Personalized medicine progresses

A new approach to personalized drug treatment emerges in a study examining the metabolic profile of rats. The profile, which is a measurement of small molecules such as sugars and amino acids, is used to predict the response to drugs that are toxic to the liver. This study proposes the extension of...

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Bibliographic Details
Published inNature medicine Vol. 12; no. 5; pp. 510 - 511
Main Authors Haselden, John N, Nicholls, Andrew W
Format Journal Article
LanguageEnglish
Published United States Nature Publishing Group 01.05.2006
Subjects
Amino acids
Animals
Clinical outcomes
Drug therapy
Energy Metabolism
Genome, Human
Humans
Life Style
Medicine - methods
Metabolism
Phenotype
Precision medicine
Rats
Rodents
Treatment Outcome
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Summary:A new approach to personalized drug treatment emerges in a study examining the metabolic profile of rats. The profile, which is a measurement of small molecules such as sugars and amino acids, is used to predict the response to drugs that are toxic to the liver. This study proposes the extension of this concept into humans as a way of predicting the outcome of a therapy for a given profile. [PUBLICATION ABSTRACT]
Bibliography:SourceType-Other Sources-1
ObjectType-News-1
content type line 66
ISSN:1078-8956
1546-170X
DOI:10.1038/nm0506-510