Basic liver immunology

The liver is the largest solid organ in the body and has many unique immunological properties, including induction of immune tolerance, strong innate immunity, poor adaptive immune response versus overreactive autoimmunity and hematopoiesis in the fetal liver. Thus, the liver has been proposed as ＇a...

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Bibliographic Details
Published inCellular & molecular immunology Vol. 13; no. 3; pp. 265 - 266
Main Author Gao, Bin
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.05.2016
Nature Publishing Group
Subjects
Allergy and Immunology
Antibodies
Biomedical and Life Sciences
Biomedicine
editorial
Immunology
Liver - immunology
Medical Microbiology
Microbiology
Vaccine
先天免疫
免疫器官
免疫学基础
免疫学特性
免疫耐受
肝脏
自身免疫
造血功能
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Summary:The liver is the largest solid organ in the body and has many unique immunological properties, including induction of immune tolerance, strong innate immunity, poor adaptive immune response versus overreactive autoimmunity and hematopoiesis in the fetal liver. Thus, the liver has been proposed as ＇an immunological organ＇. Although the primary functions of the liver are not traditionally considered to be immunological, the liver also performs many essential immune tasks. For example, hepatocytes are responsible for the production of 80-90% of the circulating innate immunity proteins in the body,
Bibliography:11-4987/R
The liver is the largest solid organ in the body and has many unique immunological properties, including induction of immune tolerance, strong innate immunity, poor adaptive immune response versus overreactive autoimmunity and hematopoiesis in the fetal liver. Thus, the liver has been proposed as ＇an immunological organ＇. Although the primary functions of the liver are not traditionally considered to be immunological, the liver also performs many essential immune tasks. For example, hepatocytes are responsible for the production of 80-90% of the circulating innate immunity proteins in the body
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ISSN:1672-7681
2042-0226
2042-0226
DOI:10.1038/cmi.2016.09