Basic liver immunology
The liver is the largest solid organ in the body and has many unique immunological properties, including induction of immune tolerance, strong innate immunity, poor adaptive immune response versus overreactive autoimmunity and hematopoiesis in the fetal liver. Thus, the liver has been proposed as ＇a...
Saved in:
| Published in | Cellular & molecular immunology Vol. 13; no. 3; pp. 265 - 266 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
London
Nature Publishing Group UK
01.05.2016
Nature Publishing Group |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The liver is the largest solid organ in the body and has many unique immunological properties, including induction of immune tolerance, strong innate immunity, poor adaptive immune response versus overreactive autoimmunity and hematopoiesis in the fetal liver. Thus, the liver has been proposed as ＇an immunological organ＇. Although the primary functions of the liver are not traditionally considered to be immunological, the liver also performs many essential immune tasks. For example, hepatocytes are responsible for the production of 80-90% of the circulating innate immunity proteins in the body, |
|---|---|
| AbstractList | The liver is the largest solid organ in the body and has many unique immunological properties, including induction of immune tolerance, strong innate immunity, poor adaptive immune response versus overreactive autoimmunity and hematopoiesis in the fetal liver. Thus, the liver has been proposed as ＇an immunological organ＇. Although the primary functions of the liver are not traditionally considered to be immunological, the liver also performs many essential immune tasks. For example, hepatocytes are responsible for the production of 80-90% of the circulating innate immunity proteins in the body, |
| Author | Bin Gao |
| AuthorAffiliation | Laboratory of Liver Diseases, National Institute onAlcohol Abuse and Alcoholism （NIAAA）, NationalInstitutes of Health （NIH）, Bethesda, MD 20892,USA |
| Author_xml | – sequence: 1 givenname: Bin surname: Gao fullname: Gao, Bin email: bgao@mail.nih.gov organization: Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institutes of Health (NIH) |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27041634$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkc1LxDAQxYMoun6cBI8iehG06yRNk_QiqPgFghc9hzTNrpE20aQV_O9N2XVRURACgeT33ryZWUfLzjuD0DaGMYZcnOjWjglgNoZyCY0IUJIBIWwZjTDjJONM4DW0HuMzQCEop6tojXCgmOV0hHbOVbR6r7FvJuzZtu2db_z0fROtTFQTzdb83kCPV5cPFzfZ3f317cXZXaZpzrrM1KBwpQSmE2Mw0EJATYt8Uoiy5ppCOhXWqWyVXrgBJnStSRJRzRTUVb6BTme-L33Vmlob1wXVyJdgWxXepVdWfv9x9klO_Zukokh9kWRwODcI_rU3sZOtjdo0jXLG91FiXkKZ54yLf6CCgygEKxN68AN99n1waRIDxQohcFkkavdr-EXqz-km4GgG6OBjDGayQDDIYXcy7U4Ou5MwFMU_aG071Vk_dG6bPzTHM01Mzm5qwpegv-L78xJP3k1fk2KRiDHBKaUM5x8J-LRY |
