Carbapenemase-producing Enterobacteriaceae in South Korea: a report from the National Laboratory Surveillance System
To assess the epidemiology of carbapenemase-producing Enterobacteriaceae (CPE) in South Korea. From 2011 to 2015, 2487 carbapenem-nonsusceptible Enterobacteriaceae were collected through the Korean National Laboratory Surveillance System. Disk-diffusion for antimicrobial susceptibility, PCR/sequenci...
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Published in | Future microbiology Vol. 13; no. 7; pp. 771 - 783 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
England
Future Medicine Ltd
01.06.2018
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Subjects | |
Online Access | Get full text |
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Summary: | To assess the epidemiology of carbapenemase-producing Enterobacteriaceae (CPE) in South Korea.
From 2011 to 2015, 2487 carbapenem-nonsusceptible Enterobacteriaceae were collected through the Korean National Laboratory Surveillance System. Disk-diffusion for antimicrobial susceptibility, PCR/sequencing to detect carbapenemase genes and multilocus sequence typing for molecular epidemiology were carried out.
The number of carbapenem-nonsusceptible Enterobacteriaceae was increasing approximately 1.5-fold per year and the proportion of CPEs was exponentially confirmed from 2014. KPC was the most dominant, mostly associated with
ST11 and ST307, NDM was the second and OXA-48-like was the third dominant carbapenemases. The IMP, VIM and GES-5 CPEs were identified sporadically.
The nation-wide spreads of KPC, NDM and OXA-48-like CPEs were in an alarming epidemiological stage. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1746-0913 1746-0921 |
DOI: | 10.2217/fmb-2018-0022 |