the plasma membrane, carrying a selection of components from the cell and displaying various functional properties. Different techniques can be used to separate EV subtypes and EVs from co-isolated components, resulting in preparations of different abundance and purity. Cells release a variety of extracellular vesicles (EVs; including exosomes, microvesicles, and many others) into their environment. EVs can bud in endosomes or directly at the plasma membrane, carrying a selection of components from the cell and displaying various functional properties. Different techniques can be used to separate EV subtypes and EVs from co-isolated components, resulting in preparations of different abundance and purity.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2020.04.054