Advances in Molecular biomarker for early diagnosis of Osteoarthritis
Osteoarthritis (OA) is a chronic degenerative joint disease. The pathogenesis is poorly understood. What is known is that OA is characterized by imbalance in anabolic and catabolic gene expression in articular chondrocytes. This results in bone on bone articulations resulting in impaired mobility an...
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Published in | Biomolecular concepts Vol. 10; no. 1; pp. 111 - 119 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Berlin
De Gruyter
09.08.2019
Walter de Gruyter GmbH |
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Abstract | Osteoarthritis (OA) is a chronic degenerative joint disease. The pathogenesis is poorly understood. What is known is that OA is characterized by imbalance in anabolic and catabolic gene expression in articular chondrocytes. This results in bone on bone articulations resulting in impaired mobility and joint pain. Although the cause of OA is unknown, comorbidities include: aging, obesity, and mechanical stress. Currently the only diagnostic modalities are radiology and physical examination, and early detection is rare. Biomarkers are quantifiable substances, and their presence can be suggestive of a certain phenomenon or disease. Biomarkers are popular for early diagnosis for pathological conditions in the fields of oncology, cardiology, and endocrinology. This review has systematically reviewed the literature about biomarkers in the field of OA, specifically protein, miRNA, and metabolic biomarkers found in the blood, urine, and synovial fluid. |
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AbstractList | Osteoarthritis (OA) is a chronic degenerative joint disease. The pathogenesis is poorly understood. What is known is that OA is characterized by imbalance in anabolic and catabolic gene expression in articular chondrocytes. This results in bone on bone articulations resulting in impaired mobility and joint pain. Although the cause of OA is unknown, comorbidities include: aging, obesity, and mechanical stress. Currently the only diagnostic modalities are radiology and physical examination, and early detection is rare. Biomarkers are quantifiable substances, and their presence can be suggestive of a certain phenomenon or disease. Biomarkers are popular for early diagnosis for pathological conditions in the fields of oncology, cardiology, and endocrinology. This review has systematically reviewed the literature about biomarkers in the field of OA, specifically protein, miRNA, and metabolic biomarkers found in the blood, urine, and synovial fluid. |
Author | Bapat, Santul Kolhe, Ravindra Fulzele, Sadanand Hubbard, Daniel Hunter, Monte Munjal, Akul |
Author_xml | – sequence: 1 givenname: Akul surname: Munjal fullname: Munjal, Akul organization: Department of Orthopedics, Augusta University, Augusta, GA – sequence: 2 givenname: Santul surname: Bapat fullname: Bapat, Santul organization: Department of Orthopedics, Augusta University, Augusta, GA – sequence: 3 givenname: Daniel surname: Hubbard fullname: Hubbard, Daniel organization: Department of Orthopedics, Augusta University, Augusta, GA – sequence: 4 givenname: Monte surname: Hunter fullname: Hunter, Monte organization: Department of Orthopedics, Augusta University, Augusta, GA – sequence: 5 givenname: Ravindra surname: Kolhe fullname: Kolhe, Ravindra organization: Department of Pathology, Augusta University, Augusta, GA – sequence: 6 givenname: Sadanand surname: Fulzele fullname: Fulzele, Sadanand email: sfulzele@augusta.edu organization: Institute of Regenerative and Reparative medicine, Augusta University, Augusta, GA |
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Cites_doi | 10.1080/03009740701250785 10.1053/joca.2002.0829 10.3892/mmr.2015.4121 10.2174/138920210793175895 10.1097/MD.0000000000007593 10.1126/science.289.5484.1504 10.1093/rheumatology/kew427 10.1007/s00403-014-1472-8 10.1073/pnas.1208916109 10.1016/j.acthis.2014.03.011 10.1002/art.23654 10.1111/j.1365-2613.2010.00707.x 10.1016/j.jaci.2010.11.050 10.3346/jkms.2015.30.9.1246 10.1016/j.joca.2006.02.015 10.1007/s10555-006-9005-3 10.1517/14728222.7.2.277 10.12659/MSM.906838 10.1194/jlr.M001099 10.1038/s41598-017-03616-w 10.3899/jrheum.150917 10.3892/ol.2014.2575 10.1002/jcla.22648 10.1111/j.1601-6343.2004.00308.x 10.1016/S1567-133X(03)00084-X 10.1080/14789450.2016.1190651 10.1136/ard.16.4.494 10.1097/COH.0b013e32833ed177 10.1007/s00394-018-1632-2 10.1016/j.joca.2015.10.013 10.1111/sms.12290 10.1038/onc.2017.109 10.1002/jor.22324 10.1002/(SICI)1520-670X(1998)11:2/3<119::AID-JTRA5>3.0.CO;2-3 10.1016/j.joca.2014.01.003 10.1042/CS20110496 10.3390/ijms20030511 10.12659/MSM.908219 10.1093/bmb/lds038 10.1073/pnas.92.16.7257 10.2302/kjm.52.1 10.3892/mmr.2017.7251 10.1074/jbc.M607999200 10.1016/j.dental.2010.07.006 10.1186/ar3216 10.1016/j.joca.2016.04.019 10.1097/MD.0000000000003585 10.1152/ajpcell.00279.2015 10.1136/jcp.55.8.561 |
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References | Yang, F; Hu, A; Zhao, D; Guo, L; Yang, L; Wang, B (j_bmc-2019-0014_ref_070) 2015; 12 Ehlermann, J; Weber, S; Pfisterer, P; Schorle, H (j_bmc-2019-0014_ref_017) 2003; 3 Yu, Z; Kastenmüller, G; He, Y; Belcredi, P; Möller, G; Prehn, C (j_bmc-2019-0014_ref_011) 2010; 6 Kurowska-Stolarska, M; Alivernini, S; Ballantine, LE; Asquith, DL; Millar, NL (j_bmc-2019-0014_ref_035) 2011; 108 Doss, F; Menard, J; Hauschild, M; Kreutzer, HJ; Mittlmeier, T; Müller-Steinhardt, M (j_bmc-2019-0014_ref_051) 2007; 36 Poole, AR; Ha, N; Bourdon, S; Sayre, EC; Guermazi, A; Cibere, J (j_bmc-2019-0014_ref_042) 2016; 43 Chu, H; Xu, ZM; Yu, H; Zhu, KJ; Huang, H (j_bmc-2019-0014_ref_055) 2014; 14 Liu, C; Tang, J (j_bmc-2019-0014_ref_058) 2014; 8 Ntoumou, E; Tzetis, M; Braoudaki, M; Lambrou, G; Poulou, M; Malizos, K (j_bmc-2019-0014_ref_031) 2017; 127 Bellucci, F; Meini, S; Cucchi, P; Catalani, C; Nizzardo, A; Riva, A (j_bmc-2019-0014_ref_066) 2013; 21 Lafont, JE. (j_bmc-2019-0014_ref_053) 2010; 91 Honorati, MC; Bovara, M; Cattini, L; Piacentini, A; Facchini, A (j_bmc-2019-0014_ref_028) 2002; 10 Yingsong, L; Peng, H; Meng, Z; Wei, M (j_bmc-2019-0014_ref_046) 2015; 21 Huang, G; Hua, S; Yang, T; Ma, J; Yu, W; Chen, X (j_bmc-2019-0014_ref_002) 2018; 15 Zheng, WD1; Zhou, FL; Lin, N; Liu, J (j_bmc-2019-0014_ref_029) 2018; 22 Zharkova, O; Celhar, T; Cravens, PD; Satterthwaite, AB; Fairhurst, AM; Davis, LS (j_bmc-2019-0014_ref_013) 2017; 56 Silvestri, T; Pulsatelli, L; Dolzani, P; Facchini, A; Meliconi, R (j_bmc-2019-0014_ref_015) 2006; 14 Nandhu, MS; Kwiatkowska, A; Bhaskaran, V; Hayes, J; Hu, B; Viapiano, MS (j_bmc-2019-0014_ref_016) 2017; 36 Kolhe, R; Hunter, M; Liu, S; Jadeja, R; Pundkar, C; Mondal, A (j_bmc-2019-0014_ref_004) 2017; 7 Ko, JY; Lee, MS; Lian, WS; Weng, WT; Sun, YC; Chen, YS (j_bmc-2019-0014_ref_071) 2017; 7 Szychlinska, MA; Castrogiovanni, P; Trovato, FM; Nsir, H; Zarrouk, M; Lo, Furno D (j_bmc-2019-0014_ref_063) 2019; 58 Wan, L; Zhao, Q; Niu, G; Xiang, T; Ding, C; Wang, S (j_bmc-2019-0014_ref_027) 2018; 16 Yamaguchi, M. (j_bmc-2019-0014_ref_037) 1998; 11 Balkwill, F. (j_bmc-2019-0014_ref_057) 2006; 25 Tezvergil-Mutluay, A; Agee, KA; Hoshika, T; Carrilho, M; Breschi, L; Tjäderhane, L (j_bmc-2019-0014_ref_039) 2010; 26 Akdis, M; Burgler, S; Crameri, R; Eiwegger, T; Fujita, H; Gomez, E (j_bmc-2019-0014_ref_012) 2011; 127 Golias, Ch; Charalabopoulos, A; Stagikas, D; Charalabopoulos, K; Batistatou, A (j_bmc-2019-0014_ref_064) 2007; 11 Staikova, ND; Kuzmanova, SI; Solakov, PT (j_bmc-2019-0014_ref_073) 2003; 45 Kong, R; Gao, J; Si, Y; Zhao, D (j_bmc-2019-0014_ref_032) 2017; 9 McAlindon, TE; Bannuru, RR; Sullivan, MC; Arden, NK; Berenbaum, F; Bierma-Zeinstra, SM (j_bmc-2019-0014_ref_007) 2014; 22 Runhaar, J; Sanchez, C; Taralla, S; Henrotin, Y; Bierma-Zeinstra, SM (j_bmc-2019-0014_ref_018) 2016; 24 Chen, Y; Wang, X; Yang, M; Ruan, W; Wei, W; Gu, D (j_bmc-2019-0014_ref_069) 2018; 24 Kim, MJ; Kim, HJ; Hong, YH; Lee, CK; Kim, YW; Shon, OJ (j_bmc-2019-0014_ref_021) 2015; 30 Musumeci, G; Trovato, FM; Loreto, C; Leonardi, R; Szychlinska, MA; Castorina, S (j_bmc-2019-0014_ref_062) 2014; 116 Teitelbaum, S. (j_bmc-2019-0014_ref_049) 2000; 289 Musumeci, G; Loreto, C; Imbesi, R; Trovato, FM; Di, Giunta A; Lombardo, C (j_bmc-2019-0014_ref_006) 2014; 29 Kellgren, JH; Lawrence, JS (j_bmc-2019-0014_ref_008) 1957; 16 Elsaid, KA; Fleming, BC; Oksendahl, HL; Machan, JT; Fadale, PD; Hulstyn, MJ (j_bmc-2019-0014_ref_060) 2009; 58 Xue, M; Qiqige, C; Zhang, Q; Zhao, H; Su, L; Sun, P (j_bmc-2019-0014_ref_056) 2018; 24 Miyamoto, T; Suda, T (j_bmc-2019-0014_ref_050) 2003; 52 Zhen, EY; Brittain, IJ; Laska, DA; Mitchell, PG; Sumer, EU; Karsdal, MA (j_bmc-2019-0014_ref_041) 2008; 58 Yang, Y; Xiang, Z; Ertl, HC; Wilson, JM (j_bmc-2019-0014_ref_072) 1995; 92 Meadows, C; Morré, DJ; Morré, DM; Draelos, ZD; Kern, D (j_bmc-2019-0014_ref_020) 2014; 306 Litwic, A; Edwards, MH; Dennison, EM; Cooper, C (j_bmc-2019-0014_ref_003) 2013; 