Characterization of circulating lymphocytes by monoclonal antibodies in childhood and adult leprosy

Peripheral blood lymphocyte assays using monoclonal antibodies were done in 66 patients with leprosy, consisting of 25 children and 41 adults. The results were statistically analyzed for correlations, if any, among the different age groups and matched controls. The results, however, failed to show a...

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Bibliographic Details
Published inInternational journal of dermatology Vol. 30; no. 11; p. 780
Main Authors Sehgal, V N, Chaudhry, A, Sharma, V K, Gupta, C K
Format Journal Article
LanguageEnglish
Published England 01.11.1991
Subjects
Adolescent
Adult
Age Factors
Antibodies, Monoclonal
B-Lymphocytes
CD4-CD8 Ratio
Child
Child, Preschool
Female
Humans
Leprosy - blood
Leprosy - immunology
Leukocyte Count
Male
Middle Aged
T-Lymphocytes
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Summary:Peripheral blood lymphocyte assays using monoclonal antibodies were done in 66 patients with leprosy, consisting of 25 children and 41 adults. The results were statistically analyzed for correlations, if any, among the different age groups and matched controls. The results, however, failed to show any significant correlation, nor was it possible to draw any conclusion as to why the disease spectrum in children tends to be incomplete (ie, there is a low incidence of the highly bacilliferous form of disease expression).
ISSN:0011-9059
DOI:10.1111/j.1365-4362.1991.tb04786.x