Laparoscopic treatment of complete obliteration of the cul-de-sac associated with endometriosis: long-term follow-up of en bloc resection

• Published in: Fertility and sterility Vol. 76; no. 2; pp. 358 - 365
• Main Authors: Redwine, David B., Wright, Jeremy T.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.08.2001; Elsevier Science
• Subjects: Adult; Biological and medical sciences; Cohort Studies; cul-de-sac obliteration; Douglas' Pouch - pathology; Douglas' Pouch - surgery; endometriosis; Endometriosis - surgery; Female; Follow-Up Studies; Humans; intestine; Laparoscopy; Medical sciences; Outcome Assessment (Health Care); Postoperative Complications; Prognosis; Quality of Life; rectovaginal endometriosis; rectum; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the genital tract and mammary gland; surgical treatment; Surveys and Questionnaires; symptom relief; transvaginal; rectovaginal endometriosis; intestine; endometriosis; surgical treatment; Laparoscopy; cul-de-sac obliteration; rectum; symptom relief; transvaginal; Human; Digestive system; Gut; Laparoscopic surgery; Endometriosis; Female genital diseases; Treatment; Transvaginal route; Surgery; Rectum; Uterine diseases; Female; Obliteration
• ISSN: 0015-0282; 1556-5653
• DOI: 10.1016/S0015-0282(01)01913-6

Objective: To evaluate symptom relief following a laparoscopic technique designed for treatment of complete obliteration of the cul-de-sac associated with endometriosis, with fertility preserved. Design: Preoperative and postoperative questionnaire study of a cohort of patients with complete obliteration of the cul-de-sac undergoing a standardized laparoscopic surgical treatment. Setting: American tertiary referral center for the surgical treatment of endometriosis. Patients: Eighty-four consecutive patients undergoing laparoscopic treatment of endometriosis with complete cul-de-sac obliteration with 67 replying to a postoperative questionnaire. Interventions: Laparoscopic excision of all endometriosis including treatment of complete obliteration of the cul-de-sac by en bloc resection and bowel resection as needed. Main Outcome Measures: Symptom relief as measured on a 5-point ranked ordinal scale administered before and after surgery, as well as perioperative complications, postoperative fertility, and prognostic value of preoperative findings on pelvic examination. Results: Symptom reduction was obtained for all symptoms related to cul-de-sac disease, particularly for patients with severe or debilitating symptoms preoperatively. There was no significant complication, and the postoperative fertility rate was 43%. Seventy-three percent of patients with obliteration of the cul-de-sac had histologically proved rectal endometriosis. Nodularity and tenderness on examination were predictive of symptom improvement. Conclusions: Aggressive laparoscopic excision of endometriosis carried out in a specialist center offers good symptom relief, especially for those with severe or debilitating symptoms. To ensure complete removal of all disease, intestinal surgery is required in most patients with complete obliteration of the cul-de-sac.