Misdiagnosed psychiatric manifestations in a rare disease: a case report of secondary anxiety syndrome in Cushing's disease

Diagnosing and treating secondary psychiatric symptoms with accuracy can be challenging in clinical settings. In this case study, we report on a female patient with Cushing's disease who was misdiagnosed with anxiety disorder during her first psychiatric visit. Following initial ineffective psy...

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Published inFrontiers in psychiatry Vol. 14; p. 1190899
Main Authors Geng, Wenqi, Cui, Lijia, Li, Tao, Liu, Xueqing, Yao, Yong, Hong, Xia, Zhu, Huijuan, Lu, Lin, Wei, Jing
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 27.04.2023
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Summary:Diagnosing and treating secondary psychiatric symptoms with accuracy can be challenging in clinical settings. In this case study, we report on a female patient with Cushing's disease who was misdiagnosed with anxiety disorder during her first psychiatric visit. Following initial ineffective psychiatric intervention, unexplained hypokalemia, and hypothyroidism, the patient visited the endocrinology clinic and was diagnosed with Cushing's disease. During the medical and surgical procedures that followed, high doses of psychotropic medication were continued to treat persisting anxiety. After discharge, the patient developed autonomic dysfunction and impaired consciousness. Upon readmission, serotonin syndrome due to inappropriate psychiatric medication was diagnosed. The management of secondary psychiatric syndromes must be adapted to changes in the patient's primary condition, which necessitates interdisciplinary collaboration in general hospital settings.
Bibliography:Edited by: Vsevolod Konstantinov, Penza State University, Russia
Reviewed by: Yassine Otheman, Sidi Mohamed Ben Abdellah University, Morocco; Akira Monji, Saga University, Japan; Difei Lu, Peking University, China
ISSN:1664-0640
1664-0640
DOI:10.3389/fpsyt.2023.1190899