Growth and the DNA-division sequence in the yeast Saccharomyces cerevisiae
Cells of the yeast S. cerevisiae can be cultured under conditions in which the DNA-division sequence, and not cellular growth, is the rate-limiting feature for cell proliferation. Relief of these limiting conditions, which has been shown to allow accelerated cell division, did not result in increase...
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Published in | Experimental cell research Vol. 157; no. 2; pp. 387 - 396 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Orlando, FL
Elsevier Inc
01.04.1985
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | Cells of the yeast
S. cerevisiae can be cultured under conditions in which the DNA-division sequence, and not cellular growth, is the rate-limiting feature for cell proliferation. Relief of these limiting conditions, which has been shown to allow accelerated cell division, did not result in increased rates of cell mass accumulation during the time of rapid cell division. Moreover, under conditions of constant DNA-division sequence constraint, populations of smaller cells produced by slowing growth with cycloheximide gave rise to large cells when cycloheximide was removed. These observations suggest that in proliferating cells of
S. cerevisiae the DNA-division sequences does not affect cellular growth. |
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Bibliography: | 8613915 F60 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
ISSN: | 0014-4827 1090-2422 |
DOI: | 10.1016/0014-4827(85)90124-7 |