MicroRNAs in Sarcopenia: A Systematic Review

Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation of target messenger RNAs. Previous studies ha...

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Published inFrontiers in medicine Vol. 7; p. 180
Main Authors Yanai, Katsunori, Kaneko, Shohei, Ishii, Hiroki, Aomatsu, Akinori, Ito, Kiyonori, Hirai, Keiji, Ookawara, Susumu, Ishibashi, Kenichi, Morishita, Yoshiyuki
Format Journal Article
LanguageEnglish
Published Frontiers Media S.A 28.05.2020
Subjects
Medicine
microRNA
myoblast
myocyte
myotube
sarcopenia
systematic review
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Summary:Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation of target messenger RNAs. Previous studies have shown that miRNAs play pivotal roles in the development of sarcopenia. Therefore, this systematic review focuses on miRNAs that regulate sarcopenia.
Bibliography:content type line 23
SourceType-Scholarly Journals-1
This article was submitted to Nephrology, a section of the journal Frontiers in Medicine
Edited by: Christos Argyropoulos, University of New Mexico, United States
Reviewed by: Christiaan Leeuwenburgh, University of Florida, United States; Anna Picca, Catholic University of the Sacred Heart, Italy
ISSN:2296-858X
2296-858X
DOI:10.3389/fmed.2020.00180