105 Iversen, M; Lyn, Price L; von, Heideken J; Harvey, W; Wang, Ch (j_bmc-2019-0014_ref_009) 2016; 17 Dong, Z; Jiang, H; Jian, X; Zhang, W (j_bmc-2019-0014_ref_034) 2019; 33 Tseng, S; Hari, Reddi A; Di, Cesare P (j_bmc-2019-0014_ref_024) 2009; 4 Musumeci, G; Castrogiovanni, P; Trovato, FM; Imbesi, R; Giunta, S; Szychlinska, MA (j_bmc-2019-0014_ref_005) 2015; 25 Van, Heerebeek L; Meischi, C; Stooker, W; Meijer, CJLM; Niessen, HWM; Roos, D (j_bmc-2019-0014_ref_019) 2002; 55 Shen, G. (j_bmc-2019-0014_ref_022) 2005; 8 Tseng, W; Lu, J; Bishop, G; Watson, A; Sage, A; Demer, L; Demer; Tintut, Y. (j_bmc-2019-0014_ref_047) 2010; 51 Koichi, Murata HY; Shimei, Tanida; Masahiro, Ishikawa; Kohei, Nishitani; Hiromu, Ito; Takashi, Nakamura (j_bmc-2019-0014_ref_067) 2009; 12 Verma, P; Dalal, K (j_bmc-2019-0014_ref_025) 2013; 31 Zhu, S; Qian, Y (j_bmc-2019-0014_ref_045) 2012; 122 Larsson, S; Englund, M; Struglics, A; Lohmander, LS (j_bmc-2019-0014_ref_059) 2015; 21 Jin, W; Dong, C (j_bmc-2019-0014_ref_044) 2013; 2 Howl, J; Payne, SJ (j_bmc-2019-0014_ref_065) 2003; 7 Catterall, JB; Stabler, TV; Flannery, CR; Kraus, VB (j_bmc-2019-0014_ref_043) 2010; 12 Yoshitake, F; Itoh, S; Narita, H; Ishihara, K; Ebisu, S (j_bmc-2019-0014_ref_048) 2008; 283 Shan, Y; Qi, C; Liu, Y; Gao, H; Zhao, D; Jiang, Y (j_bmc-2019-0014_ref_014) 2006; 15 Szychlinska, MA; Leonardi, R; Al-Qahtani, M; Mobasheri, A; Musumeci, G (j_bmc-2019-0014_ref_061) 2016; 59 Boonrungsiman, S; Gentleman, E; Carzaniga, R; Evans, ND; McComb, DW; Porter, AE (j_bmc-2019-0014_ref_038) 2012; 109 Xu, C; Gu, K; Yasen, Y; Hou, Y (j_bmc-2019-0014_ref_033) 2016; 95 Strimbu, K; Tavel, J (j_bmc-2019-0014_ref_010) 2010; 5 Harpole, M; Davis, J; Espina, V (j_bmc-2019-0014_ref_036) 2016; 13 Hubbi, ME; Semenza, GL (j_bmc-2019-0014_ref_054) 2015; 309 Li, H; Bai, B; Wang, J; Xu, Z; Yan, S; Liu, G (j_bmc-2019-0014_ref_030) 2017; 16 Xin, L; Wu, Z; Qu, Q; Wang, R; Tang, J; Chen, L (j_bmc-2019-0014_ref_040) 2017; 96 He, Y; Siebuhr, AS; Brandt-Hansen, NU; Wang, J; Su, D; Zheng, Q (j_bmc-2019-0014_ref_023) 2014; 15 Li, YH; Tavallaee, G; Tokar, T; Nakamura, A; Sundararajan, K; Weston, A (j_bmc-2019-0014_ref_068) 2016; 24 Macfarlane, LA; Murphy, PR (j_bmc-2019-0014_ref_026) 2010; 11 Castrogiovanni, P; Di, Rosa M; Ravalli, S; Castorina, A; Guglielmino, C; Imbesi, R (j_bmc-2019-0014_ref_052) 2019; 20 (ref1391) 2009; 12 (ref1091) 1998; 11 (ref1131) 2008; 58 (ref1331) 2016; 59 (ref561) 2006; 25 (ref611) 2014; 116 (ref231) 2009; 4 (ref481) 2000; 289 (ref891) 2003; 3 (ref491) 2003; 52 (ref621) 2019; 58 (ref1281) 2018; 24 (ref801) 1957; 16 (ref1201) 2008; 283 (ref1451) 2003; 45 (ref1081) 2016; 13 (ref651) 2013; 21 (ref511) 2019; 20 (ref1051) 2016; 95 (ref61) 2014; 22 (ref1161) 2013; 2 (ref211) 2005; 8 (ref131) 2006; 15 (ref1251) 2010; 91 (ref1411) 2018; 24 (ref851) 2017; 56 (ref451) 2015; 21 (ref71) 1957; 16 (ref881) 2017; 36 (ref1001) 2002; 10 (ref181) 2002; 55 (ref101) 2010; 6 (ref411) 2016; 43 (ref1291) 2006; 25 (ref841) 2011; 127 (ref41) 2015; 25 (ref761) 2017; 7 (ref1121) 2017; 96 (ref1211) 2000; 289 (ref81) 2016; 17 (ref371) 2012; 109 (ref1071) 2011; 108 (ref221) 2014; 15 (ref391) 2017; 96 (ref751) 2013; 105 (ref1041) 2017; 9 (ref911) 2002; 55 (ref1351) 2019; 58 (ref351) 2016; 13 (ref951) 2014; 15 (ref401) 2008; 58 (ref1421) 2015; 12 (ref1191) 2010; 51 (ref381) 2010; 26 (ref151) 2017; 36 (ref691) 2015; 12 (ref471) 2008; 283 (ref1371) 2003; 7 (ref861) 2006; 15 (ref771) 2015; 25 (ref321) 2016; 95 (ref971) 2013; 31 (ref901) 2016; 24 (ref581) 2015; 21 (ref921) 2014; 306 (ref331) 2019; 33 (ref1221) 2003; 52 (ref541) 2014; 14 (ref1231) 2007; 36 (ref1311) 2015; 21 (ref1021) 2017; 16 (ref1141) 2016; 43 (ref291) 2017; 16 (ref121) 2017; 56 (ref811) 2016; 17 (ref871) 2006; 14 (ref1171) 2012; 122 (ref91) 2010; 5 (ref1361) 2007; 11 (ref821) 2010; 5 (ref21) 2013; 105 (ref51) 2014; 29 (ref1031) 2017; 127 (ref1101) 2012; 109 (ref501) 2007; 36 (ref981) 2010; 11 (ref711) 1995; 92 (ref531) 2015; 309 (ref191) 2014; 306 (ref421) 2010; 12 (ref31) 2017; 7 (ref1111) 2010; 26 (ref301) 2017; 127 (ref111) 2011; 127 (ref461) 2010; 51 (ref141) 2006; 14 (ref1261) 2015; 309 (ref631) 2007; 11 (ref1271) 2014; 14 (ref931) 2015; 30 (ref251) 2010; 11 (ref741) 2018; 15 (ref641) 2003; 7 (ref701) 2017; 7 (ref601) 2016; 59 (ref261) 2018; 16 (ref311) 2017; 9 (ref661) 2009; 12 (ref831) 2010; 6 (ref1441) 1995; 92 (ref591) 2009; 58 (ref361) 1998; 11 (ref281) 2018; 22 (ref271) 2002; 10 (ref161) 2003; 3 (ref941) 2005; 8 (ref1301) 2014; 8 (ref1011) 2018; 22 (ref1151) 2010; 12 (ref1381) 2013; 21 (ref1061) 2019; 33 (ref991) 2018; 16 (ref441) 2012; 122 (ref171) 2016; 24 (ref241) 2013; 31 (ref721) 2003; 45 (ref681) 2018; 24 (ref1321) 2009; 58 (ref431) 2013; 2 (ref521) 2010; 91 (ref961) 2009; 4 (ref341) 2011; 108 (ref571) 2014; 8 (ref1401) 2016; 24 (ref551) 2018; 24 (ref1341) 2014; 116 (ref781) 2014; 29 (ref1241) 2019; 20 (ref1181) 2015; 21 (ref671) 2016; 24 (ref11) 2018; 15 (ref791) 2014; 22 (ref1431) 2017; 7 (ref201) 2015; 30 |
References_xml | – volume: 56 start-page: i55 issue: 1 year: 2017 end-page: i66 ident: j_bmc-2019-0014_ref_013 article-title: Pathways leading to an immunological disease: systemic lupus erythematosus publication-title: Rheumatology contributor: fullname: Zharkova, O; Celhar, T; Cravens, PD; Satterthwaite, AB; Fairhurst, AM; Davis, LS – volume: 55 start-page: 561 issue: 7 year: 2002 end-page: 568 ident: j_bmc-2019-0014_ref_019 article-title: NADPH oxidase(s): new source(s) of reactive oxygen species in the vascular system?’ publication-title: Journal of Clinical Pathology contributor: fullname: Van, Heerebeek L; Meischi, C; Stooker, W; Meijer, CJLM; Niessen, HWM; Roos, D – volume: 309 start-page: C775 issue: 12 year: 2015 end-page: 82 ident: j_bmc-2019-0014_ref_054 article-title: Regulation of Cell Proliferation by Hypoxia-Inducible Factors publication-title: American Physiological Society contributor: fullname: Hubbi, ME; Semenza, GL – volume: 22 start-page: 5424 year: 2018 end-page: 5428 ident: j_bmc-2019-0014_ref_029 article-title: Investigation for the role of CTX-III and microRNA-98 in diagnosis and treatment of osteoarthritis publication-title: European Review for Medical and Pharmacological Sciences contributor: fullname: Zheng, WD1; Zhou, FL; Lin, N; Liu, J – volume: 109 start-page: 14170 issue: 35 year: 2012 end-page: 5 ident: j_bmc-2019-0014_ref_038 article-title: The role of intracellular calcium phosphate in osteoblast-mediated bone apatite formation publication-title: PNAS contributor: fullname: Boonrungsiman, S; Gentleman, E; Carzaniga, R; Evans, ND; McComb, DW; Porter, AE – volume: 51 start-page: 1010 issue: 1010 year: 2010 end-page: 1016 ident: j_bmc-2019-0014_ref_047 article-title: Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids publication-title: Journal of Lipid Research contributor: fullname: Tseng, W; Lu, J; Bishop, G; Watson, A; Sage, A; Demer, L; Demer; Tintut, Y. – volume: 122 start-page: 487 issue: 11 year: 2012 end-page: 511 ident: j_bmc-2019-0014_ref_045 article-title: IL-17/IL-17 receptor system in autoimmune disease: mechanisms and therapeutic potential publication-title: Clinical Science contributor: fullname: Zhu, S; Qian, Y – volume: 283 start-page: 11535 issue: 5 year: 2008 end-page: 40 ident: j_bmc-2019-0014_ref_048 article-title: Interleukin-6 Directly Inhibits Osteoclast Differentiation by Suppressing Receptor Activator of NF-κB Signaling Pathways publication-title: Journal of Biological Chemistry contributor: fullname: Yoshitake, F; Itoh, S; Narita, H; Ishihara, K; Ebisu, S – volume: 29 start-page: 707 issue: 6 year: 2014 end-page: 19 ident: j_bmc-2019-0014_ref_006 article-title: Advantages of exercise in rehabilitation, treatment and prevention of altered morphological features in knee osteoarthritis publication-title: A narrative review. Histology And Histopathology contributor: fullname: Musumeci, G; Loreto, C; Imbesi, R; Trovato, FM; Di, Giunta A; Lombardo, C – volume: 25 start-page: e222 issue: 3 year: 2015 end-page: 30 ident: j_bmc-2019-0014_ref_005 article-title: Physical activity ameliorates cartilage degeneration in a rat model of aging: a study on lubricin expression publication-title: Scandinavian Journal of Medicine and Science In Sports contributor: fullname: Musumeci, G; Castrogiovanni, P; Trovato, FM; Imbesi, R; Giunta, S; Szychlinska, MA – volume: 16 start-page: 3419 issue: 4 year: 2018 end-page: 3424 ident: j_bmc-2019-0014_ref_027 article-title: Plasma miR-136 can be used to screen patients with knee osteoarthritis from healthy controls by targeting IL-17 publication-title: Experimental and Therapeutic Medicine contributor: fullname: Wan, L; Zhao, Q; Niu, G; Xiang, T; Ding, C; Wang, S – volume: 17 start-page: 12 issue: 273 year: 2016 ident: j_bmc-2019-0014_ref_009 article-title: Physical examination findings and their relationship with performance-based function in adults with knee osteoarthritis publication-title: BioMed Central Musculoskeletal Disorders contributor: fullname: