A new triterpenoid saponin with inhibition of luteal cell from the seeds of Vaccaria segetalis

• Published in: Journal of asian natural products research Vol. 4; no. 4; pp. 297 - 301
• Main Authors: Sang, Sheng-Min, Lao, Ai-Na, Leng, Ying, Cao, Lin, Chen, Zhong-Liang, Uzawa, Jun, Shigeo, Yoshida, Fujimoto, Yasuo
• Format: Journal Article
• Language: English
• Published: ABINGDON Taylor & Francis Group 01.12.2002; Taylor & Francis
• Subjects: Animals; Biological and medical sciences; Caryophyllaceae; Chemistry; Chemistry, Applied; Chemistry, Medicinal; Female; General pharmacology; Life Sciences & Biomedicine; Luteal Cell; Luteal Cells - drug effects; Luteal Cells - physiology; Medical sciences; Pharmacognosy. Homeopathy. Health food; Pharmacology & Pharmacy; Pharmacology. Drug treatments; Physical Sciences; Plant Sciences; Rats; Saponins - chemistry; Saponins - isolation & purification; Saponins - pharmacology; Science & Technology; Segetoside B; Triterpenes - chemistry; Triterpenes - pharmacology; Triterpenoid Saponins; Vaccaria - chemistry; Vaccaria Segetalis; Asia; China; triterpenoid saponins; segetoside B; Vaccaria segetalis; luteal cell; Caryophyllaceae; Pentacyclic compound; Seeds; Rat; Toxicity; Cytotoxicity; Disaccharide; Medicinal plant; Saponin; Ester; Folk medicine; Luteal cell; Dicotyledones; Angiospermae; Glycoside; Terpenoid; Pharmacognosy; Oriental medicine; Rodentia; Aldehyde; Biological activity; Oleanane derivatives; Vertebrata; Mammalia; Animal; Plant origin; Triterpene; Uronic acid; Isolation; Spermatophyta; Tetrasaccharide; Structural analysis
• ISSN: 1028-6020; 1477-2213
• DOI: 10.1080/1028602021000049096

A new triterpenoid saponin, named segetoside B, showing inhibition of luteal cell activity, has been isolated from the seeds of Vaccaria segetalis. On the basis of chemical reactions and spectral analyses, its structure has been established as 28-O-[ g -D-xylopyranosyl-(1 M 4)- f -L-rhamnopyranosyl-(1 M 2)]-[ f -L-(5-O-acetyl)arabinofuranosyl-(1 M 3)]- g -D-(4-O-acetyl)fucopyranosyl-gypsogenin-3-O- g -D-galactopyranosyl-(1 M 2)- g -D-(6- O -methyl ester)-glucuronopyranoside.