Perioperative outcomes and complications of intracorporeal vs extracorporeal urinary diversion after robot-assisted radical cystectomy for bladder cancer: a real-life, multi-institutional french study

• Published in: World journal of urology Vol. 36; no. 11; pp. 1711 - 1718
• Main Authors: Lenfant, Louis, Verhoest, Gregory, Campi, Riccardo, Parra, Jérôme, Graffeille, Vivien, Masson-Lecomte, Alexandra, Vordos, Dimitri, de La Taille, Alexandre, Roumiguie, Mathieu, Lesourd, Marine, Taksin, Lionel, Misraï, Vincent, Grande, Pietro, Vaessen, Christophe, Ploussard, Guillaume, Granger, Benjamin, Rouprêt, Morgan
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2018; Springer Nature B.V
• Subjects: Bladder cancer; Cancer; Lymph nodes; Medicine; Medicine & Public Health; Nephrology; Oncology; Robotic surgery; Surgical outcomes; Topic Paper; Urology; Comparative effectiveness research; Cystectomy; Urinary bladder neoplasms; Robotic surgical procedures; Postoperative complications
• ISSN: 0724-4983; 1433-8726
• DOI: 10.1007/s00345-018-2313-8

Purpose To compare perioperative outcomes and complications of extracorporeal (ECUD) vs intracorporeal urinary diversion (ICUD) in patients after undergoing robot-assisted radical cystectomy (RARC) at five referral centers in France. Methods We retrospectively reviewed our multi-institutional, prospectively-collected database to select patients undergoing RARC between 2010 and 2016 with at least 3 months of follow-up. At each center, the surgery was performed by one surgeon with extensive experience in robotic surgery and radical cystectomy but no prior experience in RARC. Results Overall, 108 patients were included. ECUD and ICUD were performed in 34 (31.5%) and 74 (68.5%) patients, respectively. Patient characteristics were comparable among the two groups, except for a higher proportion of patients with high surgical risk (ASA score ≥ 3) in the ECUD group. Ileal conduit and ileal neobladder were performed in 63/108 (58%) and 45/108 (42%) cases, respectively. Ileal conduit was performed more often with an extracorporeal approach while ileal neobladder with an intracorporeal approach. Overall, operative time, length of hospital stay, positive margin rate, and number of lymph nodes removed did not significantly differ among the two cohorts. Estimated blood loss and transfusion rates were significantly higher in the ECUD group. Rate of early (38.2 vs 47.3%, p  = 0.4) and late (29.4 vs 18.9%, p  = 0.2) surgical complications did not significantly differ between the ECUD and ICUD groups. Results were comparable in the subgroup analysis in the ileal conduit subpopulation. Conclusion In our real-life, multi-institutional study, RARC with ICUD achieved perioperative outcomes and complication rates comparable to those of RARC with ECUD.