Place of diagnostic tools in the identification of Anaerobiospirillum succiniciproducens bacteraemia

• Published in: Anaerobe Vol. 39; pp. 28 - 30
• Main Authors: Decroix, V., Pluquet, E., Choquet, M., Ammenouche, N., Castelain, S., Guiheneuf, R.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2016; Elsevier Masson
• Subjects: 16s rRNA sequencing; Anaerobiospirillum - classification; Anaerobiospirillum - genetics; Anaerobiospirillum - isolation & purification; Anaerobiospirillum succiniciproducens; Anti-Bacterial Agents - therapeutic use; Bacteraemia; beta-Lactams - therapeutic use; Ciprofloxacin - therapeutic use; Clindamycin - therapeutic use; Delayed Diagnosis; Drug Resistance, Bacterial; Gram-negative anaerobic; Gram-Negative Bacterial Infections - diagnosis; Gram-Negative Bacterial Infections - drug therapy; Gram-Negative Bacterial Infections - microbiology; Gram-Negative Bacterial Infections - pathology; Humans; Life Sciences; Male; Microbial Sensitivity Tests; Middle Aged; Pelvis - injuries; RNA, Ribosomal, 16S - genetics; Rod-shaped bacteria; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Bacteraemia; Rod-shaped bacteria; 16s rRNA sequencing; Gram-negative anaerobic; Anaerobiospirillum succiniciproducens
• ISSN: 1075-9964; 1095-8274
• DOI: 10.1016/j.anaerobe.2016.02.005

Anaerobiospirillum succiniciproducens is a rare but potentially lethal pathogen. We report a case of A. succiniciproducens bloodstream infection in a 55-year-old man hospitalized for pelvic trauma. The strain was identified by 16sRNA sequencing after several failures of identification by MALDI-TOF MS. The strain was susceptible to beta-lactam antibiotics and ciprofloxacin, but resistant to macrolides and clindamycin. Identification tools must be improved to enhance our knowledge on this rare pathogen and to define optimal therapy. •Anaerobiospirillum succiniciproducens is a significant human pathogen.•Identification in clinical samples is difficult.•16sRNA sequencing is the best identification tool at the present time.•MALDI-TOF databases should include this rare pathogen.