| CitedBy_id | crossref_primary_10_3389_fimmu_2022_865888 crossref_primary_10_3389_fimmu_2021_729143 crossref_primary_10_1016_j_jff_2019_103569 crossref_primary_10_1007_s00432_024_05856_6 crossref_primary_10_3390_ijms22136777 crossref_primary_10_2174_0118715303250788231018080821 crossref_primary_10_3390_biomedicines8120628 crossref_primary_10_1186_s12917_022_03388_0 crossref_primary_10_3389_fimmu_2017_01095 crossref_primary_10_3390_cells11193001 crossref_primary_10_1016_j_intimp_2020_106604 crossref_primary_10_3389_fvets_2023_1126911 crossref_primary_10_3390_pharmaceutics10040278 crossref_primary_10_1111_sji_13208 crossref_primary_10_3389_fendo_2023_1232171 crossref_primary_10_3390_pathogens10091074 crossref_primary_10_1016_j_jcmgh_2023_08_012 crossref_primary_10_1007_s12016_020_08778_6 crossref_primary_10_2147_JHC_S221187 crossref_primary_10_1016_j_immuni_2018_12_024 crossref_primary_10_1016_j_jtemb_2022_127030 crossref_primary_10_1016_j_tice_2023_102198 crossref_primary_10_3389_fgene_2019_00117 crossref_primary_10_1038_s41598_018_32975_1 crossref_primary_10_3389_fimmu_2019_02525 crossref_primary_10_3748_wjg_v28_i23_2527 crossref_primary_10_1155_2019_3954890 crossref_primary_10_1152_ajpcell_00214_2022 crossref_primary_10_1007_s11684_018_0622_3 crossref_primary_10_1515_biol_2022_0950 crossref_primary_10_1039_D2NH00289B crossref_primary_10_1002_smtd_202201421 crossref_primary_10_1177_10600280211047864 crossref_primary_10_3389_fimmu_2023_1206025 crossref_primary_10_1038_s41593_021_00969_4 crossref_primary_10_3389_fimmu_2017_00695 crossref_primary_10_1172_JCI137553 crossref_primary_10_1038_s41423_019_0199_z crossref_primary_10_1016_j_jtherbio_2019_07_003 crossref_primary_10_1111_imm_13193 crossref_primary_10_1186_s12865_017_0199_7 crossref_primary_10_1002_jbt_22220 crossref_primary_10_1155_2019_1475163 crossref_primary_10_3389_fimmu_2019_01582 crossref_primary_10_1007_s11427_018_9407_2 crossref_primary_10_1016_j_ygeno_2022_110283 crossref_primary_10_1186_s12915_022_01459_0 crossref_primary_10_3390_md19090525 crossref_primary_10_1093_hmg_ddy300 crossref_primary_10_1155_2022_9018811 crossref_primary_10_3389_fmicb_2021_740464 crossref_primary_10_1097_TP_0000000000005274 crossref_primary_10_1016_j_biopha_2023_115216 crossref_primary_10_1155_2022_1372705 crossref_primary_10_1002_bmm2_12129 crossref_primary_10_52419_issn2072_2419_2023_3_94 crossref_primary_10_1177_1091581819898399 crossref_primary_10_1002_hep4_1061 crossref_primary_10_4254_wjh_v13_i3_343 crossref_primary_10_1016_j_jaut_2017_02_005 crossref_primary_10_1172_JCI135048 crossref_primary_10_3389_fimmu_2023_1205821 crossref_primary_10_1016_j_jtherbio_2020_102573 crossref_primary_10_3389_fimmu_2023_1166171 crossref_primary_10_1016_j_hermed_2020_100411 crossref_primary_10_17352_atte_000011 crossref_primary_10_1111_sji_13363 crossref_primary_10_3389_fcell_2020_615131 crossref_primary_10_1038_nrgastro_2016_154 crossref_primary_10_3390_mi11090849 