The expression of fibroblast growth factor-2 and fibroblast growth factor receptor-1 in chondrocytes in synovial chondromatosis of the temporomandibular joint. Report of two cases

• Published in: International journal of oral and maxillofacial surgery Vol. 31; no. 5; pp. 532 - 536
• Main Authors: Sato, J., Segami, N., Suzuki, T., Yoshitake, Y., Nishikawa, K.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 01.10.2002; Elsevier
• Subjects: Biological and medical sciences; Cartilage - pathology; Chondrocytes - pathology; Chondromatosis, Synovial - pathology; Dentistry; Facial bones, jaws, teeth, parodontium: diseases, semeiology; Female; Fibroblast Growth Factor 2 - analysis; fibroblast growth factor receptor-1; fibroblast growth factor-2; Follow-Up Studies; Humans; Hyperplasia; Immunohistochemistry; Joint Loose Bodies - pathology; Mandibular Condyle - pathology; Medical sciences; Metaplasia; Middle Aged; Non tumoral diseases; Otorhinolaryngology. Stomatology; Receptor Protein-Tyrosine Kinases - analysis; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor - analysis; synovial chondromatosis; Synovial Membrane - pathology; temporomandibular joint; Temporomandibular Joint Disorders - pathology; fibroblast growth factor receptor-1; fibroblast growth factor-2; synovial chondromatosis; temporomandibular joint; Human; Immunohistochemistry; Fibroblast growth factor; Chondrocyte; Stomatology; Pathogenesis; Cytokine; Diseases of the osteoarticular system; Temporomandibular joint; Receiver; Case study; Pathology; Chondromatosis; Synovial membrane; Polypeptide; Arthropathy; Adult; Female; Growth factor; Maxillary disease
• ISSN: 0901-5027; 1399-0020
• DOI: 10.1054/ijom.2002.0248

Synovial chondromatosis (SC) is a rare, benign condition characterized by the formation of metaplastic cartilaginous nodules. The expression of fibroblast growth factor-2 (FGF-2) and fibroblast growth factor receptor-1 (FGFR-1) in two cases of SC of the temporomandibular joint (TMJ) were immunohistochemically studied. The possible roles of FGF-2 and FGFR-1 in SC of the TMJ are discussed.