Comparative study of human and rabbit cell infection with cell-free HTLV-I
Infection of human and rabbit cells with cell-free HTLV-I was studied by PCR analysis. Both human and rabbit PBL were infected similarly by cell-free virus of both human and rabbit cell origin. Cells were infected with the cell-free virus without prior treatment and regardless of the concentration o...
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Published in | Journal of medical virology Vol. 39; no. 1; p. 75 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
01.01.1993
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Subjects | |
Online Access | Get more information |
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Summary: | Infection of human and rabbit cells with cell-free HTLV-I was studied by PCR analysis. Both human and rabbit PBL were infected similarly by cell-free virus of both human and rabbit cell origin. Cells were infected with the cell-free virus without prior treatment and regardless of the concentration of the culture supernatant containing the virus. Human and rabbit cell lines were also infected similarly by the cell-free virus, the proviral DNA persisting for more than two months. The culture supernatants of HTLV-I-producing cells could thus be a potential cause of laboratory infections. |
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ISSN: | 0146-6615 |
DOI: | 10.1002/jmv.1890390114 |