crossref_primary_10_3389_fphar_2017_00591 crossref_primary_10_1016_j_intimp_2024_112091 crossref_primary_10_1016_j_jfma_2024_06_003 crossref_primary_10_1002_eji_202149641 crossref_primary_10_1152_ajpgi_00331_2018 crossref_primary_10_1038_s41423_020_00607_2 crossref_primary_10_3390_ijms19092634 crossref_primary_10_1007_s11684_018_0621_4 crossref_primary_10_3389_fendo_2023_1286979 crossref_primary_10_1016_j_smim_2017_07_009 crossref_primary_10_1016_j_heliyon_2023_e22918 crossref_primary_10_1371_journal_ppat_1006694 crossref_primary_10_1016_j_jhepr_2024_101323 crossref_primary_10_1097_MEG_0000000000002034 crossref_primary_10_3390_microorganisms12091887 crossref_primary_10_1016_j_cld_2018_12_007 |
| Cites_doi | 10.1038/nm0296-198 10.1038/cmi.2015.97 10.1038/cmi.2015.104 10.1038/cmi.2015.96 10.1002/hep.21060 10.1002/hep.22034 10.1007/BF00224305 10.1038/cmi.2015.109 10.1097/00075198-200104000-00008 10.1038/cmi.2016.4 10.1038/cmi.2016.5 10.1038/cmi.2015.112 10.1002/cphy.c120011 10.1172/JCI66381 10.1038/cmi.2015.115 10.1146/annurev.immunol.021908.132629 10.1038/cmi.2016.3 |
| ContentType | Journal Article |
| Copyright | Chinese Society of Immunology and The University of Science and Technology of China 2016 Copyright Nature Publishing Group May 2016 Copyright © 2016 Chinese Society of Immunology and The University of Science and Technology of China 2016 Chinese Society of Immunology and The University of Science and Technology of China |
| Copyright_xml | – notice: Chinese Society of Immunology and The University of Science and Technology of China 2016 – notice: Copyright Nature Publishing Group May 2016 – notice: Copyright © 2016 Chinese Society of Immunology and The University of Science and Technology of China 2016 Chinese Society of Immunology and The University of Science and Technology of China |
| DBID | 2RA 92L CQIGP W91 ~WA AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7X7 7XB 88E 8FE 8FH 8FI 8FJ 8FK ABUWG AFKRA AZQEC BBNVY BENPR BHPHI CCPQU DWQXO FYUFA GHDGH GNUQQ HCIFZ K9. LK8 M0S M1P M7P PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS 7X8 7T5 H94 5PM |
| DOI | 10.1038/cmi.2016.09 |
| DatabaseName | 维普期刊资源整合服务平台 中文科技期刊数据库-CALIS站点 维普中文期刊数据库 中文科技期刊数据库-医药卫生 中文科技期刊数据库- 镜像站点 CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Collection ProQuest Central Natural Science Collection ProQuest One ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Biological Sciences ProQuest Health & Medical Collection Medical Database Biological Science Database ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic Immunology Abstracts AIDS and Cancer Research Abstracts PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Central China ProQuest Central ProQuest One Applied & Life Sciences ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Biological Science Collection ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic AIDS and Cancer Research Abstracts Immunology Abstracts |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology |
| DocumentTitleAlternate | Basic liver immunology Editorial |
| EISSN | 2042-0226 |
| EndPage | 266 |
| ExternalDocumentID | PMC4856812 4043938411 27041634 10_1038_cmi_2016_09 668744461 |
| Genre | Introductory Journal Article Editorial |
| GroupedDBID | --- -05 -0E -Q- -SE -S~ 0R~ 29B 2B. 2C~ 2RA 2WC 3V. 4.4 406 53G 5GY 5VR 6J9 70F 7X7 88E 8FE 8FH 8FI 8FJ 92F 92I 92L 92M 93N 93R 9D9 9DE AADWK AANZL AATNV AAWBL AAYFA AAYJO AAZLF ABAWZ ABGIJ ABJNI ABKZE ABUWG ACAOD ACBMV ACBRV ACBYP ACGFS ACIGE ACKTT ACPRK ACRQY ACTTH ACVWB ACZOJ ADFRT ADHDB ADMDM ADQMX ADYYL AEDAW AEFTE AEJRE AENEX AEVLU AEXYK AFKRA AFNRJ AFSHS AFUIB AGAYW AGEZK AGGBP AGHAI AHMBA AHSBF AILAN AJCLW AJDOV AJRNO ALMA_UNASSIGNED_HOLDINGS AMRJV AMYLF AXYYD BBNVY BENPR BHPHI BKKNO BPHCQ BVXVI CAJEE CAJUS CCEZO CCPQU CHBEP CIEJG CQIGP CW9 DIK DNIVK DPUIP DU5 EBLON EBS EE. EIOEI EJD F5P FA0 FDQFY FERAY FIZPM FRP FSGXE FYUFA GX1 HCIFZ HMCUK HYE HZ~ IWAJR JUIAU JZLTJ KQ8 LK8 M1P M7P NAO NQJWS NYICJ O9- OK1 P6G PQQKQ PROAC PSQYO Q-- Q-4 R-E RNT RNTTT RPM RT5 S.. SNX SNYQT SRMVM SWTZT T8U TAOOD TBHMF TCJ TDRGL TGQ TR2 TSG U1F U1G U5E U5O UKHRP W91 WFFXF ~88 ~MX ~WA AACDK AASML AAXDM ABAKF ABZZP AEFQL AEMSY AFBBN AGQEE AIGIU ALIPV FIGPU ROL AAYXX ABBRH ABDBE ABFSG ACMFV ACSTC AEZWR AFDZB AFHIU AHWEU AIXLP ATHPR AYFIA CITATION PHGZM PHGZT SOJ CGR CUY CVF ECM EIF NPM 7XB 8FK ABRTQ AZQEC DWQXO GNUQQ K9. PJZUB PKEHL PPXIY PQEST PQGLB PQUKI PRINS 7X8 7T5 H94 5PM |
| ID | FETCH-LOGICAL-c436t-ed0a1ba814fee104580d453f589d7c40c40b1c058b5897e068cdc2d0a4c6a0db3 |
| IEDL.DBID | 7X7 |
| ISSN | 1672-7681 2042-0226 |
| IngestDate | Thu Aug 21 18:23:00 EDT 2025 Thu Jul 10 23:01:51 EDT 2025 Fri Jul 11 08:38:36 EDT 2025 Fri Jul 25 09:03:51 EDT 2025 Thu Apr 03 07:05:28 EDT 2025 Tue Jul 01 01:08:42 EDT 2025 Thu Apr 24 22:53:54 EDT 2025 Fri Feb 21 02:37:09 EST 2025 Wed Feb 14 10:18:29 EST 2024 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c436t-ed0a1ba814fee104580d453f589d7c40c40b1c058b5897e068cdc2d0a4c6a0db3 |
| Notes | 11-4987/R The liver is the largest solid organ in the body and has many unique immunological properties, including induction of immune tolerance, strong innate immunity, poor adaptive immune response versus overreactive autoimmunity and hematopoiesis in the fetal liver. Thus, the liver has been proposed as ＇an immunological organ＇. Although the primary functions of the liver are not traditionally considered to be immunological, the liver also performs many essential immune tasks. For example, hepatocytes are responsible for the production of 80-90% of the circulating innate immunity proteins in the body ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 ObjectType-Editorial-2 ObjectType-Commentary-1 ObjectType-Article-3 |