Iversen, M; Lyn, Price L; von, Heideken J; Harvey, W; Wang, Ch – volume: 7 start-page: 3584 issue: 1 year: 2017 ident: j_bmc-2019-0014_ref_071 article-title: MicroRNA-29a Counteracts Synovitis in Knee Osteoarthritis Pathogenesis by Targeting VEGF publication-title: Scientific Reports contributor: fullname: Ko, JY; Lee, MS; Lian, WS; Weng, WT; Sun, YC; Chen, YS – volume: 33 start-page: e22648 issue: 1 year: 2019 ident: j_bmc-2019-0014_ref_034 article-title: Change of miRNA expression profiles in patients with knee osteoarthritis before and after celecoxib treatment publication-title: Journal of Clinical Laboratory Analysis contributor: fullname: Dong, Z; Jiang, H; Jian, X; Zhang, W – volume: 15 start-page: 1095 issue: 3 year: 2006 end-page: 1102 ident: j_bmc-2019-0014_ref_014 article-title: Increased frequency of peripheral blood follicular helper T cells and elevated serum IL‑21 levels in patients with knee osteoarthritis publication-title: Molecular Medicine Reports contributor: fullname: Shan, Y; Qi, C; Liu, Y; Gao, H; Zhao, D; Jiang, Y – volume: 22 start-page: 363 issue: 25 year: 2014 end-page: 388 ident: j_bmc-2019-0014_ref_007 article-title: OARSI guidelines for the nonsurgical management of knee osteoarthritis publication-title: Osteoarthritis Cartilage contributor: fullname: McAlindon, TE; Bannuru, RR; Sullivan, MC; Arden, NK; Berenbaum, F; Bierma-Zeinstra, SM – volume: 21 start-page: 6 issue: 11 year: 2013 ident: j_bmc-2019-0014_ref_066 article-title: Synovial fluid levels of bradykinin correlate with biochemical markers for cartilage degradation and inflammation in knee osteoarthritis publication-title: Osteoarthritis and Cartilage contributor: fullname: Bellucci, F; Meini, S; Cucchi, P; Catalani, C; Nizzardo, A; Riva, A – volume: 21 start-page: 1732 year: 2015 end-page: 1736 ident: j_bmc-2019-0014_ref_046 article-title: Correlation of IL-17 Level in Synovia and Severity of Knee Osteoarthritis publication-title: International Medical Journal of Experimental and Clinical Research contributor: fullname: Yingsong, L; Peng, H; Meng, Z; Wei, M – volume: 12 start-page: 6199 issue: 4 year: 2015 end-page: 206 ident: j_bmc-2019-0014_ref_070 article-title: An insertion/deletion polymorphism at the microRNA-122 binding site in the interleukin-1α 3’-untranslated region is associated with a risk for osteoarthritis publication-title: Molecular Medicine Reports contributor: fullname: Yang, F; Hu, A; Zhao, D; Guo, L; Yang, L; Wang, B – volume: 2 start-page: e60 issue: 60 year: 2013 ident: j_bmc-2019-0014_ref_044 article-title: IL-17 Cytokines in Immunity and Inflammation publication-title: Emerging Microbes and Infections contributor: fullname: Jin, W; Dong, C – volume: 26 start-page: 1059 issue: 11 year: 2010 end-page: 67 ident: j_bmc-2019-0014_ref_039 article-title: The requirement of zinc and calcium ions for functional MMP activity in demineralized dentin matrices publication-title: Dental Materials contributor: fullname: Tezvergil-Mutluay, A; Agee, KA; Hoshika, T; Carrilho, M; Breschi, L; Tjäderhane, L – volume: 31 start-page: 999 issue: 7 year: 2013 end-page: 1006 ident: j_bmc-2019-0014_ref_025 article-title: Serum cartilage oligomeric matrix protein (COMP) in knee osteoarthritis: A novel diagnostic and prognostic biomarker publication-title: Journal of Orthopaedic Research contributor: fullname: Verma, P; Dalal, K – volume: 14 start-page: 717 issue: 7 year: 2006 end-page: 9 ident: j_bmc-2019-0014_ref_015 article-title: Elevated Serum levels of Soluble Interleukin-4 receptor publication-title: Osteoarthritis and Cartilage contributor: fullname: Silvestri, T; Pulsatelli, L; Dolzani, P; Facchini, A; Meliconi, R – volume: 24 start-page: 5292 year: 2018 end-page: 5300 ident: j_bmc-2019-0014_ref_069 article-title: miR-145-5p Increases Osteoclast Numbers In Vitro and Aggravates Bone Erosion in Collagen-Induced Arthritis by Targeting Osteoprotegerin publication-title: Medical Science Monitor contributor: fullname: Chen, Y; Wang, X; Yang, M; Ruan, W; Wei, W; Gu, D – volume: 15 start-page: 6 issue: 3 year: 2018 ident: j_bmc-2019-0014_ref_002 article-title: Platelet-rich plasma shows beneficial effects for patients with knee osteoarthritis by suppressing inflammatory factors publication-title: Journal of Experimental and Therapeutic Medicine contributor: fullname: Huang, G; Hua, S; Yang, T; Ma, J; Yu, W; Chen, X – volume: 289 start-page: 1504 issue: 5484 year: 2000 end-page: 8 ident: j_bmc-2019-0014_ref_049 article-title: Bone Resorption by Osteoclasts publication-title: Science contributor: fullname: Teitelbaum, S. – volume: 58 start-page: 565 issue: 2 year: 2019 end-page: 581 ident: j_bmc-2019-0014_ref_063 article-title: Physical activity and Mediterranean diet based on olive tree phenolic compounds from two different geographical areas have protective effects on early osteoarthritis, muscle atrophy and hepatic steatosis publication-title: European Journal of Nutrition contributor: fullname: Szychlinska, MA; Castrogiovanni, P; Trovato, FM; Nsir, H; Zarrouk, M; Lo, Furno D – volume: 96 start-page: e7593 issue: 32 year: 2017 ident: j_bmc-2019-0014_ref_040 article-title: Comparative study of CTX-II, Zn2+, and Ca2+ from the urine for knee osteoarthritis patients and healthy individuals publication-title: Medicine contributor: fullname: Xin, L; Wu, Z; Qu, Q; Wang, R; Tang, J; Chen, L – volume: 12 start-page: R229 year: 2010 ident: j_bmc-2019-0014_ref_043 article-title: Changes in Serum and Synovial Fluid Biomarkers after Acute Injury publication-title: Arthritis Research and Therapy contributor: fullname: Catterall, JB; Stabler, TV; Flannery, CR; Kraus, VB – volume: 91 start-page: 99 issue: 2 year: 2010 end-page: 106 ident: j_bmc-2019-0014_ref_053 article-title: Lack of Oxygen in Articular Cartilage: Consequences For Chondrocyte Biology publication-title: International Journal of Experimental Pathology contributor: fullname: Lafont, JE. – volume: 24 start-page: 1577 issue: 9 year: 2016 end-page: 86 ident: j_bmc-2019-0014_ref_068 article-title: Identification of synovial fluid microRNA signature in knee osteoarthritis: differentiating early- and late-stage knee osteoarthritis publication-title: Osteoarthritis and Cartilage contributor: fullname: Li, YH; Tavallaee, G; Tokar, T; Nakamura, A; Sundararajan, K; Weston, A – volume: 45 start-page: 35 issue: 3 year: 2003 end-page: 42 ident: j_bmc-2019-0014_ref_073 article-title: Serologic markers of early rheumatoid arthritis publication-title: Folia Medica contributor: fullname: Staikova, ND; Kuzmanova, SI; Solakov, PT – volume: 127 start-page: 15 issue: 9 year: 2017 ident: j_bmc-2019-0014_ref_031 article-title: Anastasopoulou and A. Tsezou. Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes publication-title: Clinical Epigenetics contributor: fullname: Ntoumou, E; Tzetis, M; Braoudaki, M; Lambrou, G; Poulou, M; Malizos, K – volume: 116 start-page: 965 issue: 5 year: 2014 end-page: 72 ident: j_bmc-2019-0014_ref_062 article-title: Lubricin expression in human osteoarthritic knee meniscus and synovial fluid: A morphological, immunohistochemical and biochemical study publication-title: Acta Histochemica contributor: fullname: Musumeci, G; Trovato, FM; Loreto, C; Leonardi, R; Szychlinska, MA; Castorina, S – volume: 21 start-page: 1906 issue: 11 year: 2015 end-page: 14 ident: j_bmc-2019-0014_ref_059 article-title: Interleukin-6 and Tumor Necrosis Factor Alpha in Synovial Fluid Are Associated with Progression of Radiographic Knee Osteoarthritis in Subjects with Previous Meniscectomy publication-title: Osteoarthritis and Cartilage contributor: fullname: Larsson, S; Englund, M; Struglics, A; Lohmander, LS – volume: 11 start-page: 119 issue: 2 year: 1998 end-page: 135 ident: j_bmc-2019-0014_ref_037 article-title: Role of Zinc in Bone Formation and Bone Resorption publication-title: The Journal of Trace Elements in Experimental Medicine contributor: fullname: Yamaguchi, M. – volume: 127 start-page: 701 issue: 3 year: 2011 end-page: 721 ident: j_bmc-2019-0014_ref_012 article-title: Interleukins, from 1 to 37, and interferon-g: Receptors, functions, and roles in diseases publication-title: The Journal of Allergy and Clinical Immunology contributor: fullname: Akdis, M; Burgler, S; Crameri, R; Eiwegger, T; Fujita, H; Gomez, E – volume: 95 start-page: e3585 issue: 20 year: 2016 ident: j_bmc-2019-0014_ref_033 article-title: Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials publication-title: Medicine contributor: fullname: Xu, C; Gu, K; Yasen, Y; Hou, Y – volume: 58 start-page: 2420 issue: 8 year: 2008 end-page: 31 ident: j_bmc-2019-0014_ref_041 article-title: Characterization of Metalloprotease Cleavage Products of Human Articular Cartilage publication-title: Arthritis and Rheumatism contributor: fullname: Zhen, EY; Brittain, IJ; Laska, DA; Mitchell, PG; Sumer, EU; Karsdal, MA – volume: 12 start-page: 1774 issue: 86 year: 2009 end-page: 80 ident: j_bmc-2019-0014_ref_067 article-title: Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis