18F-FDG PET/CT Evaluation of Thymomas: a Pictorial Review

The World Health Organization classification divides thymomas according to morphology, epithelial component, and cell atypia. They are grouped into 3 large subgroups: low-risk thymomas (types A, AB, and B1), high-risk thymomas (types B2 and B3), and thymic carcinomas. Tumor subtype represents an ind...

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Published inNuclear medicine and molecular imaging Vol. 55; no. 4; pp. 186 - 193
Main Authors Murad, Vanessa, Kim, E. Edmund
Format Journal Article
LanguageEnglish
Published Singapore Springer Singapore 01.08.2021
Springer Nature B.V
대한핵의학회
Subjects
Cardiology
Fluorine isotopes
Imaging
Interesting Image
Medicine
Medicine & Public Health
Morphology
Nuclear Medicine
Oncology
Orthopedics
Radiology
Subgroups
Tomography
방사선과학
Thymomas
Nuclear medicine
Oncology
Thymic epithelial tumors
F-FDG PET-CT
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Summary:The World Health Organization classification divides thymomas according to morphology, epithelial component, and cell atypia. They are grouped into 3 large subgroups: low-risk thymomas (types A, AB, and B1), high-risk thymomas (types B2 and B3), and thymic carcinomas. Tumor subtype represents an independent prognostic factor, which determines therapeutic decision. All thymomas show some degree of 18 F-FDG uptake, which tends to increase with the grade of malignancy; this is related to glucose transporter 1 (GLUT1) expression. This review collects all types of thymomas with illustrative images and provides a guide to get familiar with histological characteristics of the lesions and have them in mind because, even imaging findings can overlap among subtypes, certain characteristics can be combined to make an accurate diagnosis based on 18 F-FDG PET-CT findings.
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ISSN:1869-3474
1869-3482
DOI:10.1007/s13139-021-00705-7