Conscious Sedation For In Vitro Fertilization

Objective: To review the principles and practice of the use of conscious sedation for IVF. Design: The pertinent literature was reviewed and recommendations are provided. Result(s): Conscious sedation appears to be the most commonly used method of pain relief for transvaginal retrieval of oocytes. C...

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Bibliographic Details
Published inFertility and sterility Vol. 69; no. 5; pp. 799 - 808
Main Authors Trout, Susan W, Vallerand, April Hazard, Kemmann, Ekkehard
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 01.05.1998
Elsevier Science
Subjects
Anesthesia
Benzodiazepines - pharmacology
Biological and medical sciences
Birth control
conscious sedation
Conscious Sedation - adverse effects
Conscious Sedation - methods
Female
Fertilization in Vitro
Gynecology. Andrology. Obstetrics
Humans
in vitro fertilization
Medical sciences
Monitoring, Physiologic
Propofol - pharmacology
Sterility. Assisted procreation
in vitro fertilization
conscious sedation
Anesthesia
Aspiration
Assisted procreation
Sedation
Germinal cell
In vitro fertilization embryo transfer
Ovary
Analgesia
Transvaginal route
Female genital system
Female
Ovarian follicle
Oocyte
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Summary:Objective: To review the principles and practice of the use of conscious sedation for IVF. Design: The pertinent literature was reviewed and recommendations are provided. Result(s): Conscious sedation appears to be the most commonly used method of pain relief for transvaginal retrieval of oocytes. Conscious sedation does not require the presence of an anesthesiologist and can be done in freestanding clinics. Agents commonly used include opioids in combination with benzodiazepines. This combination minimizes pain, decreases anxiety, and provides sedation and some amnesia. Adjuvants such as promethazine and hydroxyzine can also be used but often are not needed. Conscious sedation is well tolerated by patients and does not require highly specialized equipment. However, there are specific safeguards that should be followed. Only a few toxicity studies have been performed, but they are reassuring because they have not found significant effects on fertilization or cleavage. Conclusion(s): Conscious sedation appears to be a safe and cost-effective method of providing analgesia and anesthesia for transvaginal retrieval of oocytes.
ISSN:0015-0282
1556-5653
DOI:10.1016/S0015-0282(98)00031-4