publication-title: Arthritis Research and Therapy contributor: fullname: Koichi, Murata HY; Shimei, Tanida; Masahiro, Ishikawa; Kohei, Nishitani; Hiromu, Ito; Takashi, Nakamura – volume: 36 start-page: 4875 issue: 34 year: 2017 end-page: 4886 ident: j_bmc-2019-0014_ref_016 article-title: Tumor-derived fibulin-3 activates pro-invasive NF-kappa B signaling in glioblastoma cells and their microenvironment publication-title: Oncogene contributor: fullname: Nandhu, MS; Kwiatkowska, A; Bhaskaran, V; Hayes, J; Hu, B; Viapiano, MS – volume: 59 start-page: 149 issue: 3 year: 2016 end-page: 156 ident: j_bmc-2019-0014_ref_061 article-title: Altered joint tribology in osteoarthritis: Reduced lubricin synthesis due to the inflammatory process publication-title: New horizons for therapeutic approaches. Anals of Physical and Rehabilitaiton Medicine contributor: fullname: Szychlinska, MA; Leonardi, R; Al-Qahtani, M; Mobasheri, A; Musumeci, G – volume: 14 start-page: 10529 issue: 4 year: 2014 end-page: 36 ident: j_bmc-2019-0014_ref_055 article-title: Association Between Hypoxia-Inducible Factor-1a Levels in Serum and Synovial Fluid with the Radiographic Severity of Knee Osteoarthritis publication-title: Genetic Molecular Research contributor: fullname: Chu, H; Xu, ZM; Yu, H; Zhu, KJ; Huang, H – volume: 306 start-page: 645 issue: 7 year: 2014 end-page: 52 ident: j_bmc-2019-0014_ref_020 article-title: Age-related NADH oxidase (arNOX)-catalyzed oxidative damage to skin proteins publication-title: Archives of Dermatological Research contributor: fullname: Meadows, C; Morré, DJ; Morré, DM; Draelos, ZD; Kern, D – volume: 13 start-page: 609 issue: 6 year: 2016 end-page: 26 ident: j_bmc-2019-0014_ref_036 article-title: Current State of the Art for Enhancing Urine Biomarker Discovery Volume 13 publication-title: Expert Review Proteomics contributor: fullname: Harpole, M; Davis, J; Espina, V – volume: 11 start-page: 537 issue: 7 year: 2010 end-page: 67 ident: j_bmc-2019-0014_ref_026 article-title: MicroRNA: Biogenesis, Function and Role in Cancer publication-title: Current Genomics contributor: fullname: Macfarlane, LA; Murphy, PR – volume: 4 start-page: 33 year: 2009 end-page: 44 ident: j_bmc-2019-0014_ref_024 article-title: Cartilage Oligomeric Matrix Protein: A biomarker of Arthritis publication-title: Biomarker Insights contributor: fullname: Tseng, S; Hari, Reddi A; Di, Cesare P – volume: 58 start-page: 1707 issue: 6 year: 2009 end-page: 15 ident: j_bmc-2019-0014_ref_060 article-title: Decreased Lubricin Concentrations and Markers of Joint Inflammation in Synovial Fluids from Patients with Anterior Cruciate Ligament Injury publication-title: Arthritis and Rheumatism contributor: fullname: Elsaid, KA; Fleming, BC; Oksendahl, HL; Machan, JT; Fadale, PD; Hulstyn, MJ – volume: 105 start-page: 185 year: 2013 end-page: 199 ident: j_bmc-2019-0014_ref_003 article-title: Epidemiology and Burden of Osteoarthritis publication-title: British Medical Bulletin contributor: fullname: Litwic, A; Edwards, MH; Dennison, EM; Cooper, C – volume: 16 start-page: 5659 year: 2017 end-page: 5666 ident: j_bmc-2019-0014_ref_030 article-title: Identification of key mRNAs and microRNAs in the pathogenesis and progression of osteoarthritis using microarray analysis publication-title: Molecular Medicine Reports contributor: fullname: Li, H; Bai, B; Wang, J; Xu, Z; Yan, S; Liu, G – volume: 15 start-page: 10 issue: 309 year: 2014 ident: j_bmc-2019-0014_ref_023 article-title: Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammation publication-title: BMC Musculoskeletal Disorders contributor: fullname: He, Y; Siebuhr, AS; Brandt-Hansen, NU; Wang, J; Su, D; Zheng, Q – volume: 5 start-page: 463 issue: 6 year: 2010 end-page: 466 ident: j_bmc-2019-0014_ref_010 article-title: What are Biomarkers publication-title: Current Opinion HIV AIDS contributor: fullname: Strimbu, K; Tavel, J – volume: 108 start-page: 5 issue: 27 year: 2011 ident: j_bmc-2019-0014_ref_035 article-title: Gilchrist DS,MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis publication-title: Proceedings of the National Academy of Sciences of the United States of America contributor: fullname: Kurowska-Stolarska, M; Alivernini, S; Ballantine, LE; Asquith, DL; Millar, NL – volume: 25 start-page: 409 issue: 3 year: 2006 end-page: 16 ident: j_bmc-2019-0014_ref_057 article-title: TNF-α in Promotion and Progression of Cancer publication-title: Cancer and Metastasis Reviews contributor: fullname: Balkwill, F. – volume: 30 start-page: 1246 issue: 9 year: 2015 end-page: 52 ident: j_bmc-2019-0014_ref_021 article-title: Age-related NADPH Oxidase (arNOX) Activity Correlated with Cartilage Degradation and Bony Changes in Age-related Osteoarthritis publication-title: Journal of Korean Medical Science contributor: fullname: Kim, MJ; Kim, HJ; Hong, YH; Lee, CK; Kim, YW; Shon, OJ – volume: 24 start-page: 4433 year: 2018 end-page: 4439 ident: j_bmc-2019-0014_ref_056 article-title: Effects of Tumor Necrosis Factor α (TNF-α) and Interleukina 10 (IL-10) on Intercellular Cell Adhesion Molecule-1 (ICAM-1) and Cluster of Differentiation 31 (CD31) in Human Coronary Artery Endothelial Cells publication-title: Medical Science Monitor contributor: fullname: Xue, M; Qiqige, C; Zhang, Q; Zhao, H; Su, L; Sun, P – volume: 11 start-page: 124 issue: 4 year: 2007 end-page: 8 ident: j_bmc-2019-0014_ref_064 article-title: The Kinin System - Bradykinin: Biological Effects and Clinical Implications publication-title: Multiple Role of the Kinin system - Bradykinin. Hippokratia contributor: fullname: Golias, Ch; Charalabopoulos, A; Stagikas, D; Charalabopoulos, K; Batistatou, A – volume: 20 start-page: e511 issue: 3 year: 2019 ident: j_bmc-2019-0014_ref_052 article-title: Moderate Physical Activity as a Prevention Method for Knee Osteoarthritis and the Role of Synoviocytes as Biological Key publication-title: International Journal of Molecular Science contributor: fullname: Castrogiovanni, P; Di, Rosa M; Ravalli, S; Castorina, A; Guglielmino, C; Imbesi, R – volume: 6 start-page: e21230 issue: 7 year: 2010 ident: j_bmc-2019-0014_ref_011 article-title: Differences between Human Plasma and Serum Metabolite Profiles publication-title: PLoS One contributor: fullname: Yu, Z; Kastenmüller, G; He, Y; Belcredi, P; Möller, G; Prehn, C – volume: 3 start-page: 441 year: 2003 end-page: 7 ident: j_bmc-2019-0014_ref_017 article-title: Cloning, expression and characterization of the murine Efemp1, a gene mutated in Doyne-Honeycomb retinal dystrophy publication-title: Gene Expression Patterns contributor: fullname: Ehlermann, J; Weber, S; Pfisterer, P; Schorle, H – volume: 92 start-page: 7257 issue: 16 year: 1995 end-page: 61 ident: j_bmc-2019-0014_ref_072 article-title: Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo publication-title: Proceedings of the National Academy of Sciences of the United States of America contributor: fullname: Yang, Y; Xiang, Z; Ertl, HC; Wilson, JM – volume: 16 start-page: 494 issue: 4 year: 1957 end-page: 502 ident: j_bmc-2019-0014_ref_008 article-title: Radiological Assessment of Osteo-Arthrosis publication-title: Annals of the Rheumatic Diseases contributor: fullname: Kellgren, JH; Lawrence, JS – volume: 9 start-page: 2852 issue: 6 year: 2017 end-page: 2864 ident: j_bmc-2019-0014_ref_032 article-title: Combination of circulating miR-19b-3p, miR-122-5p and miR-486-5p expressions correlates with risk and disease severity of knee osteoarthritis publication-title: American Journal of Translational Research contributor: fullname: Kong, R; Gao, J; Si, Y; Zhao, D – volume: 7 start-page: 14 year: 2017 ident: j_bmc-2019-0014_ref_004 article-title: Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis publication-title: Nature Scientific Reports contributor: fullname: Kolhe, R; Hunter, M; Liu, S; Jadeja, R; Pundkar, C; Mondal, A – volume: 43 start-page: 1864 issue: 10 year: 2016 end-page: 1870 ident: j_bmc-2019-0014_ref_042 article-title: Ability of a Urine Assay of Type II Collagen Cleavage by Collagenases to Detect Early Onset and Progression of Articular Cartilage Degeneration: Results from a Population-based Cohort Study publication-title: The Journal of Rheumatology contributor: fullname: Poole, AR; Ha, N; Bourdon, S; Sayre, EC; Guermazi, A; Cibere, J – volume: 52 start-page: 1 issue: 1 year: 2003 end-page: 7 ident: j_bmc-2019-0014_ref_050 article-title: Differentiation and Function of Osteoclasts publication-title: The Keio Journal of Medicine contributor: fullname: Miyamoto, T; Suda, T – volume: 10 start-page: 799 issue: 10 year: 2002 end-page: 807 ident: j_bmc-2019-0014_ref_028 article-title: Contribution of interleukin 17 to human cartilage degradation and synovial inflammation in osteoarthritis publication-title: Osteoarthritis and Cartilage contributor: fullname: Honorati, MC; Bovara, M; Cattini, L; Piacentini, A; Facchini, A – volume: 7 start-page: 277 issue: 2 year: 2003 end-page: 85 ident: