Advancements of chiral molecularly imprinted polymers in separation and sensor fields: A review of the last decade

• Published in: Talanta (Oxford) Vol. 224; p. 121794
• Main Author: Moein, Mohammad Mahdi
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.03.2021
• Subjects: analytical methods; Chiral separation; electrochemistry; Enantiomer; fields; Molecularly imprinted polymer; nanomaterials; polymers; Sensor; separation; Molecularly imprinted polymer; Enantiomer; Chiral separation; Sensor
• ISSN: 0039-9140; 1873-3573; 1873-3573
• DOI: 10.1016/j.talanta.2020.121794

Since chiral recognition mechanism based on molecularly imprinted polymers immerged, it has assisted countless chemical and electrochemical analytical sample preparation techniques. It has done this by enhancing the enatioseparation abilities of these techniques. The preparation and optimization of chiral molecularly imprinted polymers (CMIPs) are two favored methods in the separation and sensor fields. This review aims to present an overview of advances in the preparation and application of CMIPs in analytical approaches in different available formats (eg. column, monolithic column, cartridge, membrane, nanomaterials, pipette tip and stir bar sorptive) over the last decade. In addition, progress in the preparation and development of CMIPs-based sensor fields have been also discussed. Finally, the main application challenges of CMIPs are also summarily explained, as well as upcoming prospects in the field. [Display omitted] •Chiral molecularly imprinted polymers (CMPs) can offer enormous potential in enatioseparation field.•The last decade advances for the preparation of CMIPs in different formats are detailed.•The recent progress on CMIPs in sensor field are reviewed.•Factors affecting the CMIPs performance are commented.•The main challenges and upcoming prospects in CMIPs field are discussed.