A homologue of a gene implicated in the virulence of human fungal diseases is present in a plant fungal pathogen and is expressed during infection

• Published in: Physiological and molecular plant pathology Vol. 55; no. 1; pp. 69 - 73
• Main Authors: HALL, N, KEON, J.P.R, HARGREAVES, J.A
• Format: Journal Article
• Language: English
• Published: London Elsevier India Pvt Ltd 01.07.1999; Elsevier
• Subjects: amino acid sequences; Aspergillus fumigatus; Biological and medical sciences; Coccidioides immitis; complementary DNA; extracellular peptide; Fundamental and applied biological sciences. Psychology; Fungal plant pathogens; genbank/af074941; gene expression; gene sequence; genes; infection; Leptosphaeria nodorum; Magnaporthe grisea; molecular sequence data; nucleotide sequences; pathogencity; pathogenicity; Phytopathology. Animal pests. Plant and forest protection; protein transport; proteins; secretion; Stagonospora nodorum; Triticum aestivum; Variation, races, biotypes, parasitic specialization, genetics; virulence; wheat disease; extracellular peptide; wheat disease; virulence; gene sequence; pathogencity; Coccidioides immitis; Plant pathogen; Nucleotide sequence; Virulence; Phycomycetes; Homology; Gene expression; Fungi; Infection; Pathogenicity; Gene; Pathogenic; Stagonospora nodorum; Ascomycetes; Fungi Imperfecti; Aspergillus fumigatus; Thallophyta
• ISSN: 0885-5765; 1096-1178
• DOI: 10.1006/pmpp.1999.0203

The gene encoding SnodProt1 (SP1), an extracellular protein secreted by the wheat fungal pathogen,Stagonospora (Septoria) nodorum , has been isolated and characterised. The deduced amino acid sequence exhibits significant similarity to antigenic and allergenic proteins encoded by genes cloned from the human fungal pathogens,Coccidioides immitis and Aspergillus fumigatus , respectively. SP1 also exhibits similarity to an EST cDNA derived from the rice blast fungus, Magnaporthe grisea , grown on isolated rice cell walls. Northern and Western blot analyses show that the gene encoding SP1 is expressed and that the protein is secreted during infection of wheat leaves.