j_bmc-2019-0014_ref_065 article-title: Bradykinin receptors as a therapeutic target publication-title: Expert Opinion on Therapeutic Targets contributor: fullname: Howl, J; Payne, SJ – volume: 36 start-page: 136 issue: 2 year: 2007 end-page: 9 ident: j_bmc-2019-0014_ref_051 article-title: Elevated IL-6 levels in the synovial fluid of osteoarthritis patients stem from plasma cells publication-title: Scandinavian Journal of Rheumatology contributor: fullname: Doss, F; Menard, J; Hauschild, M; Kreutzer, HJ; Mittlmeier, T; Müller-Steinhardt, M – volume: 8 start-page: 11 issue: 1 year: 2005 end-page: 17 ident: j_bmc-2019-0014_ref_022 article-title: The Role of Type X Collagen in Facilitating and Regulating Endochondral Ossification of Articular Cartilage publication-title: Orthodontics and Craniofacial Research contributor: fullname: Shen, G. – volume: 24 start-page: 672 issue: 4 year: 2016 end-page: 8 ident: j_bmc-2019-0014_ref_018 article-title: Fibulin-3 fragments are prognostic biomarkers of osteoarthritis incidence in overweight and obese women publication-title: Osteoarthritis and Cartilage contributor: fullname: Runhaar, J; Sanchez, C; Taralla, S; Henrotin, Y; Bierma-Zeinstra, SM – volume: 8 start-page: 2747 issue: 6 year: 2014 end-page: 2751 ident: j_bmc-2019-0014_ref_058 article-title: Expression levels of tumor necrosis factor-α and the corresponding receptors are correlated with trauma severity publication-title: Oncology Letters contributor: fullname: Liu, C; Tang, J – volume: 21 start-page: 6 year: 2013 ident: ref651 article-title: Synovial fluid levels of bradykinin correlate with biochemical markers for cartilage degradation and inflammation in knee osteoarthritis publication-title: Osteoarthritis and Cartilage – volume: 59 start-page: 149 year: 2016 ident: ref1331 article-title: Altered joint tribology in osteoarthritis: Reduced lubricin synthesis due to the inflammatory process publication-title: New horizons for therapeutic approaches. Anals of Physical and Rehabilitaiton Medicine – volume: 36 start-page: 136 year: 2007 ident: ref501 article-title: Elevated IL-6 levels in the synovial fluid of osteoarthritis patients stem from plasma cells publication-title: Scandinavian Journal of Rheumatology doi: 10.1080/03009740701250785 – volume: 127 start-page: 15 year: 2017 ident: ref301 article-title: Anastasopoulou and A. Tsezou. Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes publication-title: Clinical Epigenetics – volume: 10 start-page: 799 year: 2002 ident: ref271 article-title: Contribution of interleukin 17 to human cartilage degradation and synovial inflammation in osteoarthritis publication-title: Osteoarthritis and Cartilage doi: 10.1053/joca.2002.0829 – volume: 11 start-page: 124 year: 2007 ident: ref1361 article-title: The Kinin System - Bradykinin: Biological Effects and Clinical Implications publication-title: Multiple Role of the Kinin system - Bradykinin. Hippokratia – volume: 36 start-page: 136 year: 2007 ident: ref1231 article-title: Elevated IL-6 levels in the synovial fluid of osteoarthritis patients stem from plasma cells publication-title: Scandinavian Journal of Rheumatology doi: 10.1080/03009740701250785 – volume: 12 start-page: 6199 year: 2015 ident: ref1421 article-title: An insertion/deletion polymorphism at the microRNA-122 binding site in the interleukin-1α 3’-untranslated region is associated with a risk for osteoarthritis publication-title: Molecular Medicine Reports doi: 10.3892/mmr.2015.4121 – volume: 11 start-page: 537 year: 2010 ident: ref981 article-title: MicroRNA: Biogenesis, Function and Role in Cancer publication-title: Current Genomics doi: 10.2174/138920210793175895 – volume: 15 start-page: 10 year: 2014 ident: ref951 article-title: Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammation publication-title: BMC Musculoskeletal Disorders – volume: 16 start-page: 3419 year: 2018 ident: ref991 article-title: Plasma miR-136 can be used to screen patients with knee osteoarthritis from healthy controls by targeting IL-17 publication-title: Experimental and Therapeutic Medicine – volume: 29 start-page: 707 year: 2014 ident: ref51 article-title: Advantages of exercise in rehabilitation, treatment and prevention of altered morphological features in knee osteoarthritis publication-title: A narrative review. Histology And Histopathology – volume: 21 start-page: 1906 year: 2015 ident: ref1311 article-title: Interleukin-6 and Tumor Necrosis Factor Alpha in Synovial Fluid Are Associated with Progression of Radiographic Knee Osteoarthritis in Subjects with Previous Meniscectomy publication-title: Osteoarthritis and Cartilage – volume: 96 start-page: e7593 year: 2017 ident: ref1121 article-title: Comparative study of CTX-II, Zn2+, and Ca2+ from the urine for knee osteoarthritis patients and healthy individuals publication-title: Medicine doi: 10.1097/MD.0000000000007593 – volume: 289 start-page: 1504 year: 2000 ident: ref1211 article-title: Bone Resorption by Osteoclasts publication-title: Science doi: 10.1126/science.289.5484.1504 – volume: 56 start-page: i55 year: 2017 ident: ref851 article-title: Pathways leading to an immunological disease: systemic lupus erythematosus publication-title: Rheumatology doi: 10.1093/rheumatology/kew427 – volume: 59 start-page: 149 year: 2016 ident: ref601 article-title: Altered joint tribology in osteoarthritis: Reduced lubricin synthesis due to the inflammatory process publication-title: New horizons for therapeutic approaches. Anals of Physical and Rehabilitaiton Medicine – volume: 306 start-page: 645 year: 2014 ident: ref921 article-title: Age-related NADH oxidase (arNOX)-catalyzed oxidative damage to skin proteins publication-title: Archives of Dermatological Research doi: 10.1007/s00403-014-1472-8 – volume: 58 start-page: 1707 year: 2009 ident: ref591 article-title: Decreased Lubricin Concentrations and Markers of Joint Inflammation in Synovial Fluids from Patients with Anterior Cruciate Ligament Injury publication-title: Arthritis and Rheumatism – volume: 109 start-page: 14170 year: 2012 ident: ref1101 article-title: The role of intracellular calcium phosphate in osteoblast-mediated bone apatite formation publication-title: PNAS doi: 10.1073/pnas.1208916109 – volume: 116 start-page: 965 year: 2014 ident: ref611 article-title: Lubricin expression in human osteoarthritic knee meniscus and synovial fluid: A morphological, immunohistochemical and biochemical study publication-title: Acta Histochemica doi: 10.1016/j.acthis.2014.03.011 – volume: 58 start-page: 2420 year: 2008 ident: ref401 article-title: Characterization of Metalloprotease Cleavage Products of Human Articular Cartilage publication-title: Arthritis and Rheumatism doi: 10.1002/art.23654 – volume: 91 start-page: 99 year: 2010 ident: ref1251 article-title: Lack of Oxygen in Articular Cartilage: Consequences For Chondrocyte Biology publication-title: International Journal of Experimental Pathology doi: 10.1111/j.1365-2613.2010.00707.x – volume: 12 start-page: 6199 year: 2015 ident: ref691 article-title: An insertion/deletion polymorphism at the microRNA-122 binding site in the interleukin-1α 3’-untranslated region is associated with a risk for osteoarthritis publication-title: Molecular Medicine Reports doi: 10.3892/mmr.2015.4121 – volume: 127 start-page: 701 year: 2011 ident: ref111 article-title: Interleukins, from 1 to 37, and interferon-g: Receptors, functions, and roles in diseases publication-title: The Journal of Allergy and Clinical Immunology doi: 10.1016/j.jaci.2010.11.050 – volume: 45 start-page: 35 year: 2003 ident: ref721 article-title: Serologic markers of early rheumatoid arthritis publication-title: Folia Medica – volume: 30 start-page: 1246 year: 2015 ident: ref201 article-title: Age-related NADPH Oxidase (arNOX) Activity Correlated with Cartilage Degradation and Bony Changes in Age-related Osteoarthritis publication-title: Journal of Korean Medical Science doi: 10.3346/jkms.2015.30.9.1246 – volume: 14 start-page: 717 year: 2006 ident: ref871 article-title: Elevated Serum levels of Soluble Interleukin-4 receptor publication-title: Osteoarthritis and Cartilage doi: 10.1016/j.joca.2006.02.015 – volume: 116 start-page: 965 year: 2014 ident: ref1341 article-title: Lubricin expression in human osteoarthritic knee meniscus and synovial fluid: A morphological, immunohistochemical and biochemical study publication-title: Acta Histochemica doi: 10.1016/j.acthis.2014.03.011 – volume: 25 start-page: 409 year: 2006 ident: ref1291 article-title: TNF-α in Promotion and Progression of Cancer publication-title: Cancer and Metastasis Reviews doi: 10.1007/s10555-006-9005-3 – volume: 22 start-page: 5424 year: 2018 ident: ref281 article-title: Investigation for the role of CTX-III and microRNA-98 in diagnosis and treatment of osteoarthritis publication-title: European Review for Medical and Pharmacological Sciences – volume: 7 start-page: 277 year: 2003 ident: ref1371 article-title: Bradykinin receptors