SERS‐Coded Gold Nanorods as a Multifunctional Platform for Densely Multiplexed Near‐Infrared Imaging and Photothermal Heating

Screening nanorods coated with a mixture of SERS active molecules and biocompatible polymer identifies three formulations that may be uniquely distinguished in vivo over a spectral bandwidth of only 6 nm in the near‐infrared (a spectral multiplexing density over an order of magnitude greater than at...

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Bibliographic Details
Published inAdvanced materials (Weinheim) Vol. 21; no. 31; pp. 3175 - 3180
Main Authors von Maltzahn, Geoffrey, Centrone, Andrea, Park, Ji‐Ho, Ramanathan, Renuka, Sailor, Michael J., Hatton, T. Alan, Bhatia, Sangeeta N.
Format Journal Article
LanguageEnglish
Published Weinheim WILEY‐VCH Verlag 21.08.2009
Subjects
cancer
multiplexing
nanorods
nanotechnology
SERRS
SERS
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Summary:Screening nanorods coated with a mixture of SERS active molecules and biocompatible polymer identifies three formulations that may be uniquely distinguished in vivo over a spectral bandwidth of only 6 nm in the near‐infrared (a spectral multiplexing density over an order of magnitude greater than attainable with semiconductor quantum dots, organic fluorochromes, and Raleigh scattering nanoparticle imaging approaches), while providing intense photothermal heating for cancer therapy.
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ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200803464