In vitro and In vivo study on the effect of autogenous cancellous bone and intramedullary polymethylmethacrylate on allograft construct strength
An in vitro study was performed to compare the effects of augmenting interlocking nails of one of two diameter (5 or 6 mm) with intramedullary polymethylmethacrylate. Subsequently, an in vivo study was performed to compare the effects of augmenting the interlocking nail with five combinations of int...
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Published in | Journal of orthopaedic research Vol. 16; no. 3; pp. 277 - 284 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Hoboken
Wiley Subscription Services, Inc., A Wiley Company
01.05.1998
Blackwell Publishing Ltd |
Subjects | |
Online Access | Get full text |
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Summary: | An in vitro study was performed to compare the effects of augmenting interlocking nails of one of two diameter (5 or 6 mm) with intramedullary polymethylmethacrylate. Subsequently, an in vivo study was performed to compare the effects of augmenting the interlocking nail with five combinations of intramedullary polymethylmethacrylate and autogenous cancellous bone applied to the periosteal surface or within the medullary canal. Dogs were killed 6 months after the procedure for biomechanical evaluation of the femora in axial compression, mediolateral and craniocaudal bending, and torsion. Results from the in vitrostudy at the proximal osteotomy indicated the 6‐mm inteilocking nail with intramedullary polymethylmethacrylate had greater stiffness than the 5‐mm interlocking nail without it (p < 0.05). At the distal osteotomy, regardless of the diameter of the interlocking nail, the addition of intramedullary polymethylmethacrylate increased stiffness (p < 0.05). Results from the in vivo study indicated greater global construct stiffness with an interlocking nail alone, an interlocking nail augmented with intramedullary polymethylmethacrylate and cancellous bone at the periosteal surface, and an interlocking nail augmented with cancellous bone within the medullary canal and at the periosteal surface (p < 0.05). At the osteotomy level, the interlocking nail augmented with intramedullary polymethylmethacrylate and cancellous bone at the periosteal surface had greater stiffness than did an interlocking nail alone or an interlocking nail augmented with either intramedullary polymethylmethacrylate. cancellous bone within the medullary canal, or cancellous bone at the periosteal surface (p < 0.05) but produced the same results as an interlocking nail augmented with cancellous bone within the medullary canal and at the periosteal surface. The results suggest that augmenting interlocking nail fixation with intramedullary polymethylmethacrylate by itself offers no advantage but that acombination of intramedullary polymethylmethacrylate and cancellous bone at the periosteal surface improves structural properties at 6 months. |
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Bibliography: | ark:/67375/WNG-0H32LS0R-P ArticleID:JOR1100160302 istex:8131BC53847DBC97009FB85D136E9E570F56E747 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
ISSN: | 0736-0266 1554-527X |
DOI: | 10.1002/jor.1100160302 |