| OpenAccessLink | https://www.nature.com/articles/cmi20169.pdf |
| PMID | 27041634 |
| PQID | 1786588195 |
| PQPubID | 2041960 |
| PageCount | 2 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_4856812 proquest_miscellaneous_1790933678 proquest_miscellaneous_1787085869 proquest_journals_1786588195 pubmed_primary_27041634 crossref_primary_10_1038_cmi_2016_09 crossref_citationtrail_10_1038_cmi_2016_09 springer_journals_10_1038_cmi_2016_09 chongqing_primary_668744461 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2016-05-01 |
| PublicationDateYYYYMMDD | 2016-05-01 |
| PublicationDate_xml | – month: 05 year: 2016 text: 2016-05-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | London |
| PublicationPlace_xml | – name: London – name: China |
| PublicationTitle | Cellular & molecular immunology |
| PublicationTitleAbbrev | Cell Mol Immunol |
| PublicationTitleAlternate | Cellular ＆ Molecular Immunology |
| PublicationYear | 2016 |
| Publisher | Nature Publishing Group UK Nature Publishing Group |
| Publisher_xml | – name: Nature Publishing Group UK – name: Nature Publishing Group |
| References | Taniguchi, Toyoshima, Fukao, Nakauchi (CR17) 1996; 2 Bogdanos, Gao, Gershwin (CR4) 2013; 3 Peng, Wisse, Tian (CR11) 2015; 13 CR6 Grakoui, Crispe (CR8) 2016; 13 Crispe (CR5) 2009; 27 CR7 Ju, Tacke (CR10) 2016; 13 Peng, Jiang, Chen, Sojka, Wei, Gao (CR16) 2013; 123 Zhou, Xu, Gao (CR9) 2015; 13 CR14 Wisse, van't Noordende, van der Meulen, Daems (CR15) 1976; 173 CR13 Gao, Jeong, Tian (CR2) 2008; 47 CR12 Sheth, Bankey (CR3) 2001; 7 Racanelli, Rehermann (CR1) 2006; 43 Hui Peng (BFcmi20169_CR11) 2015; 13 V Racanelli (BFcmi20169_CR1) 2006; 43 Cynthia Ju (BFcmi20169_CR10) 2016; 13 Arash Grakoui (BFcmi20169_CR8) 2016; 13 B Gao (BFcmi20169_CR2) 2008; 47 K Sheth (BFcmi20169_CR3) 2001; 7 E Wisse (BFcmi20169_CR15) 1976; 173 DP Bogdanos (BFcmi20169_CR4) 2013; 3 H Peng (BFcmi20169_CR16) 2013; 123 H Taniguchi (BFcmi20169_CR17) 1996; 2 BFcmi20169_CR6 BFcmi20169_CR7 IN Crispe (BFcmi20169_CR5) 2009; 27 BFcmi20169_CR12 Zhou Zhou (BFcmi20169_CR9) 2015; 13 BFcmi20169_CR13 BFcmi20169_CR14 8574965 - Nat Med. 1996 Feb;2(2):198-203 19302037 - Annu Rev Immunol. 2009;27:147-63 23524967 - J Clin Invest. 2013 Apr;123(4):1444-56 27041636 - Cell Mol Immunol. 2016 May;13(3):347-53 26972772 - Cell Mol Immunol. 2016 May;13(3):337-46 991252 - Cell Tissue Res. 1976 Oct 19;173(4):423-35 18167066 - Hepatology. 2008 Feb;47(2):729-36 23720323 - Compr Physiol. 2013 Apr;3(2):567-98 26685902 - Cell Mol Immunol. 2016 May;13(3):301-15 27041638 - Cell Mol Immunol. 2016 May;13(3):277-92 27063467 - Cell Mol Immunol. 2016 May;13(3):267-76 26908374 - Cell Mol Immunol. 2016 May;13(3):316-27 16447271 - Hepatology. 2006 Feb;43(2 Suppl 1):S54-62 11373518 - Curr Opin Crit Care. 2001 Apr;7(2):99-104 |
