Post partum nephrotic syndrome in mixed essential cryoglobulinemia

The clinical and histological findings of a patient with mixed essential cryoglobulinemia (MECG) who developed post partum renal failure and the nephrotic syndrome are described. The renal insufficiency responded dramatically to intensive plasma exchange and longer term immunosuppression with associ...

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Bibliographic Details
Published inAustralian and New Zealand journal of medicine Vol. 13; no. 6; p. 633
Main Authors Goodman, G J, Ryan, P F, Sinclair, R A
Format Journal Article
LanguageEnglish
Published Australia 01.12.1983
Subjects
Adult
Combined Modality Therapy
Cryoglobulinemia - immunology
Cryoglobulinemia - pathology
Cyclophosphamide - therapeutic use
Female
Humans
Immunoglobulin A - analysis
Immunoglobulin G - analysis
Immunoglobulin kappa-Chains - analysis
Immunoglobulin M - analysis
Kidney Glomerulus - immunology
Kidney Glomerulus - pathology
Nephrotic Syndrome - immunology
Nephrotic Syndrome - pathology
Paraproteinemias - immunology
Plasma Exchange
Prednisolone - therapeutic use
Pregnancy
Puerperal Disorders - immunology
Puerperal Disorders - pathology
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Summary:The clinical and histological findings of a patient with mixed essential cryoglobulinemia (MECG) who developed post partum renal failure and the nephrotic syndrome are described. The renal insufficiency responded dramatically to intensive plasma exchange and longer term immunosuppression with associated resolution of the renal histological changes. To our knowledge deterioration of renal function in the post partum period has not been previously described in the syndrome of MECG.
ISSN:0004-8291
DOI:10.1111/j.1445-5994.1983.tb02620.x