Harnessing diverse transcriptional regulators for natural product discovery in fungi

• Published in: Natural product reports Vol. 37; no. 1; pp. 6 - 16
• Main Authors: Lyu, Hai-Ning, Liu, Hong-Wei, Keller, Nancy P, Yin, Wen-Bing
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 29.01.2020
• Subjects: Biological warfare; Environmental effects; Fungi; Gene clusters; metabolism; Metabolites; Natural products; Organic chemistry; Regulators; Secondary metabolites; transcription (genetics); Transcription activation; Transcription factors; transcriptional activation

Covering: Up to March 2019 Secondary metabolites (SMs) are chemical entities produced by organisms in response to environmental stimuli and as a defense against biological warfare. The production of SMs is controlled by a hierarchical regulatory network involving core factors that orchestrate transc...