| References_xml | – volume: 2 start-page: 198 year: 1996 end-page: 203 ident: CR17 article-title: Presence of hematopoietic stem cells in the adult liver publication-title: Nat Med doi: 10.1038/nm0296-198 – volume: 13 start-page: 301 issue: 3 year: 2015 end-page: 315 ident: CR9 article-title: Hepatocytes: a key cell type for innate immunity publication-title: Cellular & Molecular Immunology doi: 10.1038/cmi.2015.97 – volume: 13 start-page: 316 issue: 3 year: 2016 end-page: 327 ident: CR10 article-title: Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies publication-title: Cellular & Molecular Immunology doi: 10.1038/cmi.2015.104 – ident: CR14 – volume: 27 start-page: 147 year: 2009 end-page: 163 ident: CR5 article-title: The liver as a lymphoid organ publication-title: Annu Rev Immunol – ident: CR12 – volume: 13 start-page: 328 issue: 3 year: 2015 end-page: 336 ident: CR11 article-title: Liver natural killer cells: subsets and roles in liver immunity publication-title: Cellular & Molecular Immunology doi: 10.1038/cmi.2015.96 – volume: 43 start-page: S54 year: 2006 end-page: S62 ident: CR1 article-title: The liver as an immunological organ publication-title: Hepatology doi: 10.1002/hep.21060 – ident: CR13 – volume: 47 start-page: 729 year: 2008 end-page: 736 ident: CR2 article-title: Liver: an organ with predominant innate immunity publication-title: Hepatology doi: 10.1002/hep.22034 – volume: 3 start-page: 567 year: 2013 end-page: 598 ident: CR4 article-title: Liver immunology publication-title: Compr Physiol – ident: CR6 – volume: 173 start-page: 423 year: 1976 end-page: 435 ident: CR15 article-title: The pit cell: description of a new type of cell occurring in rat liver sinusoids and peripheral blood publication-title: Cell Tissue Res doi: 10.1007/BF00224305 – volume: 123 start-page: 1444 year: 2013 end-page: 1456 ident: CR16 article-title: Liver-resident NK cells confer adaptive immunity in skin-contact inflammation publication-title: J Clin Invest – ident: CR7 – volume: 13 start-page: 293 issue: 3 year: 2016 end-page: 300 ident: CR8 article-title: Presentation of hepatocellular antigens publication-title: Cellular & Molecular Immunology doi: 10.1038/cmi.2015.109 – volume: 7 start-page: 99 year: 2001 end-page: 104 ident: CR3 article-title: The liver as an immune organ publication-title: Curr Opin Crit Care doi: 10.1097/00075198-200104000-00008 – volume: 13 start-page: 316 issue: 3 year: 2016 ident: BFcmi20169_CR10 publication-title: Cellular & Molecular Immunology doi: 10.1038/cmi.2015.104 – ident: BFcmi20169_CR14 doi: 10.1038/cmi.2016.4 – volume: 13 start-page: 328 issue: 3 year: 2015 ident: BFcmi20169_CR11 publication-title: Cellular & Molecular Immunology doi: 10.1038/cmi.2015.96 – ident: BFcmi20169_CR13 doi: 10.1038/cmi.2016.5 – ident: BFcmi20169_CR7 doi: 10.1038/cmi.2015.112 – volume: 47 start-page: 729 year: 2008 ident: BFcmi20169_CR2 publication-title: Hepatology doi: 10.1002/hep.22034 – volume: 2 start-page: 