Burkholderia cepacia in Cystic Fibrosis

To the Editor: Steinbach et al. (Oct. 13 issue) 1 address an important and contentious issue — the transmissibility of Burkholderia (formerly Pseudomonas ) cepacia among patients with cystic fibrosis. The authors used genomic fingerprinting of B. cepacia isolates based on pulsed-field gel electropho...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 332; no. 12; pp. 819 - 821
Main Authors Mahenthiralingam, E, Campbell, M, Speert, D P
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 23.03.1995
Subjects
Burkholderia cepacia - isolation & purification
Cystic Fibrosis - microbiology
Humans
Lung Diseases - microbiology
Pseudomonas Infections - microbiology
Pseudomonas Infections - transmission
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Summary:To the Editor: Steinbach et al. (Oct. 13 issue) 1 address an important and contentious issue — the transmissibility of Burkholderia (formerly Pseudomonas ) cepacia among patients with cystic fibrosis. The authors used genomic fingerprinting of B. cepacia isolates based on pulsed-field gel electrophoresis (PFGE) and concluded that the bacterium was not spread among patients cared for at the University of North Carolina Cystic Fibrosis Center. Their conclusion was based on the observation that genetic differences could be discerned among strains by PFGE (which analyzes the entire bacterial genome) but not by the widely accepted method of ribotype analysis (which detects . . .
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ObjectType-Commentary-2
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM199503233321213