as a therapeutic target publication-title: Expert Opinion on Therapeutic Targets doi: 10.1517/14728222.7.2.277 – volume: 24 start-page: 4433 year: 2018 ident: ref551 article-title: Effects of Tumor Necrosis Factor α (TNF-α) and Interleukina 10 (IL-10) on Intercellular Cell Adhesion Molecule-1 (ICAM-1) and Cluster of Differentiation 31 (CD31) in Human Coronary Artery Endothelial Cells publication-title: Medical Science Monitor doi: 10.12659/MSM.906838 – volume: 51 start-page: 1010 year: 2010 ident: ref1191 article-title: Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids publication-title: Journal of Lipid Research doi: 10.1194/jlr.M001099 – volume: 4 start-page: 33 year: 2009 ident: ref231 article-title: Cartilage Oligomeric Matrix Protein: A biomarker of Arthritis publication-title: Biomarker Insights – volume: 7 start-page: 3584 year: 2017 ident: ref1431 article-title: MicroRNA-29a Counteracts Synovitis in Knee Osteoarthritis Pathogenesis by Targeting VEGF publication-title: Scientific Reports doi: 10.1038/s41598-017-03616-w – volume: 6 start-page: e21230 year: 2010 ident: ref831 article-title: Differences between Human Plasma and Serum Metabolite Profiles publication-title: PLoS One – volume: 43 start-page: 1864 year: 2016 ident: ref1141 article-title: Ability of a Urine Assay of Type II Collagen Cleavage by Collagenases to Detect Early Onset and Progression of Articular Cartilage Degeneration: Results from a Population-based Cohort Study publication-title: The Journal of Rheumatology doi: 10.3899/jrheum.150917 – volume: 12 start-page: 1774 year: 2009 ident: ref661 article-title: Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis publication-title: Arthritis Research and Therapy – volume: 14 start-page: 10529 year: 2014 ident: ref541 article-title: Association Between Hypoxia-Inducible Factor-1a Levels in Serum and Synovial Fluid with the Radiographic Severity of Knee Osteoarthritis publication-title: Genetic Molecular Research – volume: 91 start-page: 99 year: 2010 ident: ref521 article-title: Lack of Oxygen in Articular Cartilage: Consequences For Chondrocyte Biology publication-title: International Journal of Experimental Pathology doi: 10.1111/j.1365-2613.2010.00707.x – volume: 8 start-page: 2747 year: 2014 ident: ref1301 article-title: Expression levels of tumor necrosis factor-α and the corresponding receptors are correlated with trauma severity publication-title: Oncology Letters doi: 10.3892/ol.2014.2575 – volume: 33 start-page: e22648 year: 2019 ident: ref331 article-title: Change of miRNA expression profiles in patients with knee osteoarthritis before and after celecoxib treatment publication-title: Journal of Clinical Laboratory Analysis doi: 10.1002/jcla.22648 – volume: 7 start-page: 14 year: 2017 ident: ref761 article-title: Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis publication-title: Nature Scientific Reports – volume: 8 start-page: 11 year: 2005 ident: ref941 article-title: The Role of Type X Collagen in Facilitating and Regulating Endochondral Ossification of Articular Cartilage publication-title: Orthodontics and Craniofacial Research doi: 10.1111/j.1601-6343.2004.00308.x – volume: 3 start-page: 441 year: 2003 ident: ref891 article-title: Cloning, expression and characterization of the murine Efemp1, a gene mutated in Doyne-Honeycomb retinal dystrophy publication-title: Gene Expression Patterns doi: 10.1016/S1567-133X(03)00084-X – volume: 13 start-page: 609 year: 2016 ident: ref351 article-title: Current State of the Art for Enhancing Urine Biomarker Discovery Volume 13 publication-title: Expert Review Proteomics doi: 10.1080/14789450.2016.1190651 – volume: 11 start-page: 537 year: 2010 ident: ref251 article-title: MicroRNA: Biogenesis, Function and Role in Cancer publication-title: Current Genomics doi: 10.2174/138920210793175895 – volume: 12 start-page: 1774 year: 2009 ident: ref1391 article-title: Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis publication-title: Arthritis Research and Therapy – volume: 16 start-page: 494 year: 1957 ident: ref71 article-title: Radiological Assessment of Osteo-Arthrosis publication-title: Annals of the Rheumatic Diseases doi: 10.1136/ard.16.4.494 – volume: 6 start-page: e21230 year: 2010 ident: ref101 article-title: Differences between Human Plasma and Serum Metabolite Profiles publication-title: PLoS One – volume: 5 start-page: 463 year: 2010 ident: ref821 article-title: What are Biomarkers publication-title: Current Opinion HIV AIDS doi: 10.1097/COH.0b013e32833ed177 – volume: 58 start-page: 565 year: 2019 ident: ref1351 article-title: Physical activity and Mediterranean diet based on olive tree phenolic compounds from two different geographical areas have protective effects on early osteoarthritis, muscle atrophy and hepatic steatosis publication-title: European Journal of Nutrition doi: 10.1007/s00394-018-1632-2 – volume: 51 start-page: 1010 year: 2010 ident: ref461 article-title: Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids publication-title: Journal of Lipid Research doi: 10.1194/jlr.M001099 – volume: 8 start-page: 2747 year: 2014 ident: ref571 article-title: Expression levels of tumor necrosis factor-α and the corresponding receptors are correlated with trauma severity publication-title: Oncology Letters doi: 10.3892/ol.2014.2575 – volume: 58 start-page: 565 year: 2019 ident: ref621 article-title: Physical activity and Mediterranean diet based on olive tree phenolic compounds from two different geographical areas have protective effects on early osteoarthritis, muscle atrophy and hepatic steatosis publication-title: European Journal of Nutrition doi: 10.1007/s00394-018-1632-2 – volume: 11 start-page: 124 year: 2007 ident: ref631 article-title: The Kinin System - Bradykinin: Biological Effects and Clinical Implications publication-title: Multiple Role of the Kinin system - Bradykinin. Hippokratia – volume: 24 start-page: 672 year: 2016 ident: ref901 article-title: Fibulin-3 fragments are prognostic biomarkers of osteoarthritis incidence in overweight and obese women publication-title: Osteoarthritis and Cartilage doi: 10.1016/j.joca.2015.10.013 – volume: 25 start-page: e222 year: 2015 ident: ref41 article-title: Physical activity ameliorates cartilage degeneration in a rat model of aging: a study on lubricin expression publication-title: Scandinavian Journal of Medicine and Science In Sports doi: 10.1111/sms.12290 – volume: 30 start-page: 1246 year: 2015 ident: ref931 article-title: Age-related NADPH Oxidase (arNOX) Activity Correlated with Cartilage Degradation and Bony Changes in Age-related Osteoarthritis publication-title: Journal of Korean Medical Science doi: 10.3346/jkms.2015.30.9.1246 – volume: 36 start-page: 4875 year: 2017 ident: ref151 article-title: Tumor-derived fibulin-3 activates pro-invasive NF-kappa B signaling in glioblastoma cells and their microenvironment publication-title: Oncogene doi: 10.1038/onc.2017.109 – volume: 31 start-page: 999 year: 2013 ident: ref971 article-title: Serum cartilage oligomeric matrix protein (COMP) in knee osteoarthritis: A novel diagnostic and prognostic biomarker publication-title: Journal of Orthopaedic Research doi: 10.1002/jor.22324 – volume: 11 start-page: 119 year: 1998 ident: ref361 article-title: Role of Zinc in Bone Formation and Bone Resorption publication-title: The Journal of Trace Elements in Experimental Medicine doi: 10.1002/(SICI)1520-670X(1998)11:2/3<119::AID-JTRA5>3.0.CO;2-3 – volume: 15 start-page: 1095 year: 2006 ident: ref861 article-title: Increased frequency of peripheral blood follicular helper T cells and elevated serum IL‑21 levels in patients with knee osteoarthritis publication-title: Molecular Medicine Reports – volume: 16 start-page: 494 year: 1957 ident: ref801 article-title: Radiological Assessment of Osteo-Arthrosis publication-title: Annals of the Rheumatic Diseases doi: 10.1136/ard.16.4.494 – volume: 25 start-page: 409 year: 2006 ident: ref561 article-title: TNF-α in Promotion and Progression of Cancer publication-title: Cancer and Metastasis Reviews doi: 10.1007/s10555-006-9005-3 – volume: 11 start-page: 119 year: 1998 ident: ref1091 article-title: Role of Zinc in Bone Formation and Bone Resorption publication-title: The Journal of Trace Elements in Experimental Medicine doi: 10.1002/(SICI)1520-670X(1998)11:2/3<119::AID-JTRA5>3.0.CO;2-3 – volume: 127 start-page: 701 year: 2011 ident: ref841 article-title: Interleukins, from 1 to 37, and interferon-g: Receptors, functions, and roles in diseases publication-title: The Journal of Allergy and Clinical Immunology doi: 10.1016/j.jaci.2010.11.050 – volume: 22 start-page: 363 year: 2014 ident: ref791 article-title: OARSI guidelines for the nonsurgical management of knee osteoarthritis publication-title: Osteoarthritis Cartilage doi: 10.1016/j.joca.2014.01.003 – volume: 122 start-page: 487 year: 2012 ident: ref1171 article-title: IL-17/IL-17 receptor system in autoimmune disease: mechanisms and therapeutic