198 year: 1996 ident: BFcmi20169_CR17 publication-title: Nat Med doi: 10.1038/nm0296-198 – volume: 3 start-page: 567 year: 2013 ident: BFcmi20169_CR4 publication-title: Compr Physiol doi: 10.1002/cphy.c120011 – volume: 123 start-page: 1444 year: 2013 ident: BFcmi20169_CR16 publication-title: J Clin Invest doi: 10.1172/JCI66381 – ident: BFcmi20169_CR12 doi: 10.1038/cmi.2015.115 – volume: 13 start-page: 301 issue: 3 year: 2015 ident: BFcmi20169_CR9 publication-title: Cellular & Molecular Immunology doi: 10.1038/cmi.2015.97 – volume: 173 start-page: 423 year: 1976 ident: BFcmi20169_CR15 publication-title: Cell Tissue Res doi: 10.1007/BF00224305 – volume: 43 start-page: S54 year: 2006 ident: BFcmi20169_CR1 publication-title: Hepatology doi: 10.1002/hep.21060 – volume: 7 start-page: 99 year: 2001 ident: BFcmi20169_CR3 publication-title: Curr Opin Crit Care doi: 10.1097/00075198-200104000-00008 – volume: 27 start-page: 147 year: 2009 ident: BFcmi20169_CR5 publication-title: Annu Rev Immunol doi: 10.1146/annurev.immunol.021908.132629 – ident: BFcmi20169_CR6 doi: 10.1038/cmi.2016.3 – volume: 13 start-page: 293 issue: 3 year: 2016 ident: BFcmi20169_CR8 publication-title: Cellular & Molecular Immunology doi: 10.1038/cmi.2015.109 – reference: 19302037 - Annu Rev Immunol. 2009;27:147-63 – reference: 8574965 - Nat Med. 1996 Feb;2(2):198-203 – reference: 18167066 - Hepatology. 2008 Feb;47(2):729-36 – reference: 16447271 - Hepatology. 2006 Feb;43(2 Suppl 1):S54-62 – reference: 23524967 - J Clin Invest. 2013 Apr;123(4):1444-56 – reference: 27041638 - Cell Mol Immunol. 2016 May;13(3):277-92 – reference: 11373518 - Curr Opin Crit Care. 2001 Apr;7(2):99-104 – reference: 27063467 - Cell Mol Immunol. 2016 May;13(3):267-76 – reference: 26685902 - Cell Mol Immunol. 2016 May;13(3):301-15 – reference: 26972772 - Cell Mol Immunol. 2016 May;13(3):337-46 – reference: 991252 - Cell Tissue Res. 1976 Oct 19;173(4):423-35 – reference: 27041636 - Cell Mol Immunol. 2016 May;13(3):347-53 – reference: 23720323 - Compr Physiol. 2013 Apr;3(2):567-98 – reference: 26908374 - Cell Mol Immunol. 2016 May;13(3):316-27 |
| SSID | ssj0058474 |
| Score | 2.4128764 |
| Snippet | The liver is the largest solid organ in the body and has many unique immunological properties, including induction of immune tolerance, strong innate immunity,... |
| SourceID | pubmedcentral proquest pubmed crossref springer chongqing |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 265 |
| SubjectTerms | Allergy and Immunology Antibodies Biomedical and Life Sciences Biomedicine editorial Immunology Liver - immunology Medical Microbiology Microbiology Vaccine 先天免疫 免疫器官 免疫学基础 免疫学特性 免疫耐受 肝脏 自身免疫 造血功能 |
| Title | Basic liver immunology |
