Acinic cell carcinoma of salivary glands: 16 cases with clinicopathologic correlation

Sixteen cases of acinic cell carcinoma (ACC) of salivary glands were studied and their different clinicopathologic aspects were analysed. ACC occurred more frequently in the 5th and 6th decades of life, and was seen exclusively in major salivary glands. The main complaint of the patients was the pre...

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Bibliographic Details
Published inJournal of oral pathology & medicine Vol. 18; no. 7; p. 396
Main Authors Guimaraes, D S, Amaral, A P, Prado, L F, Nascimento, A G
Format Journal Article
LanguageEnglish
Published Denmark 01.08.1989
Subjects
Adult
Aged
Aged, 80 and over
Carcinoma - mortality
Carcinoma - pathology
Carcinoma - surgery
Female
Follow-Up Studies
Humans
Male
Middle Aged
Neoplasm Staging
Salivary Gland Neoplasms - mortality
Salivary Gland Neoplasms - pathology
Salivary Gland Neoplasms - surgery
Survival Rate
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Summary:Sixteen cases of acinic cell carcinoma (ACC) of salivary glands were studied and their different clinicopathologic aspects were analysed. ACC occurred more frequently in the 5th and 6th decades of life, and was seen exclusively in major salivary glands. The main complaint of the patients was the presence of a mass, and the majority of the tumors were Stage III and IV when first seen in our institution. The tumors were divided into three histologic grades based on cellular pleomorphism, mitotic activity, and necrosis. This study showed correlation between prognosis and grading. Other important factors in the prognosis were the type of treatment and the duration of symptoms. Surgical resection with free margins is the treatment of choice.
ISSN:0904-2512
DOI:10.1111/j.1600-0714.1989.tb01571.x