ABNORMAL ERPS AND HIGH FREQUENCY BANDS POWER IN MULTIPLE SCLEROSIS

Event-related potentials (ERPs) and power spectral density (PSD) were registered during an auditory-oddball paradigm in 11 MS patients. These patients showed a decrease in the amplitude of P2 and N2 components and a delayed P3 latency compared to control subjects suggesting that the attentional orie...

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Bibliographic Details
Published inInternational journal of neuroscience Vol. 118; no. 1; pp. 27 - 38
Main Authors VÁZQUEZ-MARRUFO, M., GONZÁLEZ-ROSA, J. J., VAQUERO, E., DUQUE, P., ESCERA, C., BORGES, M., IZQUIERDO, G., GÓMEZ, C. M.
Format Journal Article
LanguageEnglish
Published England Informa UK Ltd 2008
Taylor & Francis
Subjects
Acoustic Stimulation
Adult
Attention
auditory oddball
Discrimination (Psychology)
Electroencephalography
ERPs
Evoked Potentials, Auditory
Female
frequency bands
Humans
Male
Middle Aged
multiple sclerosis
Multiple Sclerosis, Relapsing-Remitting - physiopathology
Orientation
PSD
Reaction Time
Sound Localization
Sound Spectrography
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Summary:Event-related potentials (ERPs) and power spectral density (PSD) were registered during an auditory-oddball paradigm in 11 MS patients. These patients showed a decrease in the amplitude of P2 and N2 components and a delayed P3 latency compared to control subjects suggesting that the attentional orienting mechanism in the auditory modality is affected in MS. The PSD analysis showed that MS patients exhibited an increased power in beta and gamma bands. The combined analysis of frequency and time domain suggested diverse phenomena that occurred in the MS patient group related with the EEG background or the motivational status.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0020-7454
1563-5279
1543-5245
DOI:10.1080/00207450601041906