| URI | http://lib.cqvip.com/qk/87787X/201603/668744461.html https://link.springer.com/article/10.1038/cmi.2016.09 https://www.ncbi.nlm.nih.gov/pubmed/27041634 https://www.proquest.com/docview/1786588195 https://www.proquest.com/docview/1787085869 https://www.proquest.com/docview/1790933678 https://pubmed.ncbi.nlm.nih.gov/PMC4856812 |
| Volume | 13 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS-QwEB88Rc4XOb3zrn6xgvci9GzabJI-ySmKCIqIwr6F5qPegtdVd_fh_vubST90XREKhWZaMjNp5pfMZAZgv_Qex4pxsVUyjXlqythkMo8ZRSympTIqFO27vBLnd_xi0B80G27jJqyynRPDRO1GlvbID5lUaCzJ63P0-BRT1SjyrjYlND7BEqUuo1EtB92CizyAwasssBsIq1lzPi_J1KH9O6S4LvGLIhE_40xT3T-hrZi1TnOQcz5y8o37NFilsy-w2sDJ3u9a_2uw4Kt1WK4LTP77ChvHBWqh90DBF70hHQUJDd_g7uz09uQ8biohxJZnYhJ7lxTMFIpxlC0j32bieD8r-yp30vIEL8MsMmzwifSJUNbZFF_iVhSJM9kGLFajyv-AHi74vC-ls6ro89QiIuCWpS5HmIQ3wyPY6qShH-uMF1oIypLPBYvgoJWPtk0Scapl8aCDMztTGgWrSbA6ySPY74jbL71Ltt0KWjc_0Fi_qDuCva4Zhz75M4rKj6aBRiJiVCL_iCanPRs0yRF8r3XX9SWVCcFRZFnOaLUjoNTbsy3V8E9Iwc1VSNwWwc9W_6-6Ps_i5scsbsEKEdZxlNuwOHme-h3EOhOzGwb0Liwdn15d3_wHzQT9Lw |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VIlQuqDxaQgsEqb0ghTqJYzsHVPGqtvRxaqW9mfgRWKlkW7oV6p_iNzLjPGBZ1FulSJHiSWTPjD2fM-MZgK3ae9QV4xKrZJbwzNSJyWWZpBSxmNXKqFC07-hYjE7553ExXoJf_VkYCqvs18SwULuppX_kO6lUaCzJ67N7fpFQ1SjyrvYlNFq1OPDXP3HLdvl2_yPKdzvL9j6dfBglXVWBxPJczBLvWJWaSqUc-5mSn5A5XuR1oUonLWd4mdSyQhl8Ij0Tyjqb4Uvcioo5k-N378BdNLyMNntyPGzwyOMYvNgCh40wPu3OA7Jc7djvE4ojE28o8nEFV7bm6wXapnlruABxFyM1_3HXBiu4twoPOvgav2v17SEs-eYR3GsLWl4_hrX3FUo9PqNgj3hCR09CwxM4vRUercFyM238U4hxg-l9LZ1VVcEziwiE2zRzJcIyvBkewcbADX3eZtjQQlBWfi7SCF73_NG2S1pOtTPOdHCe50ojYzUxVrMygq2BuP_Sf8k2e0brbsJe6j_qFcGroRmnGvlPqsZPrwKNRISqRHkTTUn_iBACRLDeym7oSyYZwV8cspyT6kBAqb7nW5rJt5Dym6uQKC6C7V7-f3V9cYjPbh7iS1gZnRwd6sP944MNuE8vtTGcm7A8-3HlnyPOmpkXQblj-HLbs-k3eQY40w |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Zb9QwEB6VrTheEFdpaIEgtS9IYXM4tvOAEKVdtRRWFaJS39z4CF2pZFu6Fepf49cx4xywLOpbpUiR4nFkj8eez57xDMBG5RzKiraRkSKNWKqrSGeiiBLyWEwrqaVP2vd5zHcP2cej_GgJfnV3YcitslsT_UJtp4bOyIeJkKgsyeozrFq3iIPt0buz84gySJGltUun0YjIvrv6idu3i7d72zjWm2k62vn6YTdqMwxEhmV8Fjkbl4kuZcKwzQnZDGPL8qzKZWGFYTE-OjFxLjV-ES7m0liTYiVmeBlbneF_b8GyoF3RAJa3dsYHXzo9QPZHb9PmyAQE9Ul7OzDO5NB8n5BXGX9DfpB3cZ2rv52jpprXjQuAd9Fv8x_jrdeJowdwvwWz4ftG-h7Ckqsfwe0mveXVY1jZKlEGwlNy_QgndBHFFzyBwxvh0goM6mntViHE7aZzlbBGljlLDeIRZpLUFgjS8KVZAGs9N9RZE29DcU4x-hlPAnjd8UeZNoQ5ZdI4Vd6UnkmFjFXEWBUXAWz0xN2f_ku23jFatdP3Qv0RtgBe9cU48ciaUtZueulpBOJVyYvraAo6MUJAEMDTZuz6tqQiJjCMXRZzo9oTUODv-ZJ6cuIDgDPpw8YFsNmN_19NX-zis-u7-BLu4ExSn_bG-2twj-o0Dp3rMJj9uHTPEXTN9ItWukM4vukJ9RtsZj5u |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Basic+liver+immunology&rft.jtitle=Cellular+%26+molecular+immunology&rft.au=Gao%2C+Bin&rft.date=2016-05-01&rft.pub=Nature+Publishing+Group&rft.issn=1672-7681&rft.eissn=2042-0226&rft.volume=13&rft.issue=3&rft.spage=265&rft_id=info:doi/10.1038%2Fcmi.2016.09&rft.externalDBID=HAS_PDF_LINK&rft.externalDocID=4043938411 |
| thumbnail_s | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fimage.cqvip.com%2Fvip1000%2Fqk%2F87787X%2F87787X.jpg |