The Small-Aperture IC-8 Intraocular Lens: A New Concept for Added Depth of Focus in Cataract Patients

• Published in: American journal of ophthalmology Vol. 160; no. 6; pp. 1176 - 1184.e1
• Main Authors: Grabner, Günther, Ang, Robert Edward, Vilupuru, Srividhya
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2015; Elsevier Limited
• Subjects: Adult; Aperture; Cataract - physiopathology; Cataracts; Confidence intervals; Female; Follow-Up Studies; Funding; Humans; Lenses, Intraocular; Male; Middle Aged; Ophthalmology; Optics; Prospective Studies; Prosthesis Design; Pseudophakia - surgery; Refraction, Ocular; Standard deviation; Transplants & implants; Vision, Binocular; Visual Acuity
• ISSN: 0002-9394; 1879-1891
• DOI: 10.1016/j.ajo.2015.08.017

Purpose To evaluate visual performance of subjects implanted monocularly with a small-aperture hydrophobic intraocular lens (IC-8 IOL). Design A prospective, noncomparative, multicenter case series. Methods A series of 12 patients, presenting for cataract surgery, were implanted monocularly with a single-piece hydrophobic acrylic intraocular with a centrally located opaque annular mask measuring 3.23 mm in total diameter with a 1.36 mm central aperture. Uncorrected distance, intermediate, and near visual acuities (UDVA, UIVA, and UNVA); depth of focus; and subjective symptoms were evaluated for 12 months after implantation. Mean ± standard deviation visual acuity is reported in logMAR. Results The mean monocular UDVA, UIVA, and UNVA improved significantly from 0.42 ± 0.18, 0.52 ± 0.22 and 0.66 ± 0.23 preoperatively to 0.06 ± 0.08 ( P < .0001), 0.07 ± 0.11 ( P < .0001), and 0.11 ± 0.15 ( P < .0001) at 1 month, respectively, and remained stable until 12 months. At 12 months, 100%, 100%, and 92% of patients achieved 20/32 or better binocularly for UDVA, UIVA, and UNVA, respectively. One hundred percent of eyes maintained 20/40 or better visual acuity over a range of +0.50 diopter to −1.50 diopters of defocus. Subjects implanted with the IC-8 IOL perceived a small magnitude of visual symptoms and rated their symptoms on the lower end of the severity scale. Conclusion Early results demonstrate that monocular IC-8 intraocular lens implantation provides a continuous, broad range of vision and excellent acuity across all focal distances.