Insects Go on a STING Operation to Tackle Intracellular Invaders

Insect immunity to extracellular microbes relies largely on the TOLL and IMD pathways. In this issue of Immunity, Goto et al. (2018) report that the IKKβ-Relish module of the IMD pathway hitches up the intracellular sensor STING to activate antiviral responses in Drosophila. Insect immunity to extra...

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Published inImmunity (Cambridge, Mass.) Vol. 49; no. 2; pp. 195 - 197
Main Authors Zakovic, Suzana, Levashina, Elena A.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 21.08.2018
Elsevier Limited
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Summary:Insect immunity to extracellular microbes relies largely on the TOLL and IMD pathways. In this issue of Immunity, Goto et al. (2018) report that the IKKβ-Relish module of the IMD pathway hitches up the intracellular sensor STING to activate antiviral responses in Drosophila. Insect immunity to extracellular microbes relies largely on the TOLL and IMD pathways. In this issue of Immunity, Goto et al. (2018) report that the IIKKβ-Relish module of the IMD pathway hitches up the intracellular sensor STING to activate antiviral responses in Drosophila.
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ISSN:1074-7613
1097-4180
DOI:10.1016/j.immuni.2018.08.003