Facilitation of serotonin-induced contraction of rat mesenteric artery by ketamine

• Published in: The Korean journal of physiology & pharmacology Vol. 20; no. 6; pp. 605 - 611
• Main Authors: Park, Sang Woong, Noh, Hyun Ju, Kim, Jung Min, Kim, Bokyung, Cho, Sung-Il, Kim, Yoon Soo, Woo, Nam Sik, Kim, Sung Hun, Bae, Young Min
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Physiological Society and The Korean Society of Pharmacology 01.11.2016; 대한약리학회
• Subjects: Original; 약리학; Schizophrenia; 5-HT2A receptor; Mesenteric artery; Blood pressure; Ketamine

Ketamine is an anesthetic with hypertensive effects, which make it useful for patients at risk of shock. However, previous studies reported vasodilatory actions of ketamine in isolated arteries. In this study, we reexamined the effects of ketamine on arterial tones in the presence and absence of phy...