Sustained Consumption of a Decaffeinated Green Coffee Nutraceutical Has Limited Effects on Phenolic Metabolism and Bioavailability in Overweight/Obese Subjects

• Published in: Nutrients Vol. 14; no. 12; p. 2445
• Main Authors: Seguido, Miguel Ángel, Tarradas, Rosa Maria, González-Rámila, Susana, García-Cordero, Joaquín, Sarriá, Beatriz, Bravo-Clemente, Laura, Mateos, Raquel
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 13.06.2022; MDPI
• Subjects: Acids; Bioavailability; Biological Availability; Coffee; Coffee - metabolism; decaffeination; Diet therapy; Dietary Supplements; excretion; feces; Functional foods; Functional foods & nutraceuticals; Health aspects; Humans; intestines; Metabolism; Metabolites; Microbiota; Nutrition research; Obesity; Overweight; Pharmacokinetics; Phenols; Phenols - metabolism; Solvents; Testing; Urine; Weight control; Yogurt; Spain; United States > US; Madrid Spain; pharmacokinetics; hydroxycinnamates; biotransformation pathways; bioavailability; microbial catabolites; green coffee

Knowledge on the bioavailability of coffee (poly)phenols mostly come from single dose postprandial studies. This study aimed at investigating the effects of regularly consuming a green coffee phenolic extract (GCPE) on the bioavailability and metabolism of (poly)phenols. Volunteers with overweight/o...