Elevated serum selenium in diabetic children

Twenty-seven diabetic children, 16 girls and 11 boys, 5-18 years of age, with a duration of the disease ranging from 2-15 years, comprised the study group. Thirteen children with a similar age and sex distribution, living in the same area served as healthy controls. All 40 children had a normal grow...

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Bibliographic Details
Published inActa pædiatrica Scandinavica Vol. 73; no. 1; p. 109
Main Authors Gebre-Medhin, M, Ewald, U, Plantin, L O, Tuvemo, T
Format Journal Article
LanguageEnglish
Published Sweden 01.01.1984
Subjects
Adolescent
Blood Glucose - analysis
Child
Child, Preschool
Cholesterol - blood
Diabetes Mellitus, Type 1 - blood
Female
Glycated Hemoglobin A - analysis
Humans
Male
Neutron Activation Analysis
Selenium - blood
Triglycerides - blood
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Summary:Twenty-seven diabetic children, 16 girls and 11 boys, 5-18 years of age, with a duration of the disease ranging from 2-15 years, comprised the study group. Thirteen children with a similar age and sex distribution, living in the same area served as healthy controls. All 40 children had a normal growth pattern. The mean serum selenium concentration in the diabetic children, determined by neutron activation analysis, was 7.4 +/- 0.8 micrograms/100 ml (mean +/- SD) and in the healthy controls 6.5 +/- 0.8 micrograms/100 ml. The difference between the two groups was statistically highly significant (p less than 0.01). Boys and girls in both groups had nearly identical mean serum selenium levels and no correlation was observed between the selenium concentrations and either the age, weight or height of the children or the indicators of diabetic control. The selenium status in diabetic children has not been reported previously. The possibility of elevated serum selenium in diabetic children in response to altered lipid metabolism is discussed.
ISSN:0001-656X
DOI:10.1111/j.1651-2227.1984.tb09907.x