Fulminant Epstein-Barr virus (EBV) hepatitis in a young immunocompetent subject

• Published in: Médecine et maladies infectieuses Vol. 36; no. 7; pp. 396 - 398
• Main Authors: Ader, F., Chatellier, D., Le Berre, R., Morand, P., Fourrier, F.
• Format: Journal Article
• Language: English
• Published: Paris Elsevier SAS 01.07.2006; Elsevier
• Subjects: Adolescent; Biological and medical sciences; DNA, Viral - genetics; DNA, Viral - isolation & purification; Epstein-Barr virus; Epstein-Barr Virus Infections - diagnosis; Fatal Outcome; Fulminant hepatitis; Hepatitis - virology; Herpesvirus 4, Human - genetics; Herpesvirus 4, Human - isolation & purification; Human viral diseases; Humans; Hépatite fulminante; Immunocompetence; Infectious diseases; Infectious mononucleosis; Male; Medical sciences; Mononucléose infectieuse; Polymerase Chain Reaction; Viral diseases; Viral diseases of the respiratory system and ent viral diseases; Viral hepatitis; Virus Epstein-Barr; Fulminant hepatitis; Virus Epstein-Barr; Epstein-Barr virus; Hépatite fulminante; Infectious mononucleosis; Mononucléose infectieuse; Gammaherpesvirinae; Human; Hepatitis A virus; Picornaviridae; Herpesviridae; Hepatic disease; Epstein Barr virus; Fulminant; Hepatovirus; Infection; Virus; Viral hepatitis A; Viral disease; Digestive diseases
• ISSN: 0399-077X; 1769-6690
• DOI: 10.1016/j.medmal.2006.03.002

We report a case of fulminant hepatitis related to a primary Epstein-Barr virus (EBV) infection in an immunocompetent 15-year-old male patient. The main causes of fulminant hepatitis are viral infections, drugs, and autoimmune diseases. Primary Epstein-Barr virus infection is usually a benign, self-limited disease in pediatrics but can exceptionally be fatal. Nous rapportons le cas d'une hépatite fulminante à virus Epstein-Barr (EBV) chez un jeune patient immunocompétent de 15 ans. Les causes principales d'hépatite fulminante sont les infections virales, les médicaments et les maladies auto-immunes. La primo-infection à EBV est généralement bénigne et spontanément régressive chez les enfants et adolescents mais peut exceptionnellement être fatale.