The High-Intensity Exercise Study to Attenuate Limitations and Train Habits in Older Adults With HIV (HEALTH): A Research Protocol

The High-Intensity Exercise Study to Attenuate Limitations and Train Habits in Older Adults With HIV (HEALTH), which incorporates an exercise and biobehavioral coaching intervention, has the following overall goals: (a) to determine whether high-intensity interval training (HIIT) mitigates physical...

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Bibliographic Details
Published inThe Journal of the Association of Nurses in AIDS Care Vol. 33; no. 2; pp. 178 - 188
Main Authors Oliveira, Vitor H F, Erlandson, Kristine M, Cook, Paul F, Jankowski, Catherine, MaWhinney, Samantha, Dirajlal-Fargo, Sahera, Knaub, Leslie, Hsiao, Chao-Pin, Horvat Davey, Christine, Webel, Allison R
Format Journal Article
LanguageEnglish
Published United States Lippincott Williams & Wilkins Ovid Technologies 01.03.2022
Subjects
Aged
Aging
Coaching
Exercise
Fatigue
Frailty
Habits
Health promotion
Health status
High-Intensity Interval Training
HIV
HIV Infections
Human immunodeficiency virus
Humans
Intervention
Older people
Physical ability
Physical activity
Physical fitness
Randomized Controlled Trials as Topic
Sedentary
Sedentary Behavior
Self report
Telemedicine
Text messaging
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Summary:The High-Intensity Exercise Study to Attenuate Limitations and Train Habits in Older Adults With HIV (HEALTH), which incorporates an exercise and biobehavioral coaching intervention, has the following overall goals: (a) to determine whether high-intensity interval training (HIIT) mitigates physical function impairments, fatigue, and impairments in mitochondrial bioenergetics of older people living with HIV (PLWH) to a greater extent than continuous moderate exercise (CME); and (b) to determine whether a biobehavioral coaching and mobile health text messaging intervention after HIIT or CME can promote long-term adherence to physical activity. The HEALTH study is a randomized trial of 100 older PLWH (≥50 years of age) who self-report fatigue and have a sedentary lifestyle. Enrolled participants will be randomized to 16 weeks of supervised HIIT or CME training, followed by a 12-week maintenance phase, involving a mobile health coaching intervention. Outcomes of the HEALTH study will inform the development of scalable, effective exercise recommendations tailored to the unique needs of aging PLWH.
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V. H. F. Oliveira contributed to the development of the study’s methodology, wrote the original draft, and revised the manuscript. K. M. Erlandson was responsible for conceptualizing the study, including development of the methodology, secured resources by obtaining grant funding, provided leadership, wrote the original draft, and revised the manuscript. P. F. Cook contributed to the development of the study’s methodology and to the original draft, and revised the manuscript. C. Jankowski contributed to the development of the study’s methodology and to the original draft, and revised the manuscript. S. MaWhinney contributed to the development of the study’s methodology and to the original draft. S. Dirajlal-Fargo contributed to the development of the study’s methodology and to the original draft. L. Knaub contributed to the development of the study’s methodology and to the original draft. C.-P. Hsiao contributed to the development of the study’s methodology and to the original draft. C. Horvat Davey contributed to the development of the study’s methodology and to the original draft. A. R. Webel was responsible for conceptualizing the study, including development of the methodology, secured resources by obtaining grant funding, provided leadership, wrote the original draft, and revised the manuscript.
Author Contributions
ISSN:1055-3290
1552-6917
DOI:10.1097/JNC.0000000000000276