Antiphospholipid antibodies in children

Sera from children (n = 173) were tested for antiphospholipid antibodies (aPL) using an enzyme immunoassay detecting IgG anti-cardiolipin antibodies (GPL). Sera from adults (n = 100) were also tested. GPL were detected more frequently and at higher levels in children than in adults. Eighty-two per c...

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Bibliographic Details
Published inActa pædiatrica (Oslo) Vol. 85; no. 5; p. 614
Main Authors Kontiainen, S, Miettinen, A, Seppälä, I, Verkasalo, M, Mäenpää, J
Format Journal Article
LanguageEnglish
Published Norway 01.05.1996
Subjects
Adult
Antibodies, Antiphospholipid - analysis
Antibodies, Antiphospholipid - blood
Child
Humans
Immunoenzyme Techniques
Immunoglobulin G - immunology
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Summary:Sera from children (n = 173) were tested for antiphospholipid antibodies (aPL) using an enzyme immunoassay detecting IgG anti-cardiolipin antibodies (GPL). Sera from adults (n = 100) were also tested. GPL were detected more frequently and at higher levels in children than in adults. Eighty-two per cent of the children and 27% of the adults tested positive (> or = 10 GPL Uml-1) for aPL (p < 0.001). Values of 45 GPLUml-1 or higher were detected in about 5% of the children, and 25 GPLUml-1 or higher in about 5% of the adults. Normal values should be adjusted accordingly.
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1996.tb14098.x