Prenatal diagnosis and management of fetal anemia secondary to a large chorioangioma

• Published in: Obstetrics and gynecology (New York. 1953) Vol. 102; no. 5; pp. 1185 - 1188
• Main Authors: Hamill, Neil, Rijhsinghani, Asha, Williamson, Roger A, Grant, Stanley
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.11.2003; The American College of Obstetricians and Gynecologists; Elsevier Science
• Subjects: Adult; alpha-Fetoproteins - analysis; Anemia - diagnosis; Anemia - etiology; Anemia - therapy; Biological and medical sciences; Blood Flow Velocity; Diseases of mother, fetus and pregnancy; Female; Fetal Diseases - diagnosis; Fetal Diseases - etiology; Fetal Diseases - therapy; Fetal Hemoglobin - analysis; Gynecology. Andrology. Obstetrics; Hemangioma - complications; Hemangioma - diagnosis; Humans; Medical sciences; Middle Cerebral Artery - diagnostic imaging; Placenta Diseases - complications; Placenta Diseases - diagnosis; Pregnancy; Pregnancy Complications, Neoplastic - diagnosis; Pregnancy. Fetus. Placenta; Prenatal Diagnosis; Ultrasonography, Doppler; Sonography; Doppler ultrasound study; Human; Pregnancy disorders; Anemia; Cardiovascular disease; Hemopathy; Placenta diseases; Blood; Fetal hemoglobin; Vascular disease; Chorioangioma; Assay; Prenatal; Mother; Female; Fetus; Benign neoplasm; Diagnosis
• ISSN: 0029-7844; 1873-233X
• DOI: 10.1016/S0029-7844(03)00576-3

Chorioangiomas are benign vascular tumors of the placenta. Complications occur when their size exceeds 5 cm. We report the use of peak systolic velocity in the middle cerebral artery, fetal hemoglobin levels in maternal circulation, and maternal serum alpha-fetoprotein levels in the diagnosis and management of fetal anemia in a patient with a large placental chorioangioma. Fetal hemoglobin levels in maternal circulation and abrupt elevations of middle cerebral artery peak velocity may be useful in detecting fetal anemia.