potential publication-title: Clinical Science doi: 10.1042/CS20110496 – volume: 96 start-page: e7593 year: 2017 ident: ref391 article-title: Comparative study of CTX-II, Zn2+, and Ca2+ from the urine for knee osteoarthritis patients and healthy individuals publication-title: Medicine doi: 10.1097/MD.0000000000007593 – volume: 22 start-page: 363 year: 2014 ident: ref61 article-title: OARSI guidelines for the nonsurgical management of knee osteoarthritis publication-title: Osteoarthritis Cartilage doi: 10.1016/j.joca.2014.01.003 – volume: 15 start-page: 1095 year: 2006 ident: ref131 article-title: Increased frequency of peripheral blood follicular helper T cells and elevated serum IL‑21 levels in patients with knee osteoarthritis publication-title: Molecular Medicine Reports – volume: 36 start-page: 4875 year: 2017 ident: ref881 article-title: Tumor-derived fibulin-3 activates pro-invasive NF-kappa B signaling in glioblastoma cells and their microenvironment publication-title: Oncogene doi: 10.1038/onc.2017.109 – volume: 20 start-page: e511 year: 2019 ident: ref1241 article-title: Moderate Physical Activity as a Prevention Method for Knee Osteoarthritis and the Role of Synoviocytes as Biological Key publication-title: International Journal of Molecular Science doi: 10.3390/ijms20030511 – volume: 14 start-page: 717 year: 2006 ident: ref141 article-title: Elevated Serum levels of Soluble Interleukin-4 receptor publication-title: Osteoarthritis and Cartilage doi: 10.1016/j.joca.2006.02.015 – volume: 58 start-page: 2420 year: 2008 ident: ref1131 article-title: Characterization of Metalloprotease Cleavage Products of Human Articular Cartilage publication-title: Arthritis and Rheumatism doi: 10.1002/art.23654 – volume: 127 start-page: 15 year: 2017 ident: ref1031 article-title: Anastasopoulou and A. Tsezou. Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes publication-title: Clinical Epigenetics – volume: 45 start-page: 35 year: 2003 ident: ref1451 article-title: Serologic markers of early rheumatoid arthritis publication-title: Folia Medica – volume: 24 start-page: 5292 year: 2018 ident: ref681 article-title: miR-145-5p Increases Osteoclast Numbers In Vitro and Aggravates Bone Erosion in Collagen-Induced Arthritis by Targeting Osteoprotegerin publication-title: Medical Science Monitor doi: 10.12659/MSM.908219 – volume: 7 start-page: 14 year: 2017 ident: ref31 article-title: Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis publication-title: Nature Scientific Reports – volume: 15 start-page: 10 year: 2014 ident: ref221 article-title: Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammation publication-title: BMC Musculoskeletal Disorders – volume: 16 start-page: 3419 year: 2018 ident: ref261 article-title: Plasma miR-136 can be used to screen patients with knee osteoarthritis from healthy controls by targeting IL-17 publication-title: Experimental and Therapeutic Medicine – volume: 105 start-page: 185 year: 2013 ident: ref751 article-title: Epidemiology and Burden of Osteoarthritis publication-title: British Medical Bulletin doi: 10.1093/bmb/lds038 – volume: 108 start-page: 5 year: 2011 ident: ref1071 article-title: Gilchrist DS,MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis publication-title: Proceedings of the National Academy of Sciences of the United States of America – volume: 29 start-page: 707 year: 2014 ident: ref781 article-title: Advantages of exercise in rehabilitation, treatment and prevention of altered morphological features in knee osteoarthritis publication-title: A narrative review. Histology And Histopathology – volume: 92 start-page: 7257 year: 1995 ident: ref1441 article-title: Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo publication-title: Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.92.16.7257 – volume: 5 start-page: 463 year: 2010 ident: ref91 article-title: What are Biomarkers publication-title: Current Opinion HIV AIDS doi: 10.1097/COH.0b013e32833ed177 – volume: 3 start-page: 441 year: 2003 ident: ref161 article-title: Cloning, expression and characterization of the murine Efemp1, a gene mutated in Doyne-Honeycomb retinal dystrophy publication-title: Gene Expression Patterns doi: 10.1016/S1567-133X(03)00084-X – volume: 8 start-page: 11 year: 2005 ident: ref211 article-title: The Role of Type X Collagen in Facilitating and Regulating Endochondral Ossification of Articular Cartilage publication-title: Orthodontics and Craniofacial Research doi: 10.1111/j.1601-6343.2004.00308.x – volume: 52 start-page: 1 year: 2003 ident: ref491 article-title: Differentiation and Function of Osteoclasts publication-title: The Keio Journal of Medicine doi: 10.2302/kjm.52.1 – volume: 21 start-page: 6 year: 2013 ident: ref1381 article-title: Synovial fluid levels of bradykinin correlate with biochemical markers for cartilage degradation and inflammation in knee osteoarthritis publication-title: Osteoarthritis and Cartilage – volume: 13 start-page: 609 year: 2016 ident: ref1081 article-title: Current State of the Art for Enhancing Urine Biomarker Discovery Volume 13 publication-title: Expert Review Proteomics doi: 10.1080/14789450.2016.1190651 – volume: 16 start-page: 5659 year: 2017 ident: ref291 article-title: Identification of key mRNAs and microRNAs in the pathogenesis and progression of osteoarthritis using microarray analysis publication-title: Molecular Medicine Reports doi: 10.3892/mmr.2017.7251 – volume: 283 start-page: 11535 year: 2008 ident: ref471 article-title: Interleukin-6 Directly Inhibits Osteoclast Differentiation by Suppressing Receptor Activator of NF-κB Signaling Pathways publication-title: Journal of Biological Chemistry doi: 10.1074/jbc.M607999200 – volume: 25 start-page: e222 year: 2015 ident: ref771 article-title: Physical activity ameliorates cartilage degeneration in a rat model of aging: a study on lubricin expression publication-title: Scandinavian Journal of Medicine and Science In Sports doi: 10.1111/sms.12290 – volume: 26 start-page: 1059 year: 2010 ident: ref1111 article-title: The requirement of zinc and calcium ions for functional MMP activity in demineralized dentin matrices publication-title: Dental Materials doi: 10.1016/j.dental.2010.07.006 – volume: 58 start-page: 1707 year: 2009 ident: ref1321 article-title: Decreased Lubricin Concentrations and Markers of Joint Inflammation in Synovial Fluids from Patients with Anterior Cruciate Ligament Injury publication-title: Arthritis and Rheumatism – volume: 56 start-page: i55 year: 2017 ident: ref121 article-title: Pathways leading to an immunological disease: systemic lupus erythematosus publication-title: Rheumatology doi: 10.1093/rheumatology/kew427 – volume: 16 start-page: 5659 year: 2017 ident: ref1021 article-title: Identification of key mRNAs and microRNAs in the pathogenesis and progression of osteoarthritis using microarray analysis publication-title: Molecular Medicine Reports doi: 10.3892/mmr.2017.7251 – volume: 283 start-page: 11535 year: 2008 ident: ref1201 article-title: Interleukin-6 Directly Inhibits Osteoclast Differentiation by Suppressing Receptor Activator of NF-κB Signaling Pathways publication-title: Journal of Biological Chemistry doi: 10.1074/jbc.M607999200 – volume: 12 start-page: R229 year: 2010 ident: ref1151 article-title: Changes in Serum and Synovial Fluid Biomarkers after Acute Injury publication-title: Arthritis Research and Therapy doi: 10.1186/ar3216 – volume: 24 start-page: 1577 year: 2016 ident: ref1401 article-title: Identification of synovial fluid microRNA signature in knee osteoarthritis: differentiating early- and late-stage knee osteoarthritis publication-title: Osteoarthritis and Cartilage doi: 10.1016/j.joca.2016.04.019 – volume: 7 start-page: 3584 year: 2017 ident: ref701 article-title: MicroRNA-29a Counteracts Synovitis in Knee Osteoarthritis Pathogenesis by Targeting VEGF publication-title: Scientific Reports doi: 10.1038/s41598-017-03616-w – volume: 26 start-page: 1059 year: 2010 ident: ref381 article-title: The requirement of zinc and calcium ions for functional MMP activity in demineralized dentin matrices publication-title: Dental Materials doi: 10.1016/j.dental.2010.07.006 – volume: 24 start-page: 672 year: 2016 ident: ref171 article-title: Fibulin-3 fragments are prognostic biomarkers of osteoarthritis incidence in overweight and obese women publication-title: Osteoarthritis and Cartilage doi: 10.1016/j.joca.2015.10.013 – volume: 20 start-page: e511 year: 2019 ident: ref511 article-title: Moderate Physical Activity as a Prevention Method for Knee Osteoarthritis and the Role of Synoviocytes as Biological Key publication-title: International Journal of Molecular Science doi: 10.3390/ijms20030511 – volume: 17 start-page: 12 year: 2016 ident: ref81 article-title: Physical examination findings and their relationship with performance-based function in adults with knee osteoarthritis publication-title: BioMed Central Musculoskeletal Disorders – volume: 10 start-page: 799 year: 2002 ident: ref1001 article-title: Contribution of interleukin 17 to human cartilage degradation and synovial inflammation in osteoarthritis publication-title: Osteoarthritis and Cartilage doi: 10.1053/joca.2002.0829 – volume: 24 start-page: 1577 year: 2016 ident: ref671 article-title: Identification of synovial fluid microRNA signature in knee osteoarthritis: differentiating early- and late-stage knee osteoarthritis publication-title: Osteoarthritis and Cartilage doi: 10.1016/j.joca.2016.04.019 – volume: 15 start-page: 6 year: 2018 ident: ref11 article-title: Platelet-rich plasma shows beneficial effects for patients with knee osteoarthritis by suppressing inflammatory factors publication-title: Journal of Experimental and Therapeutic Medicine – volume: 4 start-page: 33 year: 2009 ident: ref961 article-title: Cartilage Oligomeric Matrix Protein: A biomarker of Arthritis publication-title: Biomarker Insights – volume: 306 start-page: 645 year: 2014 ident: ref191 article-title: Age-related NADH oxidase (arNOX)-catalyzed oxidative damage to skin proteins publication-title: Archives of Dermatological Research doi: 10.1007/s00403-014-1472-8 – volume: 43 start-page: 1864 year: 2016 ident: ref411 article-title: Ability of a Urine Assay of Type II Collagen Cleavage by Collagenases to Detect Early Onset and Progression of Articular Cartilage Degeneration: Results from a Population-based Cohort Study publication-title: The Journal of Rheumatology doi: 10.3899/jrheum.150917 – volume: 24 start-page: 4433 year: 2018 ident: ref1281 article-title: Effects of Tumor Necrosis Factor α (TNF-α) and Interleukina 10 (IL-10) on Intercellular Cell Adhesion Molecule-1 (ICAM-1) and Cluster of Differentiation 31 (CD31) in Human Coronary Artery Endothelial Cells publication-title: Medical Science Monitor doi: 10.12659/MSM.906838 – volume: 95 start-page: e3585 year: 2016 ident: ref321 article-title: Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials publication-title: Medicine doi: 10.1097/MD.0000000000003585 – volume: 15 start-page: 6 year: 2018 ident: ref741 article-title: Platelet-rich plasma shows beneficial effects for patients with knee osteoarthritis by suppressing inflammatory factors publication-title: Journal of Experimental and Therapeutic Medicine – volume: 289 start-page: 1504 year: 2000 ident: ref481 article-title: Bone Resorption by Osteoclasts publication-title: Science doi: 10.1126/science.289.5484.1504 – volume: 9 start-page: 2852 year: 2017 ident: ref1041 article-title: Combination of circulating miR-19b-3p, miR-122-5p and miR-486-5p expressions correlates with risk and disease severity of knee osteoarthritis publication-title: American Journal of Translational Research – volume: 22 start-page: 5424 year: 2018 ident: ref1011 article-title: Investigation for the role of CTX-III and microRNA-98 in diagnosis and treatment of osteoarthritis publication-title: European Review for Medical and Pharmacological Sciences – volume: 92 start-page: 7257 year: 1995 ident: ref711 article-title: Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo publication-title: Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.92.16.7257 – volume: 17 start-page: 12 year: 2016 ident: ref811 article-title: Physical examination findings and their relationship with performance-based function in adults with knee osteoarthritis publication-title: BioMed Central Musculoskeletal Disorders – volume: 31 start-page: 999 year: 2013 ident: ref241 article-title: Serum cartilage oligomeric matrix protein (COMP) in knee osteoarthritis: A novel diagnostic and prognostic biomarker publication-title: Journal of Orthopaedic Research doi: 10.1002/jor.22324 – volume: 21 start-page: 1732 year: 2015 ident: ref451 article-title: Correlation of IL-17 Level in Synovia and Severity of Knee Osteoarthritis publication-title: International Medical Journal of Experimental and Clinical Research – volume: 21 start-page: 1906 year: 2015 ident: ref581 article-title: Interleukin-6 and Tumor Necrosis Factor Alpha in Synovial Fluid Are Associated with Progression of Radiographic Knee Osteoarthritis in Subjects with Previous Meniscectomy publication-title: Osteoarthritis and Cartilage – volume: 9 start-page: 2852 year: 2017 ident: ref311 article-title: Combination of circulating miR-19b-3p, miR-122-5p and miR-486-5p expressions correlates with risk and disease severity of knee osteoarthritis publication-title: American Journal of Translational Research – volume: 2 start-page: e60 year: 2013 ident: ref1161 article-title: IL-17 Cytokines in Immunity and Inflammation publication-title: Emerging Microbes and Infections – volume: 21 start-page: 1732 year: 2015 ident: ref1181 article-title: Correlation of IL-17 Level in Synovia and Severity of Knee Osteoarthritis publication-title: International Medical Journal of Experimental and Clinical Research – volume: 309 start-page: C775 year: 2015 ident: ref531 article-title: Regulation of Cell Proliferation by Hypoxia-Inducible Factors publication-title: American Physiological Society doi: 10.1152/ajpcell.00279.2015 – volume: 109 start-page: 14170 year: 2012 ident: ref371 article-title: The role of intracellular calcium phosphate in osteoblast-mediated bone apatite formation publication-title: PNAS doi: 10.1073/pnas.1208916109 – volume: 309 start-page: C775 year: 2015 ident: ref1261 article-title: Regulation of Cell Proliferation by Hypoxia-Inducible Factors publication-title: American Physiological Society doi: 10.1152/ajpcell.00279.2015 – volume: 108 start-page: 5 year: 2011 ident: ref341 article-title: Gilchrist DS,MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis publication-title: Proceedings of the National Academy of Sciences of the United States of America – volume: 95 start-page: e3585 year: 2016 ident: ref1051 article-title: Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials publication-title: Medicine doi: 10.1097/MD.0000000000003585 – volume: 33 start-page: e22648 year: 2019 ident: ref1061 article-title: Change of miRNA expression profiles in patients with knee osteoarthritis before and after celecoxib treatment publication-title: Journal of Clinical Laboratory Analysis doi: 10.1002/jcla.22648 – volume: 7 start-page: 277 year: 2003 ident: ref641 article-title: Bradykinin receptors as a therapeutic target publication-title: Expert Opinion on Therapeutic Targets doi: 10.1517/14728222.7.2.277 – volume: 52 start-page: 1 year: 2003 ident: ref1221 article-title: Differentiation and Function of Osteoclasts publication-title: The Keio Journal of Medicine doi: 10.2302/kjm.52.1 – volume: 122 start-page: 487 year: 2012 ident: ref441 article-title: IL-17/IL-17 receptor system in autoimmune disease: mechanisms and therapeutic potential publication-title: Clinical Science doi: 10.1042/CS20110496 – volume: 12 start-page: R229 year: 2010 ident: ref421 article-title: Changes in Serum and Synovial Fluid Biomarkers after Acute Injury publication-title: Arthritis Research and Therapy doi: 10.1186/ar3216 – volume: 55 start-page: 561 year: 2002 ident: ref911 article-title: NADPH oxidase(s): new source(s) of reactive oxygen species in the vascular system?’ publication-title: Journal of Clinical Pathology doi: 10.1136/jcp.55.8.561 – volume: 24 start-page: 5292 year: 2018 ident: ref1411 article-title: miR-145-5p Increases Osteoclast Numbers In Vitro and Aggravates Bone Erosion in Collagen-Induced Arthritis by Targeting Osteoprotegerin publication-title: Medical Science Monitor doi: 10.12659/MSM.908219 – volume: 105 start-page: 185 year: 2013 ident: ref21 article-title: Epidemiology and Burden of Osteoarthritis publication-title: British Medical Bulletin doi: 10.1093/bmb/lds038 – volume: 14 start-page: 10529 year: 2014 ident: ref1271 article-title: Association Between Hypoxia-Inducible Factor-1a Levels in Serum and Synovial Fluid with the Radiographic Severity of Knee Osteoarthritis publication-title: Genetic Molecular Research – volume: 55 start-page: 561 year: 2002 ident: ref181 article-title: NADPH oxidase(s): new source(s) of reactive oxygen species in the vascular system?’ publication-title: Journal of Clinical Pathology doi: 10.1136/jcp.55.8.561 – volume: 2 start-page: e60 year: 2013 ident: ref431 article-title: IL-17 Cytokines in Immunity and Inflammation publication-title: Emerging Microbes and Infections |
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Snippet | Osteoarthritis (OA) is a chronic degenerative joint disease. The pathogenesis is poorly understood. What is known is that OA is characterized by imbalance in... |
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SubjectTerms | Aging Arthritis Biomarker Biomarkers Chondrocytes Diagnosis Endocrinology Gene expression Joint diseases miRNA Oncology Osteoarthritis Pain Synovial fluid Urine |
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Title | Advances in Molecular biomarker for early diagnosis of